Bryon D. Johnson

What is he best known for?

The fields of study he is best known for:

• Immune system
• Cancer
• Cytokine

His primary areas of investigation include Immunology, Bone marrow, Immune system, Transplantation and Immune tolerance. His Immunology study incorporates themes from Blockade and Graft-versus-host disease. His work carried out in the field of Graft-versus-host disease brings together such families of science as Ex vivo and CD8, Antigen.

His research in Immune system intersects with topics in Proinflammatory cytokine, Stromal cell, Cytokine and Organoid. His Transplantation research includes themes of Haematopoiesis and Ectopic expression. Within one scientific family, Bryon D. Johnson focuses on topics pertaining to Autoimmunity under Immune tolerance, and may sometimes address concerns connected to FOXP3, Regulatory T cell and IL-2 receptor.

His most cited work include:

• Absence of regulatory T cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft versus host disease (185 citations)
• Delayed infusion of normal donor cells after MHC-matched bone marrow transplantation provides an antileukemia reaction without graft-versus-host disease (144 citations)
• Delayed infusion of immunocompetent donor cells after bone marrow transplantation breaks graft-host tolerance allows for persistent antileukemic reactivity without severe graft-versus-host disease (125 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Immunology, Cancer research, Immune system, Cytotoxic T cell and T cell. His work deals with themes such as Transplantation and Graft-versus-host disease, which intersect with Immunology. His Cancer research research also works with subjects such as

• Neuroblastoma which is related to area like CD80,
• Tumor progression, which have a strong connection to Macrophage migration inhibitory factor.

His Immune system research is multidisciplinary, relying on both Cancer and Molecular biology. His Cytotoxic T cell research incorporates themes from Cytokine, Interferon gamma and Pancreatic cancer. The concepts of his T cell study are interwoven with issues in Aspergillus fumigatus and Cell therapy.

He most often published in these fields:

• Immunology (50.00%)
• Cancer research (27.59%)
• Immune system (28.74%)

What were the highlights of his more recent work (between 2017-2021)?

• Cancer research (27.59%)
• Immunology (50.00%)
• Cytokine (12.64%)

In recent papers he was focusing on the following fields of study:

Bryon D. Johnson mainly investigates Cancer research, Immunology, Cytokine, Immune system and Internal medicine. His studies deal with areas such as CAR T-cell therapy, Peptide vaccine, Tumor microenvironment, Pd 1 blockade and Cell therapy as well as Cancer research. Virus-specific Cytotoxic T-lymphocytes, CD8, CTL* and BCL6 are among the areas of Immunology where the researcher is concentrating his efforts.

His Cytokine study combines topics from a wide range of disciplines, such as Car t cells, Cytotoxic T cell, Cell and Agonist. His work in the fields of Cytotoxic T cell, such as Adoptive cell transfer, intersects with other areas such as Gating. His Immune system study integrates concerns from other disciplines, such as Infiltration, Pancreatic cancer, CD34, Medulla and Kidney.

Between 2017 and 2021, his most popular works were:

• Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models. (93 citations)
• Multi Targeted CAR-T Cell Therapies for B-Cell Malignancies (57 citations)
• STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models (27 citations)

In his most recent research, the most cited papers focused on:

• Immune system
• Cancer
• Cytokine

His primary areas of study are Cancer research, T cell, Internal medicine, Immune system and Oncology. His Cancer research research is multidisciplinary, incorporating elements of Tumor microenvironment, Chimeric antigen receptor and Cell therapy. The various areas that Bryon D. Johnson examines in his T cell study include CD8 and Cell biology.

His Cell biology course of study focuses on Recent Thymic Emigrant and Cytotoxic T cell. His Immune system study necessitates a more in-depth grasp of Immunology. He has included themes like Steroid refractory, Car t cells, Intrathecal chemotherapy and CD20 in his Oncology study.