Member of the Association of American Physicians
Laurence A. Turka spends much of her time researching Immunology, T cell, Cell biology, Transplantation and IL-2 receptor. Her research integrates issues of Blockade and In vivo in her study of Immunology. Her T cell study combines topics in areas such as Molecular biology and Antigen.
Her Cell biology research integrates issues from Clonal anergy, Cellular differentiation, Receptor, CTLA-4 and Major histocompatibility complex. The concepts of her Transplantation study are interwoven with issues in Bioinformatics, Immunosuppression, Allograft Tolerance, Translation and Tolerance induction. Her study in IL-2 receptor is interdisciplinary in nature, drawing from both Peripheral tolerance, Phosphatidylinositol and MHC class I.
Laurence A. Turka mainly focuses on Immunology, T cell, Cell biology, Transplantation and Immune system. Immunology is closely attributed to Blockade in her study. Her biological study spans a wide range of topics, including Cytotoxic T cell and Molecular biology.
Her Cell biology study combines topics from a wide range of disciplines, such as Receptor, IL-2 receptor, Cellular differentiation and FOXP3. Her research in IL-2 receptor intersects with topics in Peripheral tolerance and Adoptive cell transfer. Her Transplantation research incorporates themes from Haematopoiesis, Tolerance induction, In vivo and Immunotherapy.
Laurence A. Turka mostly deals with Immunology, T cell, Cell biology, Immune system and Transplantation. Immunology is a component of her Immunosuppression, Immune tolerance, IL-2 receptor, B cell and Immunotherapy studies. She studies T cell, focusing on CD28 in particular.
The various areas that Laurence A. Turka examines in her Cell biology study include Cell growth, Cellular differentiation, Regulatory T cell, FOXP3 and Glutaminolysis. Her Immune system research is multidisciplinary, incorporating elements of Inflammation, Autoantibody and Antigen. Her work is dedicated to discovering how Transplantation, Tolerance induction are connected with Confidence interval and other disciplines.
Her primary areas of study are Immunology, FOXP3, Cell biology, IL-2 receptor and Regulatory T cell. Her Immunology study typically links adjacent topics like Hematopoietic stem cell transplantation. Her studies in FOXP3 integrate themes in fields like Regulation of gene expression, Cancer research, Signal transduction and Kinase.
Laurence A. Turka interconnects Glycolysis, Receptor, Oxidative phosphorylation and Cellular differentiation in the investigation of issues within Cell biology. Research on T cell and Cytotoxic T cell is a part of her IL-2 receptor study. Laurence A. Turka has included themes like Adoptive cell transfer, Aldesleukin, Immune tolerance and Monoclonal antibody in her Regulatory T cell study.
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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
Lawrence H. Boise;Maribel González-García;Christina E. Postema;Liyun Ding.
Cell (1993)
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
Jason S Stumhofer;Jonathan S Silver;Arian Laurence;Paige M Porrett.
Nature Immunology (2007)
Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance
Yongsheng Li;Xian Chang Li;Xin Xiao Zheng;Andrew D. Wells.
Nature Medicine (1999)
Deacetylase inhibition promotes the generation and function of regulatory T cells
Ran Tao;Edwin F de Zoeten;Engin Özkaynak;Chunxia Chen.
Nature Medicine (2007)
Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion.
Hua Lin;Steven F. Bolling;Peter S. Linsley;Ru Qi Wei.
Journal of Experimental Medicine (1993)
T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo.
L A Turka;P S Linsley;H Lin;W Brady.
Proceedings of the National Academy of Sciences of the United States of America (1992)
The Role of T-Cell Costimulatory Activation Pathways in Transplant Rejection
Mohamed H. Sayegh;Laurence A. Turka.
The New England Journal of Medicine (1998)
Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response.
Andrew D. Wells;Hrefna Gudmundsdottir;Laurence A. Turka.
Journal of Clinical Investigation (1997)
Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.
Andrew D. Wells;Xian Chang Li;Yongsheng Li;Matthew C. Walsh.
Nature Medicine (1999)
CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.
Mohamed H. Sayegh;Enver Akalin;Wayne W. Hancock;Mary E. Russell.
Journal of Experimental Medicine (1995)
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