Andreas T Matouschek

Overview

Best Publications

• The folding of an enzyme: I. Theory of protein engineering analysis of stability and pathway of protein folding

  Alan R. Fersht;Andreas T Matouschek;Luis Serrano

  1059
  Citations

• Mapping the transition state and pathway of protein folding by protein engineering

  Andreas T Matouschek;James T. Kellis;Luis Serrano;Alan R. Fersht

  909
  Citations

• Transient folding intermediates characterized by protein engineering

  Andreas T Matouschek;James T. Kellis;Luis Serrano;Mark Bycroft

  581
  Citations

• Aggregated and monomeric α-synuclein bind to the S6′ proteasomal protein and inhibit proteasomal function

  Heather Snyder;Kwame Mensah;Catherine Theisler;Jack M. Lee

  572
  Citations

• An unstructured initiation site is required for efficient proteasome-mediated degradation.

  Sumit Prakash;Lin Tian;Kevin S. Ratliff;Rebecca E. Lehotzky

  507
  Citations

• The folding of an enzyme. II. Substructure of barnase and the contribution of different interactions to protein stability.

  Luis Serrano;James T. Kellis;Pauline Cann;Andreas Matouschek

  498
  Citations

• ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal

  Cheolju Lee;Michael P Schwartz;Sumit Prakash;Masahiro Iwakura

  496
  Citations

• Inefficient degradation of truncated polyglutamine proteins by the proteasome.

  Carina I Holmberg;Kristine E Staniszewski;Kwame N Mensah;Andreas Matouschek

  376
  Citations

• Targeting proteins for degradation

  Andreas Matouschek

  366
  Citations

• The folding of an enzyme. III. Structure of the transition state for unfolding of barnase analysed by a protein engineering procedure.

  Luis Serrano;Andreas T Matouschek;Alan R. Fersht

  338
  Citations

• Regulated protein turnover: snapshots of the proteasome in action.

  Sucharita Bhattacharyya;Houqing Yu;Carsten Mim;Andreas T Matouschek

  293
  Citations

• Detection and characterization of a folding intermediate in barnase by NMR

  Mark Bycroft;Andreas T Matouschek;James T. Kellis;Luis Serrano

  275
  Citations

• The folding of an enzyme. IV. Structure of an intermediate in the refolding of barnase analysed by a protein engineering procedure.

  Andreas Matouschek;Luis Serrano;Alan R. Fersht

  262
  Citations

• Cyclophilin catalyzes protein folding in yeast mitochondria.

  Andreas T Matouschek;Sabine Rospert;Karl Schmid;Benjamin S. Glick;Benjamin S. Glick

  251
  Citations

• Application of physical organic chemistry to engineered mutants of proteins: Hammond postulate behavior in the transition state of protein folding.

  Andreas Matouschek;Alan R. Fersht

  243
  Citations

• Protein unfolding by mitochondria. The Hsp70 import motor.

  Andreas T Matouschek;Nikolaus Pfanner;Wolfgang Voos

  231
  Citations

• The folding of an enzyme. VI. The folding pathway of barnase: comparison with theoretical models.

  Luis Serrano;Andreas T Matouschek;Alan R. Fersht

  230
  Citations

• Intrinsically disordered segments affect protein half-life in the cell and during evolution

  Robin van der Lee;Robin van der Lee;Benjamin Lang;Kai Kruse;Jörg Gsponer

  224
  Citations

• Protein unfolding — an important process in vivo?

  Andreas T Matouschek

  212
  Citations

• Lack of a Robust Unfoldase Activity Confers a Unique Level of Substrate Specificity to the Universal AAA Protease FtsH.

  Christophe Herman;Sumit Prakash;Chi Zen Lu;Andreas Matouschek

  210
  Citations