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Biology and Biochemistry

D-Index
59
Citations
10335
World Ranking
12754
National Ranking
5438

Overview

Richard F. Ludueña is affiliated with The University of Texas Health Science Center at San Antonio in the United States. Their research primarily falls within the field of Biochemistry, Genetics and Molecular Biology, with a focus on several related subfields including Molecular Biology, Cell Biology, Cellular and Molecular Neuroscience, Endocrinology, and Biophysics.

The scientist's work encompasses several key research topics, notably:

  • Microtubule and mitosis dynamics
  • Protist diversity and phylogeny
  • Photoreceptor and optogenetics research
  • Nuclear Structure and Function
  • Cellular transport and secretion
  • Photosynthetic Processes and Mechanisms
  • Vibrio bacteria research studies

Richard F. Ludueña has contributed to notable publications spanning various well-regarded venues. These include:

  • Frontiers in Cell and Developmental Biology (2 publications)
  • Frontiers in Molecular Neuroscience (1 publication)
  • Open Access Government (1 publication)
  • PLoS ONE (1 publication)

Among recent papers authored by Ludueña are:

  • "Possible Roles of Specific Amino Acids in β-Tubulin Isotypes in the Growth and Maintenance of Neurons: Novel Insights From Cephalopod Mollusks," 2022, Frontiers in Molecular Neuroscience
  • "Nuclear βII-Tubulin and its Possible Utility in Cancer Diagnosis, Prognosis and Treatment," 2022, Frontiers in Cell and Developmental Biology
  • "A novel approach to cancer chemotherapy," 2025, Open Access Government

Frequent co-authors collaborating with Ludueña include:

  • Jack A. Tuszyński
  • Consuelo Walss-Bass
  • Anna Portyanko
  • Jiayan Guo
  • I-Tien Yeh

The research conducted by Ludueña often intersects with cellular and molecular processes that impact cancer biology, neuronal growth, and cellular transport mechanisms. The works encompass both experimental and computational approaches, as demonstrated by topics ranging from amino acid roles in tubulin isotypes to potential therapeutic discoveries against infectious agents.

Best Publications

  • Multiple forms of tubulin: different gene products and covalent modifications.

    Richard F. Ludueña

  • Structure of tubulin at 6.5 Å and location of the taxol-binding site

    Eva Nogales;Sharon Grayer Wolf;Israr A. Khan;Richard F. Ludueña

  • Microtubule dynamics in vitro are regulated by the tubulin isotype composition.

    Dulal Panda;Herbert P. Miller;Asok Banerjee;Richard F. Ludueña

  • Are tubulin isotypes functionally significant.

    Richard F. Ludueña

  • Taxol Differentially Modulates the Dynamics of Microtubules Assembled from Unfractionated and Purified β-Tubulin Isotypes†

    Derry Wb;Wilson L;Khan Ia;Luduena Rf

  • Increased microtubule assembly in bovine brain tubulin lacking the type III isotype of beta-tubulin.

    Asok Banerjee;Mary Carmen Roach;Phyllis Trcka;Richard F. Ludueña

  • Tubulin sulfhydryl groups as probes and targets for antimitotic and antimicrotubule agents.

    Richard F. Luduena;Mary C. Roach

  • Structure of the tubulin dimer.

    R F Ludueńa;E M Shooter;L Wilson

  • A monoclonal antibody against the type II isotype of beta-tubulin. Preparation of isotypically altered tubulin.

    A Banerjee;M C Roach;K A Wall;M A Lopata

  • Isolation and Partial Characterization of α - and β -Tubulin from Outer Doublets of Sea-Urchin Sperm and Microtubules of Chick-Embryo Brain

    Richard F. Luduena;Dowo O. Woodward

  • Kinetics of colchicine binding to purified beta-tubulin isotypes from bovine brain.

    Asok Banerjee;Richard F. Luduena

  • Preparation of a monoclonal antibody specific for the class IV isotype of beta-tubulin. Purification and assembly of alpha beta II, alpha beta III, and alpha beta IV tubulin dimers from bovine brain.

    Asok Banerjee;Mary Carmen Roach;Phyllis Trcka;Richard F. Luduena

  • Structural differences between brain beta 1- and beta 2-tubulins: implications for microtubule assembly and colchicine binding.

    M Little;R F Ludueña

  • Removal of beta III isotype enhances taxol induced microtubule assembly.

    Qing Lu;Richard F. Luduena

  • The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms.

    April L. Risinger;Evelyn M. Jackson;Lisa A. Polin;Gregory L. Helms

  • Expression of class III beta tubulin in non-small cell lung cancer is correlated with resistance to taxane chemotherapy.

    Charles Dumontet;Sylvie Isaac;Pierre Jean Souquet;Françoise Bejui-Thivolet

  • Interaction of ustiloxin a with bovine brain tubulin

    Richard F. Ludueña;Mary Carmen Roach;Veena Prasad;Mohua Banerjee

  • A hypothesis on the origin and evolution of tubulin.

    Richard F. Ludueña

  • In vitro analysis of microtubule assembly of isotypically pure tubulin dimers. Intrinsic differences in the assembly properties of alpha beta II, alpha beta III, and alpha beta IV tubulin dimers in the absence of microtubule-associated proteins.

    Qing Lu;Richard F. Luduena

  • Interaction of tubulin with drugs and alkylating agents. 2. Effects of colchicine, podophyllotoxin, and vinblastine on the alkylation of tubulin.

    Richard F. Ludueña;Mary Carmen Roach

Frequent Co-Authors

Melvyn Little
Melvyn Little German Cancer Research Center
Mary Ann Jordan
Mary Ann Jordan University of California, Santa Barbara
Paul M. Horowitz
Paul M. Horowitz The University of Texas Health Science Center at San Antonio
George R. Pettit
George R. Pettit Arizona State University
Dimitri V. Nanopoulos
Dimitri V. Nanopoulos Texas A&M University
Thomas H. MacRae
Thomas H. MacRae Dalhousie University
Paul N. Hoffman
Paul N. Hoffman Johns Hopkins University
Ernest Hamel
Ernest Hamel National Institutes of Health
John C. Lee
John C. Lee The University of Texas Health Science Center at San Antonio
Jesús Avila
Jesús Avila Centro de Biología Molecular Severo Ochoa

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