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Molecular Biology

D-Index
40
Citations
11510
World Ranking
3069
National Ranking
238

Overview

Alan J. Warren is affiliated with the University of Cambridge in the United Kingdom. Their research primarily spans the field of Biochemistry, Genetics, and Molecular Biology, with a focus on Molecular Biology, Genetics, Immunology, Oncology, and Hematology. The scope of their work includes topics such as RNA modifications and cancer, blood disorders and treatments, immunodeficiency and autoimmune disorders, RNA and protein synthesis mechanisms, RNA research and splicing, acute myeloid leukemia research, and neutropenia and cancer infections.

Their recent publications reflect an active engagement with diverse aspects of molecular and cellular biology. Notable papers include:

  • "VAMP2 regulates phase separation of α-synuclein," 2024, published in Nature Cell Biology
  • "HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis," 2021, published in Cell Stem Cell
  • "Somatic genetic rescue of a germline ribosome assembly defect," 2021, published in Nature Communications
  • "The European Guidelines on Diagnosis and Management of Neutropenia in Adults and Children: A Consensus Between the European Hematology Association and the EuNet-INNOCHRON COST Action," 2023, published in HemaSphere
  • "Pre-emptive Quality Control of a Misfolded Membrane Protein by Ribosome-Driven Effects," 2020, published in Current Biology

These publications illustrate involvement in research on ribosome assembly, protein synthesis, neurobiology, and clinical hematology guidelines.

Alan J. Warren frequently collaborates with a number of coauthors, including:

  • Shengjiang Tan
  • Christine Hilcenko
  • Alexandre Faille
  • Simone Pellegrino
  • Norberto Escudero-Urquijo

Their research outputs are often published in journals such as:

  • Nature Communications
  • Blood
  • bioRxiv (Cold Spring Harbor Laboratory)
  • HemaSphere
  • British Journal of Haematology

Best Publications

  • JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis.

    Linda M. Scott;Wei Tong;Ross L. Levine;Mike A. Scott

  • Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts

    E. Papaemmanuil;M. Cazzola;J. Boultwood;L. Malcovati

  • THE ONCOGENIC CYSTEINE-RICH LIM DOMAIN PROTEIN RBTN2 IS ESSENTIAL FOR ERYTHROID DEVELOPMENT

    Alan J. Warren;William H. Colledge;Mark B.L. Carlton;Martin J. Evans

  • An Mll–AF9 Fusion Gene Made by Homologous Recombination Causes Acute Leukemia in Chimeric Mice: A Method to Create Fusion Oncogenes

    Javier Corral;Isabelle Lavenir;Helen Impey;Alan J Warren

  • A new system for naming ribosomal proteins

    Nenad Ban;Roland Beckmann;Jamie H D Cate;Jonathan D Dinman

  • A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q– syndrome

    Jillian L Barlow;Lesley F Drynan;Duncan R Hewett;Luke R Holmes

  • The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis

    Yoshihiro Yamada;Alan J. Warren;Claire Dobson;Alan Forster

  • The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast.

    Tobias F Menne;Beatriz Goyenechea;Beatriz Goyenechea;Nuria Sánchez-Puig;Nuria Sánchez-Puig;Chi C Wong;Chi C Wong

  • Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome

    Andrew J. Finch;Christine Hilcenko;Nicolas Basse;Lesley F. Drynan

  • Protein dimerization between Lmo2 (Rbtn2) and Tal1 alters thymocyte development and potentiates T cell tumorigenesis in transgenic mice.

    R. C. Larson;I. Lavenir;T. A. Larson;R. Baer

  • The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells

    V E Valge-Archer;H Osada;A J Warren;A Forster

  • Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation.

    Cristina G. de Guzman;Alan J. Warren;Zheng Zhang;Larry Gartland

  • The Mll–AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

    C.L. Dobson;A.J. Warren;R. Pannell;A. Forster

  • The Hox11 gene is essential for cell survival during spleen development

    Terence Neil Dear;W. H. Colledge;M. B L Carlton;I. Lavenir

  • Prospective study of rabbit antithymocyte globulin and cyclosporine for aplastic anemia from the EBMT Severe Aplastic Anaemia Working Party.

    Judith C. Marsh;Andrea Bacigalupo;Hubert Schrezenmeier;Andre Tichelli

  • Defective ribosome assembly in Shwachman-Diamond syndrome

    Chi C. Wong;David Traynor;Nicolas Basse;Nicolas Basse;Robert R. Kay

  • Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase

    Mark D Allen;Charles G Grummitt;Christine Hilcenko;Sandra Young Min

  • The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp.

    Jerónimo Bravo;Zhe Li;Nancy A. Speck;Alan J. Warren

  • Mechanism of eIF6 release from the nascent 60S ribosomal subunit

    Félix Weis;Emmanuel Giudice;Mark Churcher;Li Jin

  • Tumorigenesis in mice with a fusion of the leukaemia oncogene Mll and the bacterial lacZ gene

    Claire L. Dobson;Alan J. Warren;Richard Pannell;Alan Forster

Frequent Co-Authors

Terence H. Rabbitts
Terence H. Rabbitts Institute of Cancer Research
Alan Forster
Alan Forster MRC Laboratory of Molecular Biology
Peter J. Campbell
Peter J. Campbell Wellcome Sanger Institute
Stefan M.V. Freund
Stefan M.V. Freund MRC Laboratory of Molecular Biology
Andrew N. J. McKenzie
Andrew N. J. McKenzie MRC Laboratory of Molecular Biology
Andrew J.H. Smith
Andrew J.H. Smith University of Edinburgh
Jean Donadieu
Jean Donadieu University of Paris-Saclay
Nancy A. Speck
Nancy A. Speck University of Pennsylvania
George S. Vassiliou
George S. Vassiliou University of Cambridge
Michael Costanzo
Michael Costanzo University of Toronto

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