Stefan M.V. Freund

Best Publications

• The solution structure of the S1 RNA binding domain: a member of an ancient nucleic acid-binding fold.

  Mark Bycroft;Tim J.P Hubbard;Mark Proctor;Stefan M.V Freund

  583
  Citations

• RNA recognition by a Staufen double‐stranded RNA‐binding domain

  Andres Ramos;Stefan Grünert;Jan Adams;David R. Micklem

  475
  Citations

• Molecular Mechanism of the Interaction between MDM2 and p53

  Oliver Schon;Assaf Friedler;Mark Bycroft;Stefan M.V Freund

  440
  Citations

• A peptide that binds and stabilizes p53 core domain: Chaperone strategy for rescue of oncogenic mutants

  Assaf Friedler;Lars O. Hansson;Dmitry B. Veprintsev;Stefan M. V. Freund

  345
  Citations

• Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome

  Andrew J. Finch;Christine Hilcenko;Nicolas Basse;Lesley F. Drynan

  319
  Citations

• Four domains of p300 each bind tightly to a sequence spanning both transactivation subdomains of p53.

  Daniel P. Teufel;Stefan M. Freund;Mark Bycroft;Alan R. Fersht

  282
  Citations

• Solution structure of a protein denatured state and folding intermediate.

  T. L. Religa;J. S. Markson;U. Mayor;U. Mayor;S. M. V. Freund

  276
  Citations

• Hot-spot mutants of p53 core domain evince characteristic local structural changes.

  Kam-Bo Wong;Brian S. DeDecker;Stefan M. V. Freund;Mark R. Proctor

  274
  Citations

• Characterization of the p53-rescue drug CP-31398 in vitro and in living cells

  Thomas M Rippin;Vladimir J N Bykov;Stefan M V Freund;Galina Selivanova

  234
  Citations

• Solution structure of p53 core domain: Structural basis for its instability

  José Manuel Pérez Cañadillas;Henning Tidow;Stefan M. V. Freund;Trevor J. Rutherford

  227
  Citations

• Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex.

  Henning Tidow;Roberto Melero;Efstratios Mylonas;Stefan M. V. Freund

  221
  Citations

• Towards a complete description of the structural and dynamic properties of the denatured state of barnase and the role of residual structure in folding

  Kam Bo Wong;Jane Clarke;Chris J. Bond;José Luis Neira

  213
  Citations

• Protein folding from a highly disordered denatured state: The folding pathway of chymotrypsin inhibitor 2 at atomic resolution

  Steven L. Kazmirski;Kam Bo Wong;Stefan M V Freund;Yee Joo Tan

  210
  Citations

• Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase

  Mark D Allen;Charles G Grummitt;Christine Hilcenko;Sandra Young Min

  203
  Citations

• Two sequence motifs from HIF-1alpha bind to the DNA-binding site of p53.

  Lars O. Hansson;Assaf Friedler;Stefan Freund;Stefan Rüdiger

  176
  Citations

• The central region of HDM2 provides a second binding site for p53

  Grace W. Yu;Stefan Rudiger;Dmitry Veprintsev;Stefan Freund

  166
  Citations

• A Comparison of the pH, Urea, and Temperature-denatured States of Barnase by Heteronuclear NMR: Implications for the Initiation of Protein Folding

  Vickery L. Arcus;Stephane Vuilleumier;Stefan M.V. Freund;Mark Bycroft

  166
  Citations

• Cold denaturation of barstar: 1H, 15N and 13C NMR assignment and characterisation of residual structure.

  Kam-Bo Wong;Stefan M.V. Freund;Alan R. Fersht

  143
  Citations

• Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne

  Tycho E. T. Mevissen;Yogesh Kulathu;Monique P.C. Mulder;Monique P.C. Mulder;Paul P. Geurink;Paul P. Geurink

  142
  Citations

• Regulation of DNA binding of p53 by its C-terminal domain.

  Richard L. Weinberg;Stefan M.V. Freund;Dmitry B. Veprintsev;Mark Bycroft

  141
  Citations