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Marie Stiborová

Marie Stiborová

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Biology and Biochemistry
Czechia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
17776
World Ranking
6329
National Ranking
4

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Czechia Leader Award
  • 2022 - Research.com Biology and Biochemistry in Czechia Leader Award

Overview

Marie Stiborová was affiliated with Charles University in the Czech Republic. Their research contributions were primarily in the fields of Chemistry, Pharmacology, Toxicology and Pharmaceutics, and Biochemistry, Genetics and Molecular Biology. The work spanned multiple subfields including Pharmacology, Analytical Chemistry, Radiology, Nuclear Medicine and Imaging, Molecular Biology, and Cancer Research.

The scientific topics frequently addressed in their research included:

  • Nephrotoxicity and Medicinal Plants
  • Drug-Induced Hepatotoxicity and Protection
  • Heavy Metals in Plants
  • Carcinogens and Genotoxicity Assessment
  • Pharmacogenetics and Drug Metabolism
  • Toxic Organic Pollutants Impact
  • Dye analysis and toxicity

Stiborová authored several papers, indicating active engagement in studies related to carcinogenicity, genotoxicity, metabolism, and electrochemical analysis. Notable publications include:

  • Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats, 2021, International Journal of Molecular Sciences
  • Benzo[a]pyrene-Induced Genotoxicity in Rats Is Affected by Co-Exposure to Sudan I by Altering the Expression of Biotransformation Enzymes, 2021, International Journal of Molecular Sciences
  • In Vivo Metabolism of Aristolochic Acid I and II in Rats Is Influenced by Their Coexposure, 2020, Chemical Research in Toxicology
  • A study on redox reactions of the azo dye Sudan I and its hydroxylated metabolites on pyrolytic graphite and boron doped diamond electrodes to support electrochemical studies of metabolic transformations, 2023, Electrochimica Acta
  • Correction to "Site-Directed Conjugation of Antibodies to Apoferritin Nanocarrier for Targeted Drug Delivery to Prostate Cancer Cells", 2022, ACS Applied Materials & Interfaces

The researcher published most frequently in the following journals:

  • International Journal of Molecular Sciences
  • Chemical Research in Toxicology
  • Electrochimica Acta
  • ACS Applied Materials & Interfaces

Collaborations featured multiple frequent co-authors, highlighting joint research efforts with peers such as Volker M. Arlt, František Bárta, Alena Dedíková, Šárka Dušková, and Jaroslav Mráz.

Best Publications

  • Histone Deacetylase Inhibitors as Anticancer Drugs.

    Tomas Eckschlager;Johana Plch;Marie Stiborova;Jan Hrabeta

  • The role of metallothionein in oxidative stress.

    Branislav Ruttkay-Nedecky;Lukas Nejdl;Jaromir Gumulec;Ondrej Zitka

  • Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450

    Petr Hodek;Pavel Trefil;Marie Stiborová

  • Aristolochic acid as a probable human cancer hazard in herbal remedies a review

    Volker M Arlt;Marie Stiborova;Heinz H Schmeiser

  • Sudan I Is a Potential Carcinogen for Humans Evidence for Its Metabolic Activation and Detoxication by Human Recombinant Cytochrome P450 1A1 and Liver Microsomes

    Marie Stiborová;Václav Martínek;Helena Rýdlová;Petr Hodek

  • Mammalian metallothioneins: properties and functions

    Petr Babula;Petr Babula;Michal Masarik;Vojtech Adam;Vojtech Adam;Tomas Eckschlager

  • 32P-post labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy

    C A Bieler;M Stiborova;M Wiessler;J P Cosyns

  • Sanguinarine and chelerythrine: assessment of safety on pigs in ninety days feeding experiment

    Pavel Kosina;Daniela Walterová;Jitka Ulrichová;Václav Lichnovský

  • Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer

    Volker M. Arlt;Marie Stiborová;Jochen vom Brocke;Maria L. Simões

  • Anthracyclines and ellipticines as DNA-damaging anticancer drugs: recent advances.

    Rene Kizek;Vojtech Adam;Jan Hrabeta;Tomas Eckschlager

  • The anticancer agent ellipticine on activation by cytochrome P450 forms covalent DNA adducts.

    Marie Stiborová;Christian A. Bieler;Manfred Wiessler;Eva Frei

  • The epidemiology, diagnosis, and management of aristolochic acid nephropathy: a narrative review.

    M Refik Gökmen;Jean-Pierre Cosyns;Volker M Arlt;Marie Stiborová

  • The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide.

    Marie Stiborová;Jan Sejbal;Lucie Borek-Dohalská;Dagmar Aimová

  • Effect of heavy metal ions on growth and biochemical characteristics of photosynthesis of barley (Hordeum vulgare L.)

    M. Stiborova;M. Doubravova;A. Brezinova;A. Friedrich

  • Mutagenicity and DNA adduct formation of PAH, nitro-PAH, and oxy-PAH fractions of atmospheric particulate matter from São Paulo, Brazil.

    Gisela A. Umbuzeiro;Alexandre Franco;Maria Helena Martins;Fábio Kummrow

  • Human Enzymes Involved in the Metabolic Activation of Carcinogenic Aristolochic Acids: Evidence for Reductive Activation by Cytochromes P450 1A1 and 1A2

    Marie Stiborová;Eva Frei;Manfred Wiessler;Heinz H. Schmeiser

  • Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols.

    Volker M. Arlt;Marie Stiborova;Colin J. Henderson;Martin R. Osborne

  • Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice.

    Volker M. Arlt;Marie Stiborová;Colin J. Henderson;Markus Thiemann

  • Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy.

    Marie Stiborová;Eva Frei;Volker M. Arlt;Heinz H. Schmeiser

  • Effect of heavy metal ions on growth and biochemical characteristics of photosynthesis of barley and maize seedlings

    Marie Stiborová;Marta Ditrichová;Alena BŘEzinová

Frequent Co-Authors

Eva Frei
Eva Frei Charles University
Heinz H. Schmeiser
Heinz H. Schmeiser German Cancer Research Center
Volker M. Arlt
Volker M. Arlt King's College London
Rene Kizek
Rene Kizek University of Veterinary and Pharmaceutical Sciences
Vojtech Adam
Vojtech Adam Central European Institute of Technology
David H. Phillips
David H. Phillips King's College London
Manfred Wiessler
Manfred Wiessler German Cancer Research Center
Libuše Trnková
Libuše Trnková Masaryk University
Colin J. Henderson
Colin J. Henderson University of Dundee
Petr Babula
Petr Babula Masaryk University

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