World's Best Scientists 2026 revealed!
Award Badge
Genetics
Korea
2024
Award Badge
Genetics and Molecular Biology
Korea
2024

D-Index & Metrics

Genetics

D-Index
103
Citations
99333
World Ranking
657
National Ranking
332

Medicine

D-Index
106
Citations
101810
World Ranking
6346
National Ranking
3387

Research.com Recognitions

  • 2024 - Research.com Genetics in Korea Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Korea Leader Award
  • 2023 - Research.com Genetics in Korea Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Korea Leader Award
  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Charles Lee is affiliated with The Jackson Laboratory in the United States. Their work primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with extensive contributions also in Medicine. Within these fields, their research focus includes Molecular Biology, Genetics, Oncology, Plant Science, and Surgery.

The scientist's main research topics cover a variety of genetic and genomic areas such as:

  • Chromosomal and Genetic Variations
  • Genomic variations and chromosomal abnormalities
  • Genomics and Phylogenetic Studies
  • Genomics and Rare Diseases
  • Cancer Genomics and Diagnostics
  • Cancer Research and Treatments
  • Cancer Cells and Metastasis

Charles Lee has contributed to multiple scientific publications, with frequent appearances in venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature
  • Nature Communications
  • Cancer Research
  • SSRN Electronic Journal

Frequent co-authors collaborating with Charles Lee include:

  • Evan E. Eichler
  • Qihui Zhu
  • Feyza Yilmaz
  • Jan O. Korbel
  • Tobias Marschall

Among recent publications, notable papers include:

  • High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios (2022, Cell)
  • Haplotype-resolved diverse human genomes and integrated analysis of structural variation (2021, Science)
  • Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice (2021, Nature Microbiology)
  • Fully phased human genome assembly without parental data using single-cell strand sequencing and long reads (2020, Nature Biotechnology)
  • Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts (2021, Nature Genetics)

Charles Lee has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS), an award received in 2012.

Best Publications

  • A global reference for human genetic variation.

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling

    Jeffrey A. Engelman;Kreshnik Zejnullahu;Tetsuya Mitsudomi;Youngchul Song

  • Global variation in copy number in the human genome

    Richard Redon;Shumpei Ishikawa;Karen R. Fitch;Lars Feuk

  • The zebrafish reference genome sequence and its relationship to the human genome.

    Kerstin Howe;Matthew D. Clark;Carlos F. Torroja;Carlos F. Torroja;James Torrance

  • Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer

    S.A. Tomlins;D.R. Rhodes;S. Perner;S.M. Dhanasekaran

  • Integrating common and rare genetic variation in diverse human populations

    D M Altshuler;R A Gibbs;L Peltonen

  • Detection of large-scale variation in the human genome.

    A John Iafrate;Lars Feuk;Miguel N Rivera;Miguel N Rivera;Marc L Listewnik

  • Consensus Statement : Chromosomal Microarray Is a First-Tier Clinical Diagnostic Test for Individuals with Developmental Disabilities or Congenital Anomalies

    David T. Miller;Margaret P. Adam;Margaret P. Adam;Swaroop Aradhya;Leslie G. Biesecker

  • An integrated map of structural variation in 2,504 human genomes

    Peter H. Sudmant;Tobias Rausch;Eugene J. Gardner;Robert E. Handsaker;Robert E. Handsaker

  • Origins and functional impact of copy number variation in the human genome

    Donald F. Conrad;Dalila Pinto;Richard Redon;Richard Redon;Lars Feuk;Lars Feuk

  • Relative Impact of Nucleotide and Copy Number Variation on Gene Expression Phenotypes

    Barbara E. Stranger;Matthew S. Forrest;Mark Dunning;Catherine E. Ingle

  • Diet and the evolution of human amylase gene copy number variation.

    George H Perry;Nathaniel J. Dominy;Katrina G Claw;Arthur S. Lee

  • Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

    Levi A. Garraway;Hans R. Widlund;Mark A. Rubin;Gad Getz

  • Mapping copy number variation by population-scale genome sequencing

    Ryan E. Mills;Klaudia Walter;Chip Stewart;Robert E. Handsaker

  • Preexistence and Clonal Selection of MET Amplification in EGFR Mutant NSCLC

    Alexa B. Turke;Kreshnik Zejnullahu;Yi Long Wu;Youngchul Song

  • EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer

    Jussi P. Koivunen;Craig Mermel;Kreshnik Zejnullahu;Carly Murphy

  • Copy number variation: New insights in genome diversity

    Jennifer L. Freeman;George H. Perry;Lars Feuk;Richard Redon

  • A global reference for human genetic variation

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs.

    Joshua M Korn;Finny G Kuruvilla;Steven A McCarroll;Steven A McCarroll;Alec Wysoker

  • Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

    Nick Craddock;Matthew E. Hurles;Niall Cardin;Richard D. Pearson

Frequent Co-Authors

Cynthia C. Morton
Cynthia C. Morton Brigham and Women's Hospital
Stephen W. Scherer
Stephen W. Scherer University of Toronto
Matthew E. Hurles
Matthew E. Hurles Wellcome Sanger Institute
Nigel P. Carter
Nigel P. Carter Wellcome Sanger Institute
Steven A. McCarroll
Steven A. McCarroll Harvard University
Evan E. Eichler
Evan E. Eichler University of Washington
Lars Feuk
Lars Feuk Uppsala University
Chris Tyler-Smith
Chris Tyler-Smith Wellcome Sanger Institute
Mark Gerstein
Mark Gerstein Yale University
Pasi A. Jänne
Pasi A. Jänne Harvard University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Genetics can open the door to numerous online degree programs and healthcare pathways in the United States. Many students interested in genetics also look for flexible and accelerated healthcare degrees to complement their education or enhance career prospects. For example, those on a nursing track may benefit from programs like the rn to bsn online with no clinicals, which allows registered nurses to advance their qualifications without traditional in-person clinical requirements.

If you are seeking advanced practice roles, options such as the quickest dnp program and the easiest online dnp programs can help you achieve a Doctor of Nursing Practice degree in less time or with more manageable coursework. For those looking to enter healthcare quickly, an accelerated medical assistant program can help you start a new career in just a few weeks.

Each of these pathways offers unique advantages. Whether you are aiming to broaden your knowledge in genetics or pivot to a healthcare role fast, exploring these online programs can help you match your education to your career goals.

Best Scientists Citing Charles Lee

Trending Scientists

Recently Published Articles