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Chemistry

D-Index
57
Citations
9025
World Ranking
11364
National Ranking
829

Overview

Heinz H. Schmeiser is affiliated with the German Cancer Research Center in Germany. Their research spans across multiple scientific fields, including Medicine, Pharmacology, Toxicology and Pharmaceutics, and Chemistry.

The scientist's recent publications primarily focus on topics related to nephrotoxicity and medicinal plants, drug-induced hepatotoxicity and protection, as well as the impact of heavy metals in plants. These thematic concerns reflect a multidisciplinary approach involving toxicological and pharmacological studies.

One of the notable papers authored by Heinz H. Schmeiser is titled "Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats", published in 2021 in the International Journal of Molecular Sciences. This paper has been cited 22 times and investigates the mechanisms behind carcinogenic effects induced by combined exposure to specific aristolochic acids.

Frequent co-authors collaborating with Heinz H. Schmeiser include:

  • František Bárta
  • Alena Dedíková
  • Michaela Bebová
  • Šárka Dušková
  • Jaroslav Mráz

Research publication venues where Heinz H. Schmeiser's work commonly appears include:

  • International Journal of Molecular Sciences

The main fields of study for Heinz H. Schmeiser encompass:

  • Medicine
  • Pharmacology, Toxicology and Pharmaceutics
  • Chemistry

Subfields of study aligned with their work include:

  • Radiology, Nuclear Medicine and Imaging
  • Pharmacology
  • Analytical Chemistry

The primary topics addressed in Heinz H. Schmeiser's publications are:

  • Nephrotoxicity and Medicinal Plants
  • Drug-Induced Hepatotoxicity and Protection
  • Heavy Metals in Plants

Best Publications

  • 32P-post labelling analysis of DNA adducts formed by aristolochic acid in tissues from patients with Chinese herbs nephropathy

    C A Bieler;M Stiborova;M Wiessler;J P Cosyns

  • Aristolochic acid binds covalently to the exocyclic amino group of purine nucleotides in DNA

    Wolfgang Pfau;Heinz H. Schmeiser;Manfred Wiessler

  • Mutagenicity and DNA adduct formation of PAH, nitro-PAH, and oxy-PAH fractions of atmospheric particulate matter from São Paulo, Brazil.

    Gisela A. Umbuzeiro;Alexandre Franco;Maria Helena Martins;Fábio Kummrow

  • SOS induction of selected naturally occurring substances in Escherichia coli (SOS chromotest)

    Sebastian Kevekordes;Volker Mersch-Sundermann;Christian M Burghaus;Jan Spielberger

  • Metabolic activation of the environmental contaminant 3-nitrobenzanthrone by human acetyltransferases and sulfotransferase

    Volker M Arlt;Hansruedi Glatt;Eva Muckel;Ulrike Pabel

  • Human Enzymes Involved in the Metabolic Activation of Carcinogenic Aristolochic Acids: Evidence for Reductive Activation by Cytochromes P450 1A1 and 1A2

    Marie Stiborová;Eva Frei;Manfred Wiessler;Heinz H. Schmeiser

  • Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosols.

    Volker M. Arlt;Marie Stiborova;Colin J. Henderson;Martin R. Osborne

  • Metabolic activation of carcinogenic aristolochic acid, a risk factor for Balkan endemic nephropathy.

    Marie Stiborová;Eva Frei;Volker M. Arlt;Heinz H. Schmeiser

  • Human cytosolic enzymes involved in the metabolic activation of carcinogenic aristolochic acid: evidence for reductive activation by human NAD(P)H:quinone oxidoreductase.

    Marie Stiborová;Eva Frei;Bruno Sopko;Klára Sopková

  • Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.

    Marie Stiborová;Eva Frei;Petr Hodek;Manfred Wiessler

  • Characterization of DNA adducts formed by aristolochic acids in the target organ (forestomach) of rats by 32P-postlabelling analysis using different chromatographic procedures

    Stiborová M;Fernando Rc;Schmeiser Hh;Frei E

  • Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy

    Marie Stiborová;Eva Frei;Bruno Sopko;Manfred Wiessler

  • Identification and mutagenicity of metabolites of aristolochic acid formed by rat liver

    H.H. Schmeiser;B.L. Pool;M. Wiessler

  • Chemical and molecular basis of the carcinogenicity of Aristolochia plants.

    Heinz H Schmeiser;Marie Stiborovà;Volker M Arlt

  • Analyses of DNA adducts formed by ochratoxin A and aristolochic acid in patients with Chinese herbs nephropathy

    Volker M Arlt;Annie Pfohl-Leszkowicz;Jean-Pierre Cosyns;Heinz H Schmeiser

  • Human Enzymes Involved in the Metabolic Activation of the Environmental Contaminant 3-Nitrobenzanthrone: Evidence for Reductive Activation by Human NADPH:Cytochrome P450 Reductase

    Volker M Arlt;Marie Stiborova;Alan Hewer;Heinz H Schmeiser

  • 32P-postlabelling analysis of the DNA adducts formed by aristolochic acid I and II

    Wolfgang Pfau;Heinz H. Schmeiser;Manfred Wiessler

  • Comparison of DNA adduct formation by aristolochic acids in various in vitro activation systems by 32P-post-labelling : evidence for reductive activation by peroxidases

    H H Schmeiser;E Frei;M Wiessler;M Stiborova

  • DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer

    Marie Stiborová;Volker M Arlt;Heinz H Schmeiser

  • Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine.

    Volker M. Arlt;Heinz H. Schmeiser;Martin R. Osborne;Masanobu Kawanishi

  • DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by (32)P-postlabeling.

    Volker M. Arlt;Christian A. Bieler;Walter Mier;Manfred Wiessler

Frequent Co-Authors

Marie Stiborová
Marie Stiborová Charles University
Eva Frei
Eva Frei Charles University
Volker M. Arlt
Volker M. Arlt King's College London
Manfred Wiessler
Manfred Wiessler German Cancer Research Center
David H. Phillips
David H. Phillips King's College London
Monica Hollstein
Monica Hollstein University of Leeds
C. Roland Wolf
C. Roland Wolf University of Dundee
Colin J. Henderson
Colin J. Henderson University of Dundee
Hansruedi Glatt
Hansruedi Glatt Federal Institute for Risk Assessment
Daniel W. Nebert
Daniel W. Nebert University of Cincinnati

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