What is he best known for?
The fields of study he is best known for:
- Organic chemistry
- Biochemistry
- Enzyme
George R. Pettit mostly deals with Stereochemistry, Biochemistry, Combretastatin, Tubulin and Bryostatin 1.
His Stereochemistry study combines topics in areas such as Biological activity, In vitro and Cell culture, Human cancer.
George R. Pettit interconnects Prodrug and Chemical synthesis in the investigation of issues within Combretastatin.
His work deals with themes such as Vinblastine, Natural product, Mitosis and Colchicine, which intersect with Tubulin.
His studies deal with areas such as Bryostatin, Molecular biology, Pharmacology and Protein kinase A as well as Bryostatin 1.
His Cell growth study integrates concerns from other disciplines, such as Inhibitory postsynaptic potential and Botany.
His most cited work include:
- Isolation and structure of the strong cell growth and tubulin inhibitor combretastatin A-4 (598 citations)
- Combretastatin A-4, an agent that displays potent and selective toxicity toward tumor vasculature (589 citations)
- Isolation and Structure of Bryostatin 1 (495 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Stereochemistry, Organic chemistry, Biochemistry, Cell culture and Bryostatin 1.
His Stereochemistry research incorporates themes from Sponge, Combretastatin, Human cancer, Biological activity and Chemical synthesis.
His study looks at the relationship between Combretastatin and topics such as Prodrug, which overlap with Phosphate.
His research in Biochemistry tackles topics such as Tubulin which are related to areas like Vinblastine.
His research integrates issues of Cancer cell, Cell growth and Cytotoxicity in his study of Cell culture.
The concepts of his Bryostatin 1 study are interwoven with issues in Bryostatin, Molecular biology, Immunology and Pharmacology.
He most often published in these fields:
- Stereochemistry (42.92%)
- Organic chemistry (16.23%)
- Biochemistry (16.34%)
What were the highlights of his more recent work (between 1999-2020)?
- Stereochemistry (42.92%)
- Biochemistry (16.34%)
- Combretastatin (8.17%)
In recent papers he was focusing on the following fields of study:
Stereochemistry, Biochemistry, Combretastatin, Prodrug and Chemical synthesis are his primary areas of study.
His biological study spans a wide range of topics, including Cell culture, Cell growth, Sponge and Biological activity, Pharmacognosy.
In Biochemistry, he works on issues like Cancer cell, which are connected to Growth inhibition and Growth inhibitory.
George R. Pettit works mostly in the field of Combretastatin, limiting it down to topics relating to Pharmacology and, in certain cases, In vivo, as a part of the same area of interest.
His Prodrug research is multidisciplinary, incorporating elements of Medicinal chemistry, Phosphate, Organic chemistry, Sodium and Combinatorial chemistry.
His Chemical synthesis research incorporates elements of Wittig reaction, Stereoisomerism, Ether, Structure–activity relationship and Narciclasine.
Between 1999 and 2020, his most popular works were:
- Inhibition of cyclin-dependent kinases, GSK-3β and CK1 by hymenialdisine, a marine sponge constituent (340 citations)
- Microplate Alamar Blue Assay for Staphylococcus epidermidis Biofilm Susceptibility Testing (245 citations)
- Density functional study on the structural conformations and intramolecular charge transfer from the vibrational spectra of the anticancer drug combretastatin‐A2 (193 citations)
In his most recent research, the most cited papers focused on:
- Organic chemistry
- Enzyme
- Biochemistry
His primary areas of investigation include Stereochemistry, Combretastatin, Biochemistry, Biological activity and Chemical synthesis.
George R. Pettit interconnects Tubulin, Pharmacognosy and Cell growth in the investigation of issues within Stereochemistry.
His Combretastatin study incorporates themes from Prodrug, Pharmacology, Resveratrol, Phosphate and In vivo.
His Biochemistry study combines topics from a wide range of disciplines, such as Mitosis and Cell biology.
His Biological activity research is multidisciplinary, relying on both Cancer cell, Combretum caffrum, Benzophenone and Cis–trans isomerism.
His Chemical synthesis research incorporates themes from Wittig reaction, Combretastatin A-4, Cytotoxicity, Structure–activity relationship and Amine gas treating.
This overview was generated by a machine learning system which analysed the scientist’s
body of work. If you have any feedback, you can
contact us
here.
