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Laurence A. Turka

Laurence A. Turka

D-Index & Metrics

Immunology

D-Index
111
Citations
46834
World Ranking
471
National Ranking
287

Medicine

D-Index
111
Citations
46849
World Ranking
5324
National Ranking
2875

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Laurence A. Turka is affiliated with Harvard University in the United States and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their research spans several specialized subfields including Immunology, Oncology, Transplantation, Genetics, and Surgery. The main research topics include Immune Cell Function and Interaction, CAR-T cell therapy research, Renal Transplantation Outcomes and Treatments, Immunotherapy and Immune Responses, T-cell and B-cell Immunology, Cancer Research and Treatments, and Organ Donation and Transplantation.

Turka's publications frequently appear in the following venues:

  • American Journal of Transplantation
  • Regular and Young Investigator Award Abstracts
  • The Lancet
  • Nature Immunology
  • Nature Communications

They have collaborated regularly with several co-authors, including:

  • Thomas J. Wickham
  • Sivan Elloul
  • Qizhi Tang
  • Eva C. Guinan
  • James F. Markmann

Recent papers by Laurence A. Turka include:

  • "Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials" (2020), published in The Lancet
  • "Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes" (2020), published in Nature Immunology
  • "Engineered red blood cells as an off-the-shelf allogeneic anti-tumor therapeutic" (2021), published in Nature Communications
  • "Harnessing regulatory T cells to establish immune tolerance" (2024), published in Science Translational Medicine
  • "Donor antigen-specific regulatory T cell administration to recipients of live donor kidneys: A ONE Study consortium pilot trial" (2023), published in American Journal of Transplantation

Laurence A. Turka's work often focuses on immune regulation, transplantation outcomes, and cellular therapies, reflecting their contributions across multiple high-impact studies in immune cell interaction and transplantation medicine.

The scientist has been recognized as a Member of the Association of American Physicians.

Best Publications

  • bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

    Lawrence H. Boise;Maribel González-García;Christina E. Postema;Liyun Ding

  • Deacetylase inhibition promotes the generation and function of regulatory T cells

    Ran Tao;Edwin F de Zoeten;Engin Özkaynak;Chunxia Chen

  • Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent

    Alice O. Kamphorst;Andreas Wieland;Tahseen Nasti;Shu Yang;Shu Yang

  • Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

    Jason S Stumhofer;Jonathan S Silver;Arian Laurence;Paige M Porrett

  • Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

    Yongsheng Li;Xian Chang Li;Xin Xiao Zheng;Andrew D. Wells

  • T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo.

    L A Turka;P S Linsley;H Lin;W Brady

  • Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion.

    Hua Lin;Steven F. Bolling;Peter S. Linsley;Ru Qi Wei

  • Identification of a B cell signature associated with renal transplant tolerance in humans

    Kenneth A. Newell;Adam Asare;Allan D. Kirk;Trang D. Gisler

  • The Role of T-Cell Costimulatory Activation Pathways in Transplant Rejection

    Mohamed H. Sayegh;Laurence A. Turka

  • Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation

    Valerie A. Gerriets;Rigel J. Kishton;Amanda G. Nichols;Andrew N. Macintyre

  • Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response.

    Andrew D. Wells;Hrefna Gudmundsdottir;Laurence A. Turka

  • Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

    Andrew D. Wells;Xian Chang Li;Yongsheng Li;Matthew C. Walsh

  • CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

    Mohamed H. Sayegh;Enver Akalin;Wayne W. Hancock;Mary E. Russell

  • Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question.

    Elliot J. Suchin;Peter B. Langmuir;Ed Palmer;Mohamed H. Sayegh

  • Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets.

    F. O. Nestle;Xiang-Guang Zheng;C. B. Thompson;L. A. Turka

  • Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes.

    Wayne W. Hancock;Roland Buelow;Mohamed H. Sayegh;Laurence A. Turka

  • Organ transplantation—how much of the promise has been realized?

    Robert I Lechler;Megan Sykes;Angus W Thomson;Laurence A Turka

  • Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression

    Valerie A Gerriets;Rigel J Kishton;Marc O Johnson;Marc O Johnson;Sivan Cohen

  • Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

    Wayne W. Hancock;Mohamed H. Sayegh;Xiang Guang Zheng;Robert Peach

  • Toll-Like Receptor Ligands Directly Promote Activated CD4 + T Cell Survival

    Andrew E. Gelman;Jidong Zhang;Yongwon Choi;Laurence A. Turka

Frequent Co-Authors

Mohamed H. Sayegh
Mohamed H. Sayegh American University of Beirut
Andrew D. Wells
Andrew D. Wells Children's Hospital of Philadelphia
Wayne W. Hancock
Wayne W. Hancock University of Pennsylvania
Craig B. Thompson
Craig B. Thompson Memorial Sloan Kettering Cancer Center
Terry B. Strom
Terry B. Strom Beth Israel Deaconess Medical Center
Brian J. Nickoloff
Brian J. Nickoloff Loyola University Chicago
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
Arlene H. Sharpe
Arlene H. Sharpe Harvard University
Charles B. Carpenter
Charles B. Carpenter Brigham and Women's Hospital
Yongwon Choi
Yongwon Choi University of Pennsylvania

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