What is he best known for?
The fields of study he is best known for:
- Enzyme
- Organic chemistry
- Biochemistry
His primary scientific interests are in Stereochemistry, Biological activity, Biochemistry, Pharmacognosy and In vitro.
His Stereochemistry research focuses on Lactone in particular.
As part of the same scientific family, John H. Cardellina usually focuses on Biological activity, concentrating on Cytotoxicity and intersecting with Cytotoxic T cell.
His work on Amino acid and Pterocarpan as part of general Biochemistry research is often related to Edman degradation and Triterpene, thus linking different fields of science.
The concepts of his Pharmacognosy study are interwoven with issues in Calophyllum, Established cell line, Pyranocoumarins and Halomon.
His In vitro research incorporates elements of Quinoline, Heteronuclear single quantum coherence spectroscopy and Alkaloid.
His most cited work include:
- The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum. (446 citations)
- Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity (355 citations)
- AIDS-Antiviral Sulfolipids From Cyanobacteria (Blue-Green Algae) (265 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Stereochemistry, Biochemistry, Sponge, Biological activity and In vitro.
His Stereochemistry research includes elements of Cytotoxic T cell, Pharmacognosy, Organic chemistry and Cytotoxicity.
His Cytotoxic T cell study combines topics in areas such as In vivo and Tunicate.
His Cytotoxicity study combines topics from a wide range of disciplines, such as Sesquiterpene and Two-dimensional nuclear magnetic resonance spectroscopy.
His work on Enzyme, Topoisomerase and DNA damage as part of general Biochemistry study is frequently linked to Sterol, therefore connecting diverse disciplines of science.
John H. Cardellina has included themes like Lactone and Tumor cells in his Sponge study.
He most often published in these fields:
- Stereochemistry (56.98%)
- Biochemistry (19.77%)
- Sponge (15.70%)
What were the highlights of his more recent work (between 2003-2019)?
- Stereochemistry (56.98%)
- Biochemistry (19.77%)
- DNA damage (2.91%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Stereochemistry, Biochemistry, DNA damage, Botany and In vitro.
His biological study spans a wide range of topics, including Biological activity, Cytotoxic T cell, Structure–activity relationship and Organic chemistry.
His Biological activity study incorporates themes from Azole, Sponge, Two-dimensional nuclear magnetic resonance spectroscopy and Aspergillus flavus.
Many of his studies on Biochemistry apply to Candida albicans as well.
His work on Rubiaceae as part of general Botany research is frequently linked to Active components, Crossosoma bigelovii and Histone deacetylase inhibitor, bridging the gap between disciplines.
The concepts of his In vitro study are interwoven with issues in Sephadex, Drug discovery, Alkaloid and Alangiaceae.
Between 2003 and 2019, his most popular works were:
- Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity (355 citations)
- Ethnobotany and Drug Discovery: The Experience of the US National Cancer Institute (94 citations)
- Identification of a Bis-guanylhydrazone [4,4′-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a Novel Chemotype for Inhibition of Chk2 Kinase (53 citations)
In his most recent research, the most cited papers focused on:
- Organic chemistry
- Enzyme
- Botany
John H. Cardellina mostly deals with Biochemistry, Antifungal, Pterocarpan, Botany and Pharmacognosy.
His work on Biological activity, Protein–protein interaction, Protein structure and Cell cycle checkpoint as part of general Biochemistry research is frequently linked to FLAG-tag, thereby connecting diverse disciplines of science.
His Antifungal research is multidisciplinary, incorporating elements of Fungi imperfecti, Aspergillus flavus and Candida albicans.
His work carried out in the field of Pterocarpan brings together such families of science as Antibacterial activity and Microbiology.
His study in the field of Hildegardia barteri is also linked to topics like Hildegardiol.
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