Fellow of The Academy of Medical Sciences, United Kingdom
His main research concerns Immunology, IL-2 receptor, Transplantation, T cell and Immune system. Robert I. Lechler usually deals with Immunology and limits it to topics linked to Cytotoxic T cell and Cell biology. His studies in IL-2 receptor integrate themes in fields like Interleukin 21 and FOXP3.
The various areas that he examines in his Transplantation study include Immunosuppression, Allograft Tolerance and Bioinformatics. His T cell research incorporates elements of Epitope, Molecular biology and Receptor. Robert I. Lechler interconnects Endocrinology, Internal medicine and Histocompatibility in the investigation of issues within Immune system.
The scientist’s investigation covers issues in Immunology, Transplantation, T cell, Cell biology and Immune system. His research on Immunology frequently connects to adjacent areas such as Cytotoxic T cell. Robert I. Lechler has researched Transplantation in several fields, including Regulatory T cell, Immunosuppression, Immune tolerance and Cell therapy.
His T cell study incorporates themes from Molecular biology, Cell culture, CD8 and Major histocompatibility complex. His Cell biology course of study focuses on CD80 and CD86. His IL-2 receptor research is multidisciplinary, incorporating elements of Interleukin 21, Cancer research, FOXP3 and Adoptive cell transfer.
His primary scientific interests are in Immunology, Transplantation, Immune system, Regulatory T cell and Cell biology. His works in Immune tolerance, Adoptive cell transfer, Antigen, FOXP3 and Allorecognition are all subjects of inquiry into Immunology. His Antigen research includes elements of Transplant rejection and Antigen-presenting cell.
His Transplantation research includes themes of Tolerance induction, Immunosuppression, Major histocompatibility complex and Cell therapy. His study looks at the intersection of Major histocompatibility complex and topics like CD8 with T cell. The Cell biology study combines topics in areas such as Inflammation, Dendritic cell and IL-2 receptor.
His scientific interests lie mostly in Immunology, Transplantation, Regulatory T cell, Immune system and Immunosuppression. His work in Immune tolerance, Adoptive cell transfer, Antigen, Immunity and Humanized mouse are all subfields of Immunology research. His Transplantation research integrates issues from Cell therapy, FOXP3 and Immunotherapy.
His work carried out in the field of Immune system brings together such families of science as Microvesicles, microRNA and Cell biology. His research in Immunosuppression intersects with topics in Organ transplantation, Clinical trial, Liver transplantation and Kidney transplantation. Robert I. Lechler has included themes like T cell and Leukapheresis in his Liver transplantation study.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression
Graham M. Lord;Giuseppe Matarese;Jane K. Howard;Richard J. Baker.
Nature (1998)
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency
I. Sadaf Farooqi;Giuseppe Matarese;Graham M. Lord;Julia M. Keogh.
Journal of Clinical Investigation (2002)
Restoration of immunogenicity to passenger cell-depleted kidney allografts by the addition of donor strain dendritic cells.
R. I. Lechler;Ji R. Batchelor.
Journal of Experimental Medicine (1982)
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
Ben Afzali;Giovanna Lombardi;Robert Lechler;Graham Lord.
Clinical and Experimental Immunology (2007)
Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.
Wan Fai Ng;Phillip J. Duggan;Frederique Ponchel;Giuseppe Matarese.
Blood (2001)
Identification of a B cell signature associated with renal transplant tolerance in humans
Kenneth A. Newell;Adam Asare;Allan D. Kirk;Trang D. Gisler.
Journal of Clinical Investigation (2010)
Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice
Jane K. Howard;Graham M. Lord;Giuseppe Matarese;Silvia Vendetti.
Journal of Clinical Investigation (1999)
Galectin-1: a key effector of regulation mediated by CD4+CD25+ T cells.
Marina I. Garín;Chung-Ching Chu;Dela Golshayan;Dela Golshayan;Eva Cernuda-Morollón.
Blood (2007)
Anergic T cells as suppressor cells in vitro.
Giovanna Lombardi;Sid Sidhu;Richard Batchelor;Robert Lechler.
Science (1994)
Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans
Pervinder Sagoo;Esperanza Perucha;Birgit Sawitzki;Stefan Tomiuk.
Journal of Clinical Investigation (2010)
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