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Immunology

D-Index
103
Citations
37311
World Ranking
647
National Ranking
377

Medicine

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103
Citations
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World Ranking
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National Ranking
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Research.com Recognitions

  • 2021 - Distinguished Fellows of the American Association of Immunologists (AAI)

Overview

Megan Sykes is affiliated with Columbia University in the United States. Their research spans multiple fields within biomedical science, including Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology.

Their work focuses extensively on Immunology, Surgery, Transplantation, Genetics, and Molecular Biology as subfields. Main topics of research consist of T-cell and B-cell Immunology, Immune Cell Function and Interaction, Xenotransplantation and immune response, Renal Transplantation Outcomes and Treatments, Immunotherapy and Immune Responses, Diabetes and associated disorders, and Organ and Tissue Transplantation Research.

Notable recent papers by Megan Sykes include:

  • Progress in xenotransplantation: overcoming immune barriers, 2022, published in Nature Reviews Nephrology

Frequent coauthors in their research collaborations include:

  • Joshua Weiner
  • Jianing Fu
  • Mercedes Martínez
  • Tomoaki Kato
  • Nichole Danzl

Sykes has published regularly in the following venues:

  • Transplantation
  • American Journal of Transplantation
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Xenotransplantation

The scientist's contributions have been recognized by professional bodies, including receiving the Distinguished Fellows of the American Association of Immunologists (AAI) award in 2021.

Best Publications

  • Hematopoietic stem cell quiescence maintained by p21cip1/waf1.

    Tao Cheng;Neil Rodrigues;Hongmei Shen;Yong-guang Yang

  • HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression

    Tatsuo Kawai;A. Benedict Cosimi;Thomas Richard Spitzer;Nina Ellen Tolkoff-Rubin

  • Distribution and Compartmentalization of Human Circulating and Tissue-Resident Memory T Cell Subsets

    Taheri Sathaliyawala;Masaru Kubota;Naomi Yudanin;Damian Turner

  • Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

    Kazuhiko Yamada;Koji Yazawa;Akira Shimizu;Takehiro Iwanaga

  • In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche

    Joji Fujisaki;Juwell Wu;Juwell Wu;Alicia L. Carlson;Lev Silberstein

  • Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeys.

    T Kawai;A B Cosimi;R B Colvin;J Powelson

  • Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment.

    Thomas Wekerle;Thomas Wekerle;Josef Kurtz;Hiroshi Ito;Joseph V. Ronquillo

  • Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: the induction of allograft tolerance through mixed lymphohematopoietic chimerism.

    T R Spitzer;F Delmonico;N Tolkoff-Rubin;S McAfee

  • Mixed Chimerism and Transplant Tolerance

    Megan Sykes

  • Organ transplantation—how much of the promise has been realized?

    Robert I Lechler;Megan Sykes;Angus W Thomson;Laurence A Turka

  • Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning.

    Megan Sykes;Gregory L. Szot;Kirsten A. Swenson;Denise A. Pearson

  • Xenotransplantation: current status and a perspective on the future.

    Yong-Guang Yang;Megan Sykes

  • Tolerance and Cancer: Mechanisms of Tumor Evasion and Strategies for Breaking Tolerance

    Markus Y. Mapara;Megan Sykes

  • Mixed lymphohaemopoietic chimerism and graft-ver suslymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation

    Megan Sykes;Frederic Preffer;Steven McAfee;Susan L Saidman

  • Extrathymic T Cell Deletion and Allogeneic Stem Cell Engraftment Induced with Costimulatory Blockade Is Followed by Central T Cell Tolerance

    Thomas Wekerle;Mohamed H. Sayegh;Joshua Hill;Yong Zhao

  • Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: in vivo and in vitro analyses.

    Y. Fudaba;T. R. Spitzer;J. Shaffer;T. Kawai

  • Intentional induction of mixed chimerism and achievement of antitumor responses after nonmyeloablative conditioning therapy and HLA-matched donor bone marrow transplantation for refractory hematologic malignancies.

    Thomas R. Spitzer;Steven McAfee;Robert Sackstein;Christine Colby

  • Role of intrathymic clonal deletion and peripheral anergy in transplantation tolerance induced by bone marrow transplantation in mice conditioned with a nonmyeloablative regimen.

    Y Tomita;A Khan;M Sykes

  • Role for CD47-SIRPα signaling in xenograft rejection by macrophages

    Kentaro Ide;Hui Wang;Hiroyuki Tahara;Jianxiang Liu

  • Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets

    Boris Nikolic;Seika Lee;Roderick T. Bronson;Michael J. Grusby

  • Treatment of severe autoimmune disease by stem-cell transplantation

    Megan Sykes;Boris Nikolic

Frequent Co-Authors

David H. Sachs
David H. Sachs Columbia University
Yong-Guang Yang
Yong-Guang Yang Jilin University
Robert B. Colvin
Robert B. Colvin Harvard University
Frederic I. Preffer
Frederic I. Preffer Harvard University
Cosimi Ab
Cosimi Ab Harvard University
David K. C. Cooper
David K. C. Cooper University of Pittsburgh
Robert Sackstein
Robert Sackstein Florida International University
Nina Tolkoff-Rubin
Nina Tolkoff-Rubin Harvard University
Yufeng Shen
Yufeng Shen Columbia University
Jay A. Fishman
Jay A. Fishman Harvard University

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Related Online Degrees & Career Pathways

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