World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
97
Citations
38871
World Ranking
1736
National Ranking
965

Research.com Recognitions

  • 2018 - Fellow, National Academy of Inventors
  • 2005 - Member of the National Academy of Sciences
  • 1994 - Fellow of the American Academy of Arts and Sciences

Overview

Susan Band Horwitz is affiliated with the Albert Einstein College of Medicine in the United States. Their research spans several interconnected fields, including biochemistry, genetics and molecular biology, and medicine. More specifically, their subfields of study include cell biology, oncology, physiology, and molecular biology.

The scientist's primary topics of work focus on microtubule and mitosis dynamics, telomeres, telomerase and senescence, genomics and chromatin dynamics, drug transport and resistance mechanisms, and cancer treatment and pharmacology.

Recent publications reflect these interests and include:

  • Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence, 2020, Molecular Pharmacology
  • Utilization of Photoaffinity Labeling to Investigate Binding of Microtubule Stabilizing Agents to P-Glycoprotein and β-Tubulin, 2022, Journal of Natural Products

Frequent coauthors in their research work include:

  • Hayley M. McDaid
  • Boying Guo
  • Alicia Rodriguez-Gabin
  • A.E. Prota
  • Tobias Mühlethaler

Publication venues where the scientist has contributed work include:

  • Molecular Pharmacology
  • Journal of Natural Products

The scientist has received several awards, including:

  • Fellow, National Academy of Inventors (2018)
  • Member of the National Academy of Sciences (2005)
  • Fellow of the American Academy of Arts and Sciences (1994)

Best Publications

  • Promotion of microtubule assembly in vitro by taxol

    Peter B. Schiff;Jane Fant;Susan B. Horwitz

  • Taxol stabilizes microtubules in mouse fibroblast cells.

    Peter B. Schiff;Susan Band Horwitz

  • Mechanism of action of taxol

    Susan Band Horwitz

  • Studies With RP 56976 (Taxotere): A Semisynthetic Analogue of Taxol

    Israel Ringel;Susan Band Horwitz

  • Mechanisms of Taxol resistance related to microtubules.

    George A Orr;Pascal Verdier-Pinard;Hayley McDaid;Susan Band Horwitz

  • Taxol binds to polymerized tubulin in vitro

    J Parness;SB Horwitz

  • Taxol-resistant epithelial ovarian tumors are associated with altered expression of specific beta-tubulin isotypes.

    Maria Kavallaris;Dennis Y.S. Kuo;Catherine A. Burkhart;Donna Lee Regl

  • Taxol: an antimitotic agent with a new mechanism of action

    James J. Manfredi;Susan Band Horwitz

  • Activated bleomycin. A transient complex of drug, iron, and oxygen that degrades DNA.

    R M Burger;J Peisach;S B Horwitz

  • Taxol binds to cellular microtubules.

    James J. Manfredi;Jerome Parness;Susan Band Horwitz

  • Mechanisms of taxol-induced cell death are concentration dependent

    Keila Enitt Torres;Susan Band Horwitz

  • EFFECT OF CHELATING AGENTS AND METAL IONS ON THE DEGRADATION OF DNA BY BLEOMYCIN

    Edward A. Sausville;Jack Peisach;Susan B. Horwitz

  • Taxol (paclitaxel): mechanisms of action.

    Horwitz Sb

  • Taxol assembles tubulin in the absence of exogenous guanosine 5'-triphosphate or microtubule-associated proteins.

    Peter B. Schiff;Susan Band Horwitz

  • Properties and products of the degradation of DNA by bleomycin and iron(II)

    Edward A. Sausville;Roland W. Stein;Jack Peisach;Susan B. Horwitz

  • Taxol: mechanisms of action and resistance.

    Horwitz Sb;Cohen D;Rao S;Ringel I

  • A role for ferrous ion and oxygen in the degradation of DNA by bleomycin.

    Edward A. Sausville;Jack Peisach;Susan B. Horwitz

  • 3'-(p-azidobenzamido)taxol photolabels the N-terminal 31 amino acids of beta-tubulin.

    Srinivasa Rao;N. E. Krauss;J. M. Heerding;C. S. Swindell

  • Progesterone interacts with P-glycoprotein in multidrug-resistant cells and in the endometrium of gravid uterus.

    Chia-Ping Huang Yang;S. G. Depinho;L. M. Greenberger;R. J. Arceci

  • Insights into the mechanism of microtubule stabilization by Taxol

    Hui Xiao;Pascal Verdier-Pinard;Narcis Fernandez-Fuentes;Berta Burd

Frequent Co-Authors

Jack Peisach
Jack Peisach Albert Einstein College of Medicine
Amos B. Smith
Amos B. Smith University of Pennsylvania
Iwao Ojima
Iwao Ojima Stony Brook University
Arthur P. Grollman
Arthur P. Grollman Stony Brook University
Samuel J. Danishefsky
Samuel J. Danishefsky Columbia University
Ting-Chao Chou
Ting-Chao Chou Memorial Sloan Kettering Cancer Center
Andras Fiser
Andras Fiser Albert Einstein College of Medicine
David E. Cohen
David E. Cohen Weill Cornell Medical College in Qatar
Stanley M. Crain
Stanley M. Crain Albert Einstein College of Medicine

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