D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 92 Citations 29,019 226 World Ranking 386 National Ranking 239
Medicine D-index 97 Citations 31,161 268 World Ranking 4243 National Ranking 2399

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • T cell

Laurence A. Turka spends much of her time researching Immunology, T cell, Cell biology, Transplantation and IL-2 receptor. Her research integrates issues of Blockade and In vivo in her study of Immunology. Her T cell study combines topics in areas such as Molecular biology and Antigen.

Her Cell biology research integrates issues from Clonal anergy, Cellular differentiation, Receptor, CTLA-4 and Major histocompatibility complex. The concepts of her Transplantation study are interwoven with issues in Bioinformatics, Immunosuppression, Allograft Tolerance, Translation and Tolerance induction. Her study in IL-2 receptor is interdisciplinary in nature, drawing from both Peripheral tolerance, Phosphatidylinositol and MHC class I.

Her most cited work include:

  • bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death (2820 citations)
  • Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance (721 citations)
  • Deacetylase inhibition promotes the generation and function of regulatory T cells (696 citations)

What are the main themes of her work throughout her whole career to date?

Laurence A. Turka mainly focuses on Immunology, T cell, Cell biology, Transplantation and Immune system. Immunology is closely attributed to Blockade in her study. Her biological study spans a wide range of topics, including Cytotoxic T cell and Molecular biology.

Her Cell biology study combines topics from a wide range of disciplines, such as Receptor, IL-2 receptor, Cellular differentiation and FOXP3. Her research in IL-2 receptor intersects with topics in Peripheral tolerance and Adoptive cell transfer. Her Transplantation research incorporates themes from Haematopoiesis, Tolerance induction, In vivo and Immunotherapy.

She most often published in these fields:

  • Immunology (57.18%)
  • T cell (38.83%)
  • Cell biology (28.72%)

What were the highlights of her more recent work (between 2014-2021)?

  • Immunology (57.18%)
  • T cell (38.83%)
  • Cell biology (28.72%)

In recent papers she was focusing on the following fields of study:

Laurence A. Turka mostly deals with Immunology, T cell, Cell biology, Immune system and Transplantation. Immunology is a component of her Immunosuppression, Immune tolerance, IL-2 receptor, B cell and Immunotherapy studies. She studies T cell, focusing on CD28 in particular.

The various areas that Laurence A. Turka examines in her Cell biology study include Cell growth, Cellular differentiation, Regulatory T cell, FOXP3 and Glutaminolysis. Her Immune system research is multidisciplinary, incorporating elements of Inflammation, Autoantibody and Antigen. Her work is dedicated to discovering how Transplantation, Tolerance induction are connected with Confidence interval and other disciplines.

Between 2014 and 2021, her most popular works were:

  • Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent (413 citations)
  • Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation (348 citations)
  • Control of PI(3) kinase in Treg cells maintains homeostasis and lineage stability (254 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Internal medicine

Her primary areas of study are Immunology, FOXP3, Cell biology, IL-2 receptor and Regulatory T cell. Her Immunology study typically links adjacent topics like Hematopoietic stem cell transplantation. Her studies in FOXP3 integrate themes in fields like Regulation of gene expression, Cancer research, Signal transduction and Kinase.

Laurence A. Turka interconnects Glycolysis, Receptor, Oxidative phosphorylation and Cellular differentiation in the investigation of issues within Cell biology. Research on T cell and Cytotoxic T cell is a part of her IL-2 receptor study. Laurence A. Turka has included themes like Adoptive cell transfer, Aldesleukin, Immune tolerance and Monoclonal antibody in her Regulatory T cell study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

Lawrence H. Boise;Maribel González-García;Christina E. Postema;Liyun Ding.
Cell (1993)

4658 Citations

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

Jason S Stumhofer;Jonathan S Silver;Arian Laurence;Paige M Porrett.
Nature Immunology (2007)

840 Citations

Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

Yongsheng Li;Xian Chang Li;Xin Xiao Zheng;Andrew D. Wells.
Nature Medicine (1999)

830 Citations

Deacetylase inhibition promotes the generation and function of regulatory T cells

Ran Tao;Edwin F de Zoeten;Engin Özkaynak;Chunxia Chen.
Nature Medicine (2007)

801 Citations

Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion.

Hua Lin;Steven F. Bolling;Peter S. Linsley;Ru Qi Wei.
Journal of Experimental Medicine (1993)

793 Citations

T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo.

L A Turka;P S Linsley;H Lin;W Brady.
Proceedings of the National Academy of Sciences of the United States of America (1992)

786 Citations

The Role of T-Cell Costimulatory Activation Pathways in Transplant Rejection

Mohamed H. Sayegh;Laurence A. Turka.
The New England Journal of Medicine (1998)

719 Citations

Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response.

Andrew D. Wells;Hrefna Gudmundsdottir;Laurence A. Turka.
Journal of Clinical Investigation (1997)

698 Citations

Requirement for T-cell apoptosis in the induction of peripheral transplantation tolerance.

Andrew D. Wells;Xian Chang Li;Yongsheng Li;Matthew C. Walsh.
Nature Medicine (1999)

683 Citations

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

Mohamed H. Sayegh;Enver Akalin;Wayne W. Hancock;Mary E. Russell.
Journal of Experimental Medicine (1995)

630 Citations

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