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Immunology

D-Index
71
Citations
22771
World Ranking
2286
National Ranking
206

Overview

Graham M. Lord is affiliated with the University of Manchester in the United Kingdom. Their research footprint spans extensively within the fields of Medicine and Immunology and Microbiology, with particular focus on Immunology, Surgery, Oncology, Genetics, and Molecular Biology as subfields of study.

The core topics of their work center around immune cell function and interaction, IL-33, ST2, and ILC pathways, eosinophilic esophagitis, inflammatory bowel disease, T-cell and B-cell immunology, renal transplantation outcomes and treatments, and cancer immunotherapy and biomarkers.

Frequent co-authors collaborating with Graham M. Lord include:

  • Luke B. Roberts
  • Jonathan W. Lo
  • Nick Powell
  • Peter J. Conlon
  • Gianpiero L. Cavalleri

Their work has been published across several venues, with repeated contributions to:

  • Harvard Dataverse
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Crohn's and Colitis
  • Frontiers in Immunology
  • Poster presentations

Notable papers by Graham M. Lord include:

  • "Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19," 2020, Science Immunology
  • "Regulatory T Cells Restrain Interleukin-2- and Blimp-1-Dependent Acquisition of Cytotoxic Function by CD4+ T Cells," 2020, Immunity
  • "Regulatory T-cell therapy in Crohn's disease: challenges and advances," 2020, Gut
  • "Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy," 2022, Nature Communications
  • "ILC1 drive intestinal epithelial and matrix remodelling," 2020, Nature Materials

Best Publications

  • Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

    Graham M. Lord;Giuseppe Matarese;Jane K. Howard;Richard J. Baker

  • Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency

    I. Sadaf Farooqi;Giuseppe Matarese;Graham M. Lord;Julia M. Keogh

  • Communicable Ulcerative Colitis Induced by T-bet Deficiency in the Innate Immune System

    Wendy S. Garrett;Graham M. Lord;Graham M. Lord;Graham M. Lord;Shivesh Punit;Geanncarlo Lugo-Villarino

  • The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease

    Ben Afzali;Giovanna Lombardi;Robert Lechler;Graham Lord

  • Leptin protects mice from starvation-induced lymphoid atrophy and increases thymic cellularity in ob/ob mice

    Jane K. Howard;Graham M. Lord;Giuseppe Matarese;Silvia Vendetti

  • Development of a cross-platform biomarker signature to detect renal transplant tolerance in humans

    Pervinder Sagoo;Esperanza Perucha;Birgit Sawitzki;Stefan Tomiuk

  • T-bet: a bridge between innate and adaptive immunity.

    Vanja Lazarevic;Laurie H. Glimcher;Graham M. Lord

  • Requirement for Leptin in the Induction and Progression of Autoimmune Encephalomyelitis

    Giuseppe Matarese;Antonio Di Giacomo;Veronica Sanna;Graham M. Lord

  • Nephropathy caused by Chinese herbs in the UK.

    Graham M Lord;Rajat Tagore;Terry Cook;Peter Gower

  • T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements

    Aditi Kanhere;Arnulf Hertweck;Urvashi Bhatia;M. Refik Gökmen

  • Recent developments in the transcriptional regulation of cytolytic effector cells.

    Laurie H. Glimcher;Michael J. Townsend;Brandon M. Sullivan;Graham M. Lord

  • The Transcription Factor T-bet Regulates Intestinal Inflammation Mediated by Interleukin-7 Receptor+ Innate Lymphoid Cells

    Nick Powell;Nick Powell;Nick Powell;Alan W. Walker;Emilie Stolarczyk;James B. Canavan;James B. Canavan;James B. Canavan

  • Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations

    Y. Okada;X. Sim;X. Sim;M. J. Go;J. Y. Wu;J. Y. Wu

  • Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

    Hayley G. Evans;Tesha Suddason;Ian Jackson;Leonie S. Taams

  • T-bet is required for optimal proinflammatory CD4+ T-cell trafficking.

    Graham M. Lord;Ravi M. Rao;Hyeryun Choe;Brandon M. Sullivan

  • Genetic loci influencing kidney function and chronic kidney disease

    John C Chambers;Weihua Zhang;Graham M Lord;Graham M Lord;Pim van der Harst

  • Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells.

    John Cardone;Gaelle Le Friec;Pierre Vantourout;Pierre Vantourout;Andrew Roberts;Andrew Roberts

  • The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

    Richard G. Jenner;Michael J. Townsend;Ian Jackson;Kaiming Sun

  • Absence of CC chemokine ligand 2 does not limit obesity-associated infiltration of macrophages into adipose tissue.

    Karen E. Inouye;Hang Shi;Jane K. Howard;Christine H. Daly

  • Balancing susceptibility to infection and autoimmunity: a role for leptin?

    Giuseppe Matarese;Antonio La Cava;Veronica Sanna;Graham M. Lord

  • Urothelial malignant disease and Chinese herbal nephropathy.

    Graham M Lord;Terry Cook;Volker M Arit;Heinz H Schmeiser

Frequent Co-Authors

Robert I. Lechler
Robert I. Lechler King's College London
Giovanna Lombardi
Giovanna Lombardi King's College London
Thomas T. MacDonald
Thomas T. MacDonald University of Southampton
Keith M. Channon
Keith M. Channon University of Oxford
Giuseppe Matarese
Giuseppe Matarese Yale University
Steven H. Sacks
Steven H. Sacks King's College London
Paul Elliott
Paul Elliott Imperial College London
Jeremy D. Sanderson
Jeremy D. Sanderson Guy's and St Thomas' NHS Foundation Trust
Bryan Williams
Bryan Williams University College London

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