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Chemistry

D-Index
96
Citations
52161
World Ranking
1502
National Ranking
577

Overview

Michael R. Boyd is affiliated with the University of South Alabama in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with a focus on Oncology, Molecular Biology, Immunology, Polymers and Plastics, and Pharmacology.

Their scholarly contributions include exploration into topics such as Peptidase Inhibition and Analysis, Biochemical and Molecular Research, Pancreatic and Hepatic Oncology Research, Phosphodiesterase function and regulation, Inflammatory mediators and NSAID effects, Mast cells and histamine, and Cancer Immunotherapy and Biomarkers.

Among their recent publications are:

  • PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/β-catenin transcription, cancer cell growth, and tumor immunity (2020, Drug Discovery Today)
  • A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer (2024, Cancer Research)
  • A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer (2023, bioRxiv (Cold Spring Harbor Laboratory))
  • CHARACTERIZATION AND CORRELATION OF THE NETWORK CHAIN DENSITY TO THE PROPERTIES OF FLUOROELASTOMER RUBBER (2020, Rubber Chemistry and Technology)
  • A potent and selective pan-RAS inhibitor, ADT-1004, targeting complex KRAS mutations for pancreatic cancer (2024, Journal of Clinical Oncology)

Their frequent coauthors include:

  • Gary A. Piazza
  • Donald J. Buchsbaum
  • Adam B. Keeton
  • Yulia Maxuitenko
  • Jeremy B. Foote

Michael R. Boyd has contributed to multiple publications in venues such as:

  • Journal of Clinical Oncology
  • Drug Discovery Today
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Rubber Chemistry and Technology

Best Publications

  • New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

    Philip Skehan;Ritsa Storeng;Dominic Scudiero;Anne Monks

  • Evaluation of a Soluble Tetrazolium/Formazan Assay for Cell Growth and Drug Sensitivity in Culture Using Human and Other Tumor Cell Lines

    Dominic A. Scudiero;Robert H. Shoemaker;Kenneth D. Paull;Anne Monks

  • Some Practical Considerations and Applications of the National Cancer Institute In Vitro Anticancer Drug Discovery Screen

    Michael R. Boyd;Kenneth D. Paull

  • Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm

    K. D. Paull;R. H. Shoemaker;L. Hodes;A. Monks

  • Comparison of In Vitro Anticancer-Drug-Screening Data Generated With a Tetrazolium Assay Versus a Protein Assay Against a Diverse Panel of Human Tumor Cell Lines

    L. V. Rubinstein;R. H. Shoemaker;K. D. Paull;R. M. Simon

  • New Soluble-Formazan Assay for HIV-1 Cytopathic Effects: Application to High-Flux Screening of Synthetic and Natural Products for AIDS-Antiviral Activity

    Owen S. Weislow;Rebecca Kiser;Donald L. Fine;John Bader

  • Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development.

    M R Boyd;K R Gustafson;J B McMahon;R H Shoemaker

  • The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum.

    Yoel Kashman;Kirk R. Gustafson;Richard W. Fuller;John H. Cardellina

  • Antineoplastic Agents. 291. Isolation and Synthesis of Combretastatins A-4, A-5, and A-6

    George R. Pettit;Sheo Bux Singh;Michael R. Boyd;Michael R. Boyd;Ernest Hamel;Ernest Hamel

  • Isolation and Characterization of Griffithsin, a Novel HIV-inactivating Protein, from the Red Alga Griffithsia sp.

    Toshiyuki Mori;Barry R. O'Keefe;Raymond C. Sowder;Scott Bringans

  • AIDS-Antiviral Sulfolipids From Cyanobacteria (Blue-Green Algae)

    Kirk R. Gustafson;John H. Cardellina;Richard W. Fuller;Owen S. Weislow

  • Circulins A and B. Novel human immunodeficiency virus (HIV)-inhibitory macrocyclic peptides from the tropical tree Chassalia parvifolia.

    Kirk R. Gustafson;Raymond C. Sowder;Louis E. Henderson;Ian C. Parsons

  • Salicylihalamides A and B, Novel Cytotoxic Macrolides from the Marine Sponge Haliclona sp.

    Karen L. Erickson;John A. Beutler;John H. Cardellina;Michael R. Boyd

  • Antineoplastic agents 322. synthesis of combretastatin A-4 prodrugs.

    G. R. Pettit;C. Temple;V. L. Narayanan;Ravi Varma

  • Antineoplastic agents. 379. Synthesis of phenstatin phosphate.

    George R. Pettit;Brian Toki;Delbert L. Herald;Pascal Verdier-Pinard

  • Biochemical Mechanisms in Chemical-Induced Lung Injury: Roles of Metabolic Activation

    Michael R. Boyd;H. P. Witschi

  • Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against human immunodeficiency virus in vitro.

    Robert Vince;Mei Hua;Jay Brownell;Susan Daluge

  • The guttiferones, HIV-inhibitory benzophenones from Symphonia globulifera, Garcinia livingstonei, Garcinia ovalifolia and Clusia rosea

    Kirk R. Gustafson;John W. Blunt;Murray H.G. Munro;Richard W. Fuller

  • PAPUAMIDES A-D, HIV-INHIBITORY AND CYTOTOXIC DEPSIPEPTIDES FROM THE SPONGES THEONELLA MIRABILIS AND THEONELLA SWINHOEI COLLECTED IN PAPUA NEW GUINEA

    R.W.M. van Soest;P.W. Ford;K.R. Gustafson;T.C. Mc Kee

  • Anti-HIV michellamines from Ancistrocladus korupensis.

    Michael R. Boyd;Yali F. Hallock;John H. CardellinaII;Kirk P. Manfredi

  • A Potent Novel Anti-HIV Protein from the Cultured Cyanobacterium Scytonema varium†

    Heidi R. Bokesch;Barry R. O'keefe;Tawnya C. Mckee;Lewis K. Pannell

  • Isolation and structure of the cell growth inhibitory constituents from the Western Pacific marine sponge Axinella sp.

    George R. Pettit;Cherry L. Herald;Michael R. Boyd;Michael R. Boyd;John E. Leet

  • Novel alkaloids from the tropical plant Ancistrocladus abbreviatus inhibit cell killing by HIV-1 and HIV-2.

    Kirk P. Manfredi;John W. Blunt;John H. Cardellina;James B. McMahon

Frequent Co-Authors

George R. Pettit
George R. Pettit Arizona State University
Kirk R. Gustafson
Kirk R. Gustafson National Institutes of Health
John H. Cardellina
John H. Cardellina Montana State University
Gerhard Bringmann
Gerhard Bringmann University of Würzburg
Jean M. Schmidt
Jean M. Schmidt Arizona State University
John A. Beutler
John A. Beutler National Institutes of Health
Robert H. Shoemaker
Robert H. Shoemaker National Institutes of Health
James B. McMahon
James B. McMahon National Institutes of Health
Vijayalakshmi Ravindranath
Vijayalakshmi Ravindranath Indian Institute of Science
Rodney F. Minchin
Rodney F. Minchin University of Queensland

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