1930 - Fellow of John Simon Guggenheim Memorial Foundation
His primary scientific interests are in DNA, Biochemistry, Molecular biology, DNA glycosylase and Stereochemistry. His DNA study frequently involves adjacent topics like Escherichia coli. Arthur P. Grollman combines subjects such as Plasmid, Mutation, Endonuclease, Gene and DNA replication with his study of Molecular biology.
Arthur P. Grollman focuses mostly in the field of DNA replication, narrowing it down to topics relating to DNA polymerase II and, in certain cases, DNA polymerase and Cell biology. The study incorporates disciplines such as Deoxyribose, In vitro and A-DNA in addition to Stereochemistry. His work deals with themes such as Transitional cell carcinoma, Lesion, Urothelium and Guanine, which intersect with DNA damage.
DNA, Biochemistry, Internal medicine, Molecular biology and Aristolochic acid are his primary areas of study. His DNA study incorporates themes from Adduct and Stereochemistry. The Stereochemistry study which covers A-DNA that intersects with Duplex and Base pair.
His Internal medicine study combines topics in areas such as Gastroenterology, Endocrinology and Cardiology. Arthur P. Grollman has researched Molecular biology in several fields, including Plasmid, Mutagenesis, DNA synthesis, Escherichia coli and DNA adduct. His work in Aristolochic acid covers topics such as Carcinogen which are related to areas like Genotoxicity.
His main research concerns Aristolochic acid, DNA, Carcinogen, Cancer and Aristolochia. His work carried out in the field of Aristolochic acid brings together such families of science as Traditional medicine, Upper urinary tract, Pharmacology and Pathology. Arthur P. Grollman has included themes like Molecular biology and Adduct in his DNA study.
His studies in Molecular biology integrate themes in fields like Gene, Escherichia coli and Fresh Tissue. His Aristolochia research focuses on DNA damage and how it relates to In vitro and DNA repair. His biological study spans a wide range of topics, including Biophysics, Kidney metabolism and Genotoxicity.
Arthur P. Grollman spends much of his time researching Aristolochic acid, Carcinogen, Aristolochia, Pathology and Carcinoma. His research integrates issues of Transitional cell carcinoma, Upper urinary tract, Pharmacology and Nephrotoxicity in his study of Aristolochic acid. His Carcinogen research is multidisciplinary, relying on both Tumor suppressor gene and DNA.
His study on DNA is covered under Biochemistry. The Aristolochia study combines topics in areas such as Traditional Chinese medicine, Medicinal plants and DNA damage. His Pathology study integrates concerns from other disciplines, such as Cancer research, Urothelium and Telomerase reverse transcriptase.
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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG.
Shinya Shibutani;Masaru Takeshita;Arthur P. Grollman.
TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal
Patrick J. Killela;Zachary J. Reitman;Yuchen Jiao;Chetan Bettegowda.
Proceedings of the National Academy of Sciences of the United States of America (2013)
Mutagenesis by 8-oxoguanine: an enemy within
Arthur P. Grollman;Masaaki Moriya.
Trends in Genetics (1993)
8-oxoguanine (8-hydroxyguanine) DNA glycosylase and its substrate specificity.
J Tchou;H Kasai;S Shibutani;M H Chung.
Proceedings of the National Academy of Sciences of the United States of America (1991)
Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA.
Mark Leo Michaels;Christina Cruz;Arthur P. Grollman;Jeffrey H. Miller.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Aristolochic acid and the etiology of endemic (Balkan) nephropathy
Arthur P. Grollman;Shinya Shibutani;Masaaki Moriya;Frederick Miller.
Proceedings of the National Academy of Sciences of the United States of America (2007)
Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase
Thomas A. Rosenquist;Dmitry O. Zharkov;Arthur P. Grollman.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage.
L Giloni;M Takeshita;F Johnson;C Iden.
Journal of Biological Chemistry (1981)
Oligodeoxynucleotides containing synthetic abasic sites. Model substrates for DNA polymerases and apurinic/apyrimidinic endonucleases.
M. Takeshita;Chien-Neng Chang;F. Johnson;S. Will.
Journal of Biological Chemistry (1987)
TERT PROMOTER MUTATIONS OCCUR FREQUENTLY IN GLIOMAS AND A SUBSET OF TUMORS DERIVED FROM CELLS WITH LOW RATES OF SELF-RENEWAL
Hai Yan;P.J. Killela;Z.J. Reitman;Y. Jiao.
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