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Biology and Biochemistry

D-Index
54
Citations
32254
World Ranking
15331
National Ranking
1207

Overview

Andrew J.H. Smith is affiliated with the University of Edinburgh in the United Kingdom. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Molecular Biology, Spectroscopy, Biophysics, Clinical Biochemistry, and Genetics.

The main topics covered in Smith's work encompass:

  • Mitochondrial Function and Pathology
  • Peroxisome Proliferator-Activated Receptors
  • Advanced Proteomics Techniques and Applications
  • Mass Spectrometry Techniques and Applications
  • Metabolomics and Mass Spectrometry Studies
  • Gene Regulatory Network Analysis
  • Single-cell and Spatial Transcriptomics

Smith has contributed to multiple publications, frequently appearing in venues such as Nature Communications, bioRxiv (Cold Spring Harbor Laboratory), Neurosurgery, BMC Biology, and Nature Structural & Molecular Biology.

Recent papers include:

  • Fast and deep phosphoproteome analysis with the Orbitrap Astral mass spectrometer, 2024, Nature Communications
  • PPTC7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy, 2023, Nature Communications
  • GATD3A, a mitochondrial deglycase with evolutionary origins from gammaproteobacteria, restricts the formation of advanced glycation end products, 2022, BMC Biology
  • On-microscope staging of live cells reveals changes in the dynamics of transcriptional bursting during differentiation, 2022, Nature Communications
  • Fast and Deep Phosphoproteome Analysis with the Orbitrap Astral Mass Spectrometer, 2023, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Smith include:

  • David J. Pagliarini
  • Jacqueline A. Sloane-Stanley
  • Christian Babbs
  • Douglas R. Higgs
  • Patrick Forny

Best Publications

  • Sequence and organization of the human mitochondrial genome

    S. Anderson;A. T. Bankier;B. G. Barrell;M. H. L. de Bruijn

  • 2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans

    R. Wilson;R. Ainscough;K. Anderson;C. Baynes

  • Impaired B and T Cell Antigen Receptor Signaling in p110δ PI 3-Kinase Mutant Mice

    Klaus Okkenhaug;Antonio Bilancio;Géraldine Farjot;Helen Priddle

  • The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways

    Armen N. Akopian;Veronika Souslova;Steven England;Steven England;Kenji Okuse

  • Altered nociception, analgesia and aggression in mice lacking the receptor for substance P.

    Carmen De Felipe;Juan F. Herrero;John A. O'Brien;James A. Palmer

  • THE ONCOGENIC CYSTEINE-RICH LIM DOMAIN PROTEIN RBTN2 IS ESSENTIAL FOR ERYTHROID DEVELOPMENT

    Alan J. Warren;William H. Colledge;Mark B.L. Carlton;Martin J. Evans

  • Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration

    Mariona Graupera;Julie Guillermet-Guibert;Lazaros C. Foukas;Li-Kun Phng

  • Endoglin, an Ancillary TGFβ Receptor, Is Required for Extraembryonic Angiogenesis and Plays a Key Role in Heart Development

    Helen M. Arthur;Jan Ure;Andrew J.H. Smith;Glenn Renforth

  • Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation

    Lazaros C. Foukas;Marc Claret;Wayne Pearce;Klaus Okkenhaug;Klaus Okkenhaug

  • Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors.

    Veronika Souslova;Paolo Cesare;Yanning Ding;Armen N. Akopian

  • Two genetically separable steps in the differentiation of thymic epithelium.

    Michael Nehls;Bruno Kyewski;Martin Messerle;Ralph Waldschütz

  • Essential role for proteinase-activated receptor-2 in arthritis

    William R. Ferrell;John C. Lockhart;Elizabeth B. Kelso;Lynette Dunning

  • The p110β isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110γ

    Julie Guillermet-Guibert;Katja Bjorklof;Katja Bjorklof;Ashreena Salpekar;Ashreena Salpekar;Cristiano Gonella;Cristiano Gonella

  • Neurofascins are required to establish axonal domains for saltatory conduction.

    Diane L. Sherman;Steven Tait;Shona Melrose;Richard Johnson

  • Genetic dissection of the α-globin super-enhancer in vivo

    Deborah Hay;Jim R. Hughes;Christian Babbs;James O.J. Davies

  • A site-directed chromosomal translocation induced in embryonic stem cells by Cre-loxP recombination.

    Smith Aj;De Sousa Ma;Kwabi-Addo B;Heppell-Parton A

  • Association between active genes occurs at nuclear speckles and is modulated by chromatin environment.

    Jill M. Brown;Joanne Green;Ricardo Pires das Neves;Helen A.C. Wallace

  • Type 2 diabetes in obese white children

    Amanda Drake;Andrew Smith;P R Betts;E C Crowne

  • Manipulating the mouse genome to engineer precise functional syntenic replacements with human sequence.

    Helen A.C. Wallace;Fatima Marques-Kranc;Melville Richardson;Francisco Luna-Crespo

  • The Mll–AF9 gene fusion in mice controls myeloproliferation and specifies acute myeloid leukaemogenesis

    C.L. Dobson;A.J. Warren;R. Pannell;A. Forster

Frequent Co-Authors

Karl-Heinz Engel
Karl-Heinz Engel Technical University of Munich
Sirpa Kärenlampi
Sirpa Kärenlampi University of Eastern Finland
Claudia Bolognesi
Claudia Bolognesi National Cancer Research Institute, UK
Laurence Castle
Laurence Castle Department for Environment Food and Rural Affairs
Lieve Herman
Lieve Herman Flemish Community
Henk van Loveren
Henk van Loveren Maastricht University
Bart Vanhaesebroeck
Bart Vanhaesebroeck University College London
Cristina Nerín
Cristina Nerín University of Zaragoza
Douglas R. Higgs
Douglas R. Higgs University of Oxford
Nathalie Gontard
Nathalie Gontard University of Montpellier

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