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Biology and Biochemistry

D-Index
63
Citations
26169
World Ranking
9978
National Ranking
4370

Overview

Mary Ann Jordan is affiliated with the University of California, Santa Barbara in the United States. Their research spans multiple fields within medicine and life sciences, particularly focusing on cancer treatment, pharmacology, and microbial infections.

The main fields of study in Mary Ann Jordan's work include Medicine and Biochemistry, Genetics and Molecular Biology. They have contributed to subfields such as Oncology, Cell Biology, Hematology, Ecology, and Endocrinology. The topics they frequently explore relate to Cancer Treatment and Pharmacology, Microtubule and mitosis dynamics, Multiple Myeloma Research and Treatments, Bacteriophages and microbial interactions, Infections and bacterial resistance, as well as Microbial infections and disease research.

Mary Ann Jordan's recent publications illustrate the breadth of their research interests. Notable papers include:

  • "Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy," published in 2021 in Toxicology and Applied Pharmacology
  • "Bacteriophage Therapy of Multidrug-resistant Achromobacter in an 11-Year-old Boy With Cystic Fibrosis Assessed by Metagenome Analysis," published in 2023 in The Pediatric Infectious Disease Journal

The venues where these works appeared include Toxicology and Applied Pharmacology and The Pediatric Infectious Disease Journal, reflecting a focus on both pharmacological mechanisms and infectious disease treatment.

Mary Ann Jordan frequently collaborates with other researchers, with coauthors including Rebecca L. Best, Nichole E. LaPointe, Olga Azarenko, Herb P. Miller, and Christine Genualdi. These collaborations indicate a multidisciplinary approach drawing from various expertise to address complex biomedical problems.

Best Publications

  • Microtubules as a target for anticancer drugs.

    Mary Ann Jordan;Leslie Wilson

  • Microtubule-binding agents: a dynamic field of cancer therapeutics

    Charles Dumontet;Mary Ann Jordan

  • Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

    Mary Ann Jordan;Robert J. Toso;Doug Thrower;Leslie Wilson

  • Mitotic Block Induced in HeLa Cells by Low Concentrations of Paclitaxel (Taxol) Results in Abnormal Mitotic Exit and Apoptotic Cell Death

    Jordan Ma;Wendell K;Gardiner S;Derry Wb

  • Microtubules and actin filaments: dynamic targets for cancer chemotherapy

    Mary Ann Jordan;Leslie Wilson

  • Taxol suppresses dynamics of individual microtubules in living human tumor cells

    Anne Marie C. Yvon;Patricia Wadsworth;Mary Ann Jordan

  • Mechanism of Inhibition of Cell Proliferation by Vinca Alkaloids

    Mary Ann Jordan;Douglas Thrower;Leslie Wilson

  • Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis.

    M.A. Jordan;D. Thrower;L. Wilson

  • The primary antimitotic mechanism of action of the synthetic halichondrin E7389 is suppression of microtubule growth

    Mary Ann Jordan;Kathryn Kamath;Tapas Manna;Tatiana Okouneva

  • Substoichiometric binding of taxol suppresses microtubule dynamics

    W B Derry;L Wilson;M A Jordan

  • Eribulin Binds at Microtubule Ends to a Single Site on Tubulin To Suppress Dynamic Instability

    Jennifer A. Smith;Leslie Wilson;Olga Azarenko;Xiaojie Zhu

  • Resistance to Taxol in lung cancer cells associated with increased microtubule dynamics

    A. Gonçalves;D. Braguer;K. Kamath;L. Martello

  • How do microtubule-targeted drugs work? An overview.

    Mary Ann Jordan;Kathy Kamath

  • βIII-Tubulin Induces Paclitaxel Resistance in Association with Reduced Effects on Microtubule Dynamic Instability

    Kathy Kamath;Leslie Wilson;Fernando Cabral;Mary Ann Jordan

  • Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine.

    Robert J. Toso;Mary Ann Jordan;Kevin W. Farrell;Brian Matsumoto

  • Taxol Differentially Modulates the Dynamics of Microtubules Assembled from Unfractionated and Purified β-Tubulin Isotypes†

    Derry Wb;Wilson L;Khan Ia;Luduena Rf

  • Microtubule dynamics: taking aim at a moving target

    Leslie Wilson;Mary Ann Jordan

  • Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase.

    Tatiana Okouneva;Olga Azarenko;Leslie Wilson;Bruce A. Littlefield

  • Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: implications for chemotherapy-induced peripheral neuropathy.

    Nichole E. LaPointe;Gerardo A. Morfini;Scott T. Brady;Stuart C. Feinstein

  • Maytansine and Cellular Metabolites of Antibody-Maytansinoid Conjugates Strongly Suppress Microtubule Dynamics by Binding to Microtubules

    Manu Lopus;Emin Oroudjev;Leslie Wilson;Sharon Wilhelm

Frequent Co-Authors

Leslie Wilson
Leslie Wilson University of California, San Francisco
Richard F. Ludueña
Richard F. Ludueña The University of Texas Health Science Center at San Antonio
Dulal Panda
Dulal Panda Indian Institute of Technology Bombay
Barbara S. Slusher
Barbara S. Slusher Johns Hopkins University School of Medicine
Susan Band Horwitz
Susan Band Horwitz Albert Einstein College of Medicine
Gerardo Morfini
Gerardo Morfini University of Illinois at Chicago
Scott T. Brady
Scott T. Brady University of Illinois at Chicago
Patricia Wadsworth
Patricia Wadsworth University of Massachusetts Amherst
William H. Gerwick
William H. Gerwick University of California, San Diego
Melvyn Little
Melvyn Little German Cancer Research Center

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