D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 89 Citations 30,675 365 World Ranking 1624 National Ranking 931

Research.com Recognitions

Awards & Achievements

1930 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • DNA
  • Enzyme
  • Gene

His primary scientific interests are in DNA, Biochemistry, Molecular biology, DNA glycosylase and Stereochemistry. His DNA study frequently involves adjacent topics like Escherichia coli. Arthur P. Grollman combines subjects such as Plasmid, Mutation, Endonuclease, Gene and DNA replication with his study of Molecular biology.

Arthur P. Grollman focuses mostly in the field of DNA replication, narrowing it down to topics relating to DNA polymerase II and, in certain cases, DNA polymerase and Cell biology. The study incorporates disciplines such as Deoxyribose, In vitro and A-DNA in addition to Stereochemistry. His work deals with themes such as Transitional cell carcinoma, Lesion, Urothelium and Guanine, which intersect with DNA damage.

His most cited work include:

  • Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG. (1866 citations)
  • TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal (860 citations)
  • Mutagenesis by 8-oxoguanine: an enemy within (687 citations)

What are the main themes of his work throughout his whole career to date?

DNA, Biochemistry, Internal medicine, Molecular biology and Aristolochic acid are his primary areas of study. His DNA study incorporates themes from Adduct and Stereochemistry. The Stereochemistry study which covers A-DNA that intersects with Duplex and Base pair.

His Internal medicine study combines topics in areas such as Gastroenterology, Endocrinology and Cardiology. Arthur P. Grollman has researched Molecular biology in several fields, including Plasmid, Mutagenesis, DNA synthesis, Escherichia coli and DNA adduct. His work in Aristolochic acid covers topics such as Carcinogen which are related to areas like Genotoxicity.

He most often published in these fields:

  • DNA (30.08%)
  • Biochemistry (25.71%)
  • Internal medicine (20.05%)

What were the highlights of his more recent work (between 2011-2021)?

  • Aristolochic acid (12.60%)
  • DNA (30.08%)
  • Carcinogen (6.94%)

In recent papers he was focusing on the following fields of study:

His main research concerns Aristolochic acid, DNA, Carcinogen, Cancer and Aristolochia. His work carried out in the field of Aristolochic acid brings together such families of science as Traditional medicine, Upper urinary tract, Pharmacology and Pathology. Arthur P. Grollman has included themes like Molecular biology and Adduct in his DNA study.

His studies in Molecular biology integrate themes in fields like Gene, Escherichia coli and Fresh Tissue. His Aristolochia research focuses on DNA damage and how it relates to In vitro and DNA repair. His biological study spans a wide range of topics, including Biophysics, Kidney metabolism and Genotoxicity.

Between 2011 and 2021, his most popular works were:

  • TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal (860 citations)
  • TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL (354 citations)
  • Aristolochic acid-associated urothelial cancer in Taiwan (261 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

Arthur P. Grollman spends much of his time researching Aristolochic acid, Carcinogen, Aristolochia, Pathology and Carcinoma. His research integrates issues of Transitional cell carcinoma, Upper urinary tract, Pharmacology and Nephrotoxicity in his study of Aristolochic acid. His Carcinogen research is multidisciplinary, relying on both Tumor suppressor gene and DNA.

His study on DNA is covered under Biochemistry. The Aristolochia study combines topics in areas such as Traditional Chinese medicine, Medicinal plants and DNA damage. His Pathology study integrates concerns from other disciplines, such as Cancer research, Urothelium and Telomerase reverse transcriptase.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG.

Shinya Shibutani;Masaru Takeshita;Arthur P. Grollman.
Nature (1991)

2697 Citations

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

Patrick J. Killela;Zachary J. Reitman;Yuchen Jiao;Chetan Bettegowda.
Proceedings of the National Academy of Sciences of the United States of America (2013)

1290 Citations

Mutagenesis by 8-oxoguanine: an enemy within

Arthur P. Grollman;Masaaki Moriya.
Trends in Genetics (1993)

997 Citations

8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.

J Tchou;H Kasai;S Shibutani;M H Chung.
Proceedings of the National Academy of Sciences of the United States of America (1991)

865 Citations

Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA.

Mark Leo Michaels;Christina Cruz;Arthur P. Grollman;Jeffrey H. Miller.
Proceedings of the National Academy of Sciences of the United States of America (1992)

738 Citations

Aristolochic acid and the etiology of endemic (Balkan) nephropathy

Arthur P. Grollman;Shinya Shibutani;Masaaki Moriya;Frederick Miller.
Proceedings of the National Academy of Sciences of the United States of America (2007)

648 Citations

Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase

Thomas A. Rosenquist;Dmitry O. Zharkov;Arthur P. Grollman.
Proceedings of the National Academy of Sciences of the United States of America (1997)

596 Citations

Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage.

L Giloni;M Takeshita;F Johnson;C Iden.
Journal of Biological Chemistry (1981)

538 Citations

Oligodeoxynucleotides containing synthetic abasic sites. Model substrates for DNA polymerases and apurinic/apyrimidinic endonucleases.

M. Takeshita;Chien-Neng Chang;F. Johnson;S. Will.
Journal of Biological Chemistry (1987)

470 Citations

TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL

Hai Yan;P.J. Killela;Z.J. Reitman;Y. Jiao.
Neuro-oncology (2014)

450 Citations

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