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Genetics

D-Index
106
Citations
47968
World Ranking
597
National Ranking
298

Overview

Eric A. Schon is affiliated with Columbia University Medical Center in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions in molecular biology and clinical biochemistry.

The scientist's work covers several interconnected topics, including:

  • Mitochondrial Function and Pathology
  • Metabolism and Genetic Disorders
  • ATP Synthase and ATPases Research
  • Amino Acid Enzymes and Metabolism
  • Alzheimer's disease research and treatments
  • Bioinformatics and Genomic Networks
  • Cholesterol and Lipid Metabolism

Eric A. Schon has co-authored frequently with several colleagues, including:

  • Estela Área-Gómez
  • Kevin Velasco
  • Delfina Larrea
  • Khushbu Kabra
  • Jorge Montesinos

Their work has appeared in a selection of publication venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science
  • Journal of Alzheimer s Disease
  • Cell Death and Disease
  • Cold Spring Harbor Perspectives in Medicine

Recent papers authored or co-authored by Eric A. Schon include:

  • "Mitochondrial disease: Replace or edit?", 2021, Science
  • "Towards a Unitary Hypothesis of Alzheimer's Disease Pathogenesis", 2024, Journal of Alzheimer s Disease
  • "Aberrant ER-mitochondria communication is a common pathomechanism in mitochondrial disease", 2024, Cell Death and Disease
  • "The contribution of mitochondria-associated ER membranes to cholesterol homeostasis", 2024, bioRxiv (Cold Spring Harbor Laboratory)
  • "The Mitochondrial Connection in Parkinson's Disease", 2025, Cold Spring Harbor Perspectives in Medicine

The scope of the research includes detailed explorations of mitochondrial functions in neurodegenerative and metabolic disorders, the communication between cellular organelles, and cholesterol metabolism. Their publications span basic molecular mechanisms and implications for diseases such as Alzheimer's and Parkinson's.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Mitochondrial respiratory-chain diseases

    Salvatore DiMauro;Eric A Schon

  • Mitochondrial DNA Deletions in Progressive External Ophthalmoplegia and Kearns-Sayre Syndrome

    Carlos T. Moraes;Salvatore Dimauro;Massimo Zeviani;Anne Lombes

  • Deletions of mitochondrial DNA in Kearns‐Sayre syndrome

    M. Zeviani;C. T. Moraes;S. DiMauro;H. Nakase

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Human mitochondrial DNA: roles of inherited and somatic mutations

    Eric A. Schon;Salvatore DiMauro;Michio Hirano

  • A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA

    Eric A. Schon;Rosario Rizzuto;Carlos T. Moraes;Hirofumi Nakase

  • mtDNA depletion with variable tissue expression: a novel genetic abnormality in mitochondrial diseases.

    Carlos T. Moraes;Sara Shanske;Hans Jürgen Tritschler;June R. Aprille

  • Mitochondrial Disorders in the Nervous System

    Salvatore DiMauro;Eric A. Schon

  • Upregulated function of mitochondria‐associated ER membranes in Alzheimer disease

    Estela Area-Gomez;Maria del Carmen Lara Castillo;Marc D Tambini;Cristina Guardia-Laguarta

  • Mitochondria: The Next (Neurode)Generation

    Eric A. Schon;Serge Przedborski

  • Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly gene

    L C Papadopoulou;C M Sue;M M Davidson;K Tanji

  • Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy

    E. Arnaudo;S. Shanske;S. DiMauro;E.A. Schon

  • Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes.

    M P King;Y Koga;M Davidson;E A Schon

  • Mitochondrial DNA mutations and pathogenesis.

    Eric A. Schon;Eduardo Bonilla;Salvatore DiMauro

  • MELAS: Clinical features, biochemistry, and molecular genetics

    E. Ciafaloni;E. Ricci;S. Shanske;C. T. Moraes

  • α-Synuclein Is Localized to Mitochondria-Associated ER Membranes

    Cristina Guardia-Laguarta;Estela Area-Gomez;Cornelia Rüb;Yuhui Liu

  • Mitochondrial DNA mutations in human disease.

    Salvatore DiMauro;Eric A. Schon

  • Neuronal degeneration and mitochondrial dysfunction

    Eric A. Schon;Giovanni Manfredi

  • Recombination via flanking direct repeats is a major cause of large-scale deletions of human mitochondrial DNA

    Shuji Mita;Rosario Rizzuto;Carlos T. Moraes;Sara Shanske

Frequent Co-Authors

Salvatore DiMauro
Salvatore DiMauro Columbia University
Eduardo Bonilla
Eduardo Bonilla Columbia University
Carlos T. Moraes
Carlos T. Moraes University of Miami
Michio Hirano
Michio Hirano Columbia University
Mercy M. Davidson
Mercy M. Davidson Columbia University
Massimo Zeviani
Massimo Zeviani University of Padua
Giovanni Manfredi
Giovanni Manfredi Cornell University
Sara Shanske
Sara Shanske Columbia University Medical Center
Rosario Rizzuto
Rosario Rizzuto University of Padua
Serge Przedborski
Serge Przedborski Columbia University

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