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2026

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Best Scientists

D-Index
171
Citations
103593
World Ranking
843
National Ranking
86

Chemistry

D-Index
162
Citations
89284
World Ranking
92
National Ranking
3

Alan R. Fersht publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Alan R. Fersht sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 569 publications — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Alan R. Fersht D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Alan R. Fersht sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 162 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Chemistry in United Kingdom Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Chemistry in United Kingdom Leader Award
  • 2022 - Research.com Chemistry in United Kingdom Leader Award
  • 1998 - Davy Medal, Royal Society of London (UK) In recognition for his pioneering work on the analysis of proteins by combining the methods and ideas of physical-organic chemistry with those of protein engineering thus illuminating such processes as enzymatic catalysis, protein folding, protein-protein interactions and those macromolecule interactions in general that are dominated by the chemistry of the noncovalent bond
  • 1993 - Member of the National Academy of Sciences
  • 1989 - Member of Academia Europaea
  • 1988 - Fellow of the American Academy of Arts and Sciences
  • 1983 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Alan R. Fersht is affiliated with the University of Cambridge in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine.

The main areas of study include molecular biology, oncology, physiology, immunology, and geriatrics and gerontology. Their research topics focus on:

  • PARP inhibition in cancer therapy
  • DNA repair mechanisms
  • Genomics and chromatin dynamics
  • RNA research and splicing
  • RNA modifications and cancer
  • Calcium signaling and nucleotide metabolism
  • Toxin mechanisms and immunotoxins

Frequent collaborators include Magdalena Murawska, Charlotte Blessing, Imke K. Mandemaker, Claudia Gonzalez-Leal, and G. Knobloch.

Common publication venues for their work are:

  • Molecular Cell
  • Nature Structural & Molecular Biology
  • Cell Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications

Selected recent papers include:

  • ADP-ribosyltransferases, an update on function and nomenclature, 2021, FEBS Journal
  • The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks, 2020, Molecular Cell
  • The taming of PARP1 and its impact on NAD+ metabolism, 2020, Molecular Metabolism
  • Crosstalk between Drp1 phosphorylation sites during mitochondrial remodeling and their impact on metabolic adaptation, 2021, Cell Reports
  • The histone chaperone FACT facilitates heterochromatin spreading by regulating histone turnover and H3K9 methylation states, 2021, Cell Reports

Among their recognitions, Alan R. Fersht has been awarded the Davy Medal by the Royal Society of London in 1998. The award citation highlights pioneering work in protein analysis through combining physical-organic chemistry with protein engineering, illuminating enzymatic catalysis, protein folding, protein-protein interactions, and macromolecular interactions dominated by noncovalent chemistry.

They have been elected a member or fellow of several prestigious organizations, including the National Academy of Sciences (1993), Academia Europaea (1989), the American Academy of Arts and Sciences (1988), the Royal Society, United Kingdom (1983), The Academy of Medical Sciences, United Kingdom, and the European Molecular Biology Organization (EMBO).

Best Publications

  • Enzyme structure and mechanism

    Alan Fersht

  • Structure and Mechanism in Protein Science : a guide to enzyme catalysis and protein folding

    Alan Fersht

  • Structure and Mechanism in Protein Science

    Alan Fersht

  • Hydrogen bonding and biological specificity analysed by protein engineering

    Alan R. Fersht;Jian-Ping Shi;Jack Knill-Jones;Denise M. Lowe

  • Folding of chymotrypsin inhibitor 2. 1. Evidence for a two-state transition

    Sophie E. Jackson;Alan R. Fersht

  • Awakening guardian angels: drugging the p53 pathway

    Christopher J. Brown;Sonia Lain;Chandra S. Verma;Alan R. Fersht

  • Structure and Function of a Human TAFII250 Double Bromodomain Module

    Raymond H. Jacobson;Andreas G. Ladurner;David S. King;Robert Tjian

  • The Structure of the Transition State for Folding of Chymotrypsin Inhibitor 2 Analysed by Protein Engineering Methods: Evidence for a Nucleation-condensation Mechanism for Protein Folding

    Laura S. Itzhaki;Daniel E. Otzen;Alan R. Fersht

  • The folding of an enzyme: I. Theory of protein engineering analysis of stability and pathway of protein folding

    Alan R. Fersht;Andreas T Matouschek;Luis Serrano

  • Mapping the transition state and pathway of protein folding by protein engineering

    Andreas T Matouschek;James T. Kellis;Luis Serrano;Alan R. Fersht

  • Rescuing the function of mutant p53

    Alex N. Bullock;Alan R. Fersht

  • Structural Biology of the Tumor Suppressor p53

    Andreas C. Joerger;Alan R. Fersht

  • Nucleation mechanisms in protein folding.

    Alan R Fersht

  • Energetics of protein-protein interactions: Analysis ofthe Barnase-Barstar interface by single mutations and double mutant cycles

    Gideon Schreiber;Alan R. Fersht

  • The use of double mutants to detect structural changes in the active site of the tyrosyl-tRNA synthetase (Bacillus stearothermophilus)

    Paul J. Carter;Greg Winter;Anthony J. Wilkinson;Alan R. Fersht

  • Rapid, electrostatically assisted association of proteins

    Gideon Schreiber;Alan R. Fersht

  • Optimization of rates of protein folding: the nucleation-condensation mechanism and its implications.

    Alan R. Fersht

  • PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain

    Jeremy M.R. Lambert;Jeremy M.R. Lambert;Petr Gorzov;Dimitry B. Veprintsev;Maja Söderqvist

  • The hydrogen bond in molecular recognition

    Alan R. Fersht

  • Is there a unifying mechanism for protein folding

    Valerie Daggett;Alan R. Fersht

  • Protein folding and unfolding at atomic resolution.

    Alan R. Fersht;Valerie Daggett

Frequent Co-Authors

Stefan M.V. Freund
Stefan M.V. Freund MRC Laboratory of Molecular Biology
Christopher M. Johnson
Christopher M. Johnson MRC Laboratory of Molecular Biology
Luis Serrano
Luis Serrano Centre for Genomic Regulation
Valerie Daggett
Valerie Daggett University of Washington
Ashley M. Buckle
Ashley M. Buckle Monash University
Dmitry B. Veprintsev
Dmitry B. Veprintsev University of Nottingham
Gideon Schreiber
Gideon Schreiber Weizmann Institute of Science
Andreas T Matouschek
Andreas T Matouschek The University of Texas at Austin
Jane Clarke
Jane Clarke University of Cambridge
Neil M. Ferguson
Neil M. Ferguson Imperial College London

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