Samuel W. Cushman

Overview

Best Publications

• Mechanism by Which Fatty Acids Inhibit Insulin Activation of Insulin Receptor Substrate-1 (IRS-1)-associated Phosphatidylinositol 3-Kinase Activity in Muscle *

  Chunli Yu;Yan Chen;Gary W. Cline;Dongyan Zhang

  1891
  Citations

• Hypertrophy and/or Hyperplasia: Dynamics of Adipose Tissue Growth

  Junghyo Jo;Oksana Gavrilova;Stephanie Pack;William Jou

  881
  Citations

• Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell. Time course, reversal, insulin concentration dependency, and relationship to glucose transport activity.

  E Karnieli;M J Zarnowski;P J Hissin;I A Simpson

  591
  Citations

• Hormonal Regulation of Mammalian Glucose Transport

  Ian A. Simpson;Samuel W. Cushman

  530
  Citations

• Insulin-stimulated translocation of glucose transporters in the isolated rat adipose cells: characterization of subcellular fractions.

  Ian A. Simpson;Dena R. Yver;Paul J. Hissin;Lawrence J. Wardzala

  494
  Citations

• Mechanism of insulin action on glucose transport in the isolated rat adipose cell. Enhancement of the number of functional transport systems.

  L J Wardzala;S W Cushman;L B Salans

  438
  Citations

• Cell surface labeling of glucose transporter isoform GLUT4 by bis-mannose photolabel. Correlation with stimulation of glucose transport in rat adipose cells by insulin and phorbol ester.

  G D Holman;I J Kozka;A E Clark;C J Flower

  424
  Citations

• Analysis of GLUT4 Distribution in Whole Skeletal Muscle Fibers: Identification of Distinct Storage Compartments That Are Recruited by Insulin and Muscle Contractions

  Thorkil Ploug;Bo van Deurs;Hua Ai;Samuel W. Cushman

  419
  Citations

• Insulin Stimulates Both Leptin Secretion and Production by Rat White Adipose Tissue

  Valarie A. Barr;Daniela Malide;Mary Jane Zarnowski;Simeon I. Taylor

  408
  Citations

• Enhanced proportion of small adipose cells in insulin-resistant vs insulin-sensitive obese individuals implicates impaired adipogenesis

  T. McLaughlin;A. Sherman;P. Tsao;O. Gonzalez

  405
  Citations

• Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action

  S. Satoh;H. Nishimura;A.E. Clark;I.J. Kozka

  401
  Citations

• Studies of Human Adipose Tissue. Adipose Cell Size and Number in Nonobese and Obese Patients

  Lester B. Salans;Samuel W. Cushman;Rodger E. Weismann

  392
  Citations

• Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle.

  Ji Li;Xiaoyue Hu;Pradeepa Selvakumar;Raymond R. Russell

  281
  Citations

• Normalization of blood glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose transporter gene expression.

  Barbara B. Kahn;Gerald I. Shulman;Ralph A. DeFronzo;Samuel W. Cushman

  255
  Citations

• A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents.

  Nicola Santoro;Romy Kursawe;Ebe D'Adamo;Ebe D'Adamo;Daniel J. Dykas

  232
  Citations

• A possible mechanism of insulin resistance in the rat adipose cell in streptozotocin-induced diabetes mellitus. Depletion of intracellular glucose transport systems

  E Karnieli;P J Hissin;I A Simpson;L B Salans

  226
  Citations

• Differential regulation of two glucose transporters in adipose cells from diabetic and insulin-treated diabetic rats.

  B B Kahn;M J Charron;H F Lodish;S W Cushman

  225
  Citations

• Potential mechanism of the stimulatory action of insulin on insulin-like growth factor II binding to the isolated rat adipose cell. Apparent redistribution of receptors cycling between a large intracellular pool and the plasma membrane.

  L J Wardzala;I A Simpson;M M Rechler;S W Cushman

  221
  Citations

• Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes.

  Hong Ruan;Mary Jane Zarnowski;Samuel W. Cushman;Harvey F. Lodish

  214
  Citations

• Evidence of impaired adipogenesis in insulin resistance

  Xiaolin Yang;Per-Anders Jansson;Ivan Nagaev;Maia M Jack

  210
  Citations