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D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
35270
World Ranking
6497
National Ranking
3025

Overview

Robert H. Shoemaker is affiliated with the National Institutes of Health in the United States. Their research primarily covers medicine, biochemistry, genetics and molecular biology, and immunology and microbiology, reflecting a broad engagement with biomedical sciences.

The scientist's work spans several key subfields including immunology, molecular biology, oncology, pathology and forensic medicine, and cancer research. These areas highlight a focus on understanding disease mechanisms and immune system functions.

Among the main topics addressed in their research are immunotherapy and immune responses, genetic factors in colorectal cancer, cancer immunotherapy and biomarkers, cancer genomics and diagnostics, cancer research and treatments, immune cells in cancer, and SARS-CoV-2 and COVID-19 research.

Frequent collaborators in their research include Shizuko Sei, Lígia A. Pinto, Jason D. Marshall, Chelsea Sanders, and Simone Difilippantonio.

The most common venues for publication are Cancer Research, Cancer Prevention Research, Vaccine, bioRxiv (Cold Spring Harbor Laboratory), and Cancers. This indicates a consistent presence in journals related to oncology and immunology.

Recent papers published include:

  • Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model, 2021, Gastroenterology
  • Targeting Glutamine Metabolism to Enhance Immunoprevention of EGFR-Driven Lung Cancer, 2022, Advanced Science
  • Naproxen chemoprevention promotes immune activation in Lynch syndrome colorectal mucosa, 2020, Gut
  • Clinical grade ACE2 as a universal agent to block SARS-CoV -2 variants, 2022, EMBO Molecular Medicine
  • WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells, 2021, Nature Communications

Best Publications

  • Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell Lines

    Anne Monks;Dominic Scudiero;Philip Skehan;Robert Shoemaker

  • Feasibility of Drug Screening with Panels of Human Tumor Cell Lines Using a Microculture Tetrazolium Assay

    Michael C. Alley;Dominic A. Scudiero;Anne Monks;Miriam L. Hursey

  • Evaluation of a Soluble Tetrazolium/Formazan Assay for Cell Growth and Drug Sensitivity in Culture Using Human and Other Tumor Cell Lines

    Dominic A. Scudiero;Robert H. Shoemaker;Kenneth D. Paull;Anne Monks

  • The NCI60 human tumour cell line anticancer drug screen

    Robert H. Shoemaker

  • Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm

    K. D. Paull;R. H. Shoemaker;L. Hodes;A. Monks

  • Comparison of In Vitro Anticancer-Drug-Screening Data Generated With a Tetrazolium Assay Versus a Protein Assay Against a Diverse Panel of Human Tumor Cell Lines

    L. V. Rubinstein;R. H. Shoemaker;K. D. Paull;R. M. Simon

  • New Soluble-Formazan Assay for HIV-1 Cytopathic Effects: Application to High-Flux Screening of Synthetic and Natural Products for AIDS-Antiviral Activity

    Owen S. Weislow;Rebecca Kiser;Donald L. Fine;John Bader

  • Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development.

    M R Boyd;K R Gustafson;J B McMahon;R H Shoemaker

  • Identification of Small Molecule Inhibitors of Hypoxia-inducible Factor 1 Transcriptional Activation Pathway

    Annamaria Rapisarda;Badarch Uranchimeg;Dominic A. Scudiero;Mike Selby

  • Echinomycin, a Small-Molecule Inhibitor of Hypoxia-Inducible Factor-1 DNA-Binding Activity

    Dehe Kong;Eun Jung Park;Andrew G. Stephen;Maura Calvani

  • Topoisomerase I-mediated inhibition of hypoxia-inducible factor 1: mechanism and therapeutic implications.

    Annamaria Rapisarda;Badarch Uranchimeg;Olivier Sordet;Yves Pommier

  • Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo.

    Joell J. Gills;Jaclyn LoPiccolo;Junji Tsurutani;Robert H. Shoemaker

  • Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against human immunodeficiency virus in vitro.

    Robert Vince;Mei Hua;Jay Brownell;Susan Daluge

  • Application of a Human Tumor Colony-forming Assay to New Drug Screening

    R H Shoemaker;M K Wolpert-DeFilippes;D H Kern;M M Lieber

  • Overlapping phenotypes of multidrug resistance among panels of human cancer-cell lines

    Miguel A. Izquierdo;Robert H. Shoemaker;Marcel J. Flens;George L. Scheffer

  • Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer

    Mariangela Russo;Sandra Misale;Ge Wei;Giulia Siravegna

  • ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer.

    Filippo Pietrantonio;Federica Di Nicolantonio;Alexa B Schrock;Jeeyun Lee

  • Novel Effect of Antihelminthic Niclosamide on S100A4-Mediated Metastatic Progression in Colon Cancer

    Ulrike Sack;Wolfgang Walther;Dominic Scudiero;Mike Selby

  • Schedule-dependent Inhibition of Hypoxia-inducible Factor-1α Protein Accumulation, Angiogenesis, and Tumor Growth by Topotecan in U251-HRE Glioblastoma Xenografts

    Annamaria Rapisarda;Jessica Zalek;Melinda Hollingshead;Till Braunschweig

  • The Metastasis-Associated Gene S100A4 Is a Novel Target of β-catenin/T-cell Factor Signaling in Colon Cancer

    Ulrike Stein;Ulrike Stein;Franziska Arlt;Franziska Arlt;Wolfgang Walther;Wolfgang Walther;Janice Smith

Frequent Co-Authors

Dominic A. Scudiero
Dominic A. Scudiero Science Applications International Corporation (United States)
Michael R. Boyd
Michael R. Boyd University of South Alabama
John H. Cardellina
John H. Cardellina Montana State University
Michael R. Boyd
Michael R. Boyd National Cancer Institute
Peter M. Schlag
Peter M. Schlag Charité - University Medicine Berlin
Yves Pommier
Yves Pommier National Institutes of Health
Ronald A. Lubet
Ronald A. Lubet National Institutes of Health
Edward A. Sausville
Edward A. Sausville University of Maryland, Baltimore
Ming You
Ming You Medical College of Wisconsin
John A. Beutler
John A. Beutler National Institutes of Health

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