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Genetics
UK
2024
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Genetics and Molecular Biology
UK
2024

D-Index & Metrics

Genetics

D-Index
124
Citations
110098
World Ranking
317
National Ranking
55

Research.com Recognitions

  • 2024 - Research.com Genetics in United Kingdom Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in United Kingdom Leader Award
  • 2023 - Research.com Genetics in United Kingdom Leader Award

Overview

Chris Tyler-Smith is affiliated with the Wellcome Sanger Institute in the United Kingdom. Their primary area of research lies within biochemistry, genetics, and molecular biology, with a significant focus on genetics and molecular biology subfields. Their work spans several topics, including forensic and genetic research, genetic associations and epidemiology, forensic anthropology and bioarchaeology studies, genetic diversity and population structure, genomics and phylogenetic studies, genomics and rare diseases, and genetic and clinical aspects of sex determination and chromosomal abnormalities.

The scientist has contributed to various recent publications, including:

  • Insights into human genetic variation and population history from 929 diverse genomes, 2020, Science
  • Population Structure, Stratification, and Introgression of Human Structural Variation, 2020, Cell
  • Assembly of 43 human Y chromosomes reveals extensive complexity and variation, 2023, Nature
  • The landscape of autosomal-recessive pathogenic variants in European populations reveals phenotype-specific effects, 2021, The American Journal of Human Genetics
  • The genomic history of the Middle East, 2021, Cell

The venues where Chris Tyler-Smith frequently publishes include bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Cell, The American Journal of Human Genetics, and Science. These venues reflect the interdisciplinary nature of their research and its relevance across genetics and molecular biology fields.

Collaborations have been an integral part of Chris Tyler-Smith's research endeavors. Frequent co-authors are:

  • Yali Xue
  • Pille Hallast
  • Qasim Ayub
  • Marc Haber
  • Mohamed A. Almarri

The consistent output covering diverse topics such as forensic anthropology, population structure, and genomic history reflects a broad application of genetic and molecular biology methods. These research themes align with their main and subfields of study, indicating a deep engagement with both the fundamental and applied aspects of genetics in human populations.

Best Publications

  • A global reference for human genetic variation.

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • An integrated map of genetic variation from 1,092 human genomes

    Goncalo R Abecasis;Adam Auton;Lisa D Brooks

  • Table S2: Trans-factors and trinucleotide repeat instability Trans-factor

    Arturo López Castel;John D Cleary;Christopher E Pearson

  • Global variation in copy number in the human genome

    Richard Redon;Shumpei Ishikawa;Karen R. Fitch;Lars Feuk

  • Origins and functional impact of copy number variation in the human genome

    Donald F. Conrad;Dalila Pinto;Richard Redon;Richard Redon;Lars Feuk;Lars Feuk

  • Relative Impact of Nucleotide and Copy Number Variation on Gene Expression Phenotypes

    Barbara E. Stranger;Matthew S. Forrest;Mark Dunning;Catherine E. Ingle

  • Ancient DNA and the rewriting of human history: be sparing with Occam's razor.

    Marc Haber;Massimo Mezzavilla;Massimo Mezzavilla;Yali Xue;Chris Tyler-Smith

  • The Simons Genome Diversity Project: 300 genomes from 142 diverse populations

    Swapan Mallick;Swapan Mallick;Swapan Mallick;Heng Li;Mark Lipson;Iain Mathieson

  • A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

    Daniel G. MacArthur;Daniel G. MacArthur;Suganthi Balasubramanian;Adam Frankish;Ni Huang

  • Mapping copy number variation by population-scale genome sequencing

    Ryan E. Mills;Klaudia Walter;Chip Stewart;Robert E. Handsaker

  • The human Y chromosome: an evolutionary marker comes of age

    Mark A. Jobling;Chris Tyler-Smith

  • DNA Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis.

    Leonor Gusmão;J. Butler;Angel Carracedo;P. Gill

  • Copy number variation: New insights in genome diversity

    Jennifer L. Freeman;George H. Perry;Lars Feuk;Richard Redon

  • Human evolutionary genetics : origins, peoples & disease

    Mark A. Jobling;Matthew Hurles;Chris Tyler-Smith

  • A global reference for human genetic variation

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

    Nick Craddock;Matthew E. Hurles;Niall Cardin;Richard D. Pearson

  • IFITM3 restricts the morbidity and mortality associated with influenza

    Aaron R. Everitt;Simon Clare;Thomas Charles Pertel;Sinu P. John

  • Insights into hominid evolution from the gorilla genome sequence

    Aylwyn Scally;Julien Y. Dutheil;LaDeana W. Hillier;Gregory E. Jordan

  • DNA Commission of the International Society of Forensic Genetics: recommendations on forensic analysis using Y-chromosome STRs.

    P. Gill;C. Brenner;B. Brinkmann;Bruce Budowle

  • Y-Chromosomal Diversity in Europe Is Clinal and Influenced Primarily by Geography, Rather than by Language

    Zoë H. Rosser;Tatiana Zerjal;Matthew E. Hurles;Maarja Adojaan

Frequent Co-Authors

Yali Xue
Yali Xue Wellcome Sanger Institute
Mark A. Jobling
Mark A. Jobling University of Leicester
Matthew E. Hurles
Matthew E. Hurles Wellcome Sanger Institute
Fabrício R. Santos
Fabrício R. Santos Universidade Federal de Minas Gerais
Richard Villems
Richard Villems University of Tartu
Daniel G. MacArthur
Daniel G. MacArthur Garvan Institute of Medical Research
Peter de Knijff
Peter de Knijff Leiden University Medical Center
Richard Durbin
Richard Durbin University of Cambridge
Mait Metspalu
Mait Metspalu University of Tartu

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