D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 95 Citations 36,675 269 World Ranking 1233 National Ranking 744

Research.com Recognitions

Awards & Achievements

2018 - Fellow, National Academy of Inventors

2005 - Member of the National Academy of Sciences

1994 - Fellow of the American Academy of Arts and Sciences

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Enzyme
  • DNA

Susan Band Horwitz mainly investigates Tubulin, Microtubule, Paclitaxel, Cell biology and Biochemistry. Susan Band Horwitz has included themes like Molecular biology, Biophysics, Vinca alkaloid and Binding site in her Tubulin study. Her Binding site research includes themes of Amino acid and Stereochemistry.

In her study, Cell cycle, A549 cell and Discodermolide is strongly linked to Mitosis, which falls under the umbrella field of Microtubule. The Paclitaxel study combines topics in areas such as Plasma protein binding, Pharmacology, Mechanism of action, GTP' and Drug resistance. Her Cell biology research integrates issues from Cell culture and Colchicine.

Her most cited work include:

  • Promotion of microtubule assembly in vitro by taxol (2909 citations)
  • Taxol stabilizes microtubules in mouse fibroblast cells. (1611 citations)
  • Mechanism of action of taxol (648 citations)

What are the main themes of her work throughout her whole career to date?

Her primary areas of investigation include Microtubule, Tubulin, Biochemistry, Molecular biology and Cell culture. Her Microtubule study contributes to a more complete understanding of Cell biology. Her Tubulin research is multidisciplinary, relying on both Taxane, Microtubule-associated protein, Plasma protein binding, Photoaffinity labeling and GTP'.

Susan Band Horwitz usually deals with Molecular biology and limits it to topics linked to DNA and Camptothecin. She combines subjects such as Phenotype, Multiple drug resistance and Glycoprotein with her study of Cell culture. Her Discodermolide study combines topics from a wide range of disciplines, such as Cancer research and Eleutherobin.

She most often published in these fields:

  • Microtubule (28.31%)
  • Tubulin (23.53%)
  • Biochemistry (23.53%)

What were the highlights of her more recent work (between 2009-2020)?

  • Tubulin (23.53%)
  • Cancer research (12.50%)
  • Microtubule (28.31%)

In recent papers she was focusing on the following fields of study:

Her primary scientific interests are in Tubulin, Cancer research, Microtubule, Molecular biology and Discodermolide. Tubulin is a subfield of Cell biology that Susan Band Horwitz studies. Susan Band Horwitz interconnects Cancer cell, Cancer, Protein kinase B, Bioinformatics and Ovarian carcinoma in the investigation of issues within Cancer research.

Her Microtubule research includes elements of Photoaffinity labeling, Biophysics, Biochemistry and Protein subunit. Her research in Molecular biology intersects with topics in Vinblastine, Cell culture, Peptide sequence and Antibody. Her Discodermolide study incorporates themes from Cell, A549 cell, Senescence, Paclitaxel and Ixabepilone.

Between 2009 and 2020, her most popular works were:

  • Insulin-like Growth Factor 2 Expression Modulates Taxol Resistance and Is a Candidate Biomarker for Reduced Disease-Free Survival in Ovarian Cancer (72 citations)
  • Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes (61 citations)
  • Nature as a remarkable chemist: a personal story of the discovery and development of Taxol. (58 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Her main research concerns Microtubule, Tubulin, Discodermolide, Cell biology and Molecular biology. Her study connects Biophysics and Microtubule. The study incorporates disciplines such as Plasma protein binding, Biochemistry and Binding site in addition to Tubulin.

Susan Band Horwitz studied Discodermolide and Cell that intersect with Molecular Pharmacology, Transcription factor and Cell growth. Her Cell biology research is multidisciplinary, incorporating elements of Computational biology and A549 cell. Her studies in Molecular biology integrate themes in fields like Cancer research, Protein kinase B, Signal transduction and Ovarian carcinoma, Ovarian cancer.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Promotion of microtubule assembly in vitro by taxol

Peter B. Schiff;Jane Fant;Susan B. Horwitz.
Nature (1979)

4826 Citations

Taxol stabilizes microtubules in mouse fibroblast cells.

Peter B. Schiff;Susan Band Horwitz.
Proceedings of the National Academy of Sciences of the United States of America (1980)

2588 Citations

Mechanism of action of taxol

Susan Band Horwitz.
Trends in Pharmacological Sciences (1992)

1012 Citations

Studies With RP 56976 (Taxotere): A Semisynthetic Analogue of Taxol

Israel Ringel;Susan Band Horwitz.
Journal of the National Cancer Institute (1991)

937 Citations

Mechanisms of Taxol resistance related to microtubules.

George A Orr;Pascal Verdier-Pinard;Hayley McDaid;Susan Band Horwitz.
Oncogene (2003)

790 Citations

Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes.

Maria Kavallaris;Dennis Y.S. Kuo;Catherine A. Burkhart;Donna Lee Regl.
Journal of Clinical Investigation (1997)

699 Citations

Taxol: an antimitotic agent with a new mechanism of action

James J. Manfredi;Susan Band Horwitz.
Pharmacology & Therapeutics (1984)

637 Citations

Activated bleomycin. A transient complex of drug, iron, and oxygen that degrades DNA.

R M Burger;J Peisach;S B Horwitz.
Journal of Biological Chemistry (1981)

626 Citations

Taxol binds to cellular microtubules.

James J. Manfredi;Jerome Parness;Susan Band Horwitz.
Journal of Cell Biology (1982)

545 Citations

EFFECT OF CHELATING AGENTS AND METAL IONS ON THE DEGRADATION OF DNA BY BLEOMYCIN

Edward A. Sausville;Jack Peisach;Susan B. Horwitz.
Biochemistry (1978)

526 Citations

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