James B. McMahon

Overview

Best Publications

• New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

  Philip Skehan;Ritsa Storeng;Dominic Scudiero;Anne Monks

  14833
  Citations

• Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development.

  M R Boyd;K R Gustafson;J B McMahon;R H Shoemaker

  884
  Citations

• The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum.

  Yoel Kashman;Kirk R. Gustafson;Richard W. Fuller;John H. Cardellina

  826
  Citations

• Isolation and Characterization of Griffithsin, a Novel HIV-inactivating Protein, from the Red Alga Griffithsia sp.

  Toshiyuki Mori;Barry R. O'Keefe;Raymond C. Sowder;Scott Bringans

  502
  Citations

• Initial studies on the cellular pharmacology of 2′,3′-dideoxycytidine, an inhibitor of HTLV-III infectivity

  David A. Cooney;Maha Dalal;Hiroaki Mitsuya;James B. McMahon

  450
  Citations

• Circulins A and B. Novel human immunodeficiency virus (HIV)-inhibitory macrocyclic peptides from the tropical tree Chassalia parvifolia.

  Kirk R. Gustafson;Raymond C. Sowder;Louis E. Henderson;Ian C. Parsons

  428
  Citations

• Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae

  Barry R. O'Keefe;Barbara Giomarelli;Dale L. Barnard;Shilpa R. Shenoy

  373
  Citations

• Oligosaccharide and glycoprotein microarrays as tools in HIV glycobiology; glycan-dependent gp120/protein interactions.

  Eddie W Adams;Daniel M Ratner;Heidi R Bokesch;James B McMahon

  342
  Citations

• Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide component

  Barry R. O'Keefe;Fakhrieh Vojdani;Viviana Buffa;Robin J. Shattock

  328
  Citations

• The guttiferones, HIV-inhibitory benzophenones from Symphonia globulifera, Garcinia livingstonei, Garcinia ovalifolia and Clusia rosea

  Kirk R. Gustafson;John W. Blunt;Murray H.G. Munro;Richard W. Fuller

  308
  Citations

• Anti-HIV michellamines from Ancistrocladus korupensis.

  Michael R. Boyd;Yali F. Hallock;John H. CardellinaII;Kirk P. Manfredi

  297
  Citations

• A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1

  Kirk R. Gustafson;John H. Cardellina;James B. McMahon;Robert J. Gulakowski

  268
  Citations

• Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones

  Scott R. Budihas;Inna Gorshkova;Sergei Gaidamakov;Antony Wamiru

  255
  Citations

• Novel alkaloids from the tropical plant Ancistrocladus abbreviatus inhibit cell killing by HIV-1 and HIV-2.

  Kirk P. Manfredi;John W. Blunt;John H. Cardellina;James B. McMahon

  236
  Citations

• Novel intrapulmonary model for orthotopic propagation of human lung cancers in athymic nude mice.

  Theodore L. McLemore;Mark C. Liu;Penny C. Blacker;Marybelle Gregg

  231
  Citations

• Identification of an Inhibitor of the EWS-FLI1 Oncogenic Transcription Factor by High-Throughput Screening

  Patrick J. Grohar;Girma M. Woldemichael;Laurie B. Griffin;Arnulfo Mendoza

  227
  Citations

• Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific manner.

  Anders J. Bolmstedt;Barry R. O'Keefe;Shilpa R. Shenoy;James B. McMahon

  224
  Citations

• A semiautomated multiparameter approach for anti-HIV drug screening.

  Robert J. Gulakowski;James B. McMahon;Patricia G. Staley;Robert A. Moran

  213
  Citations

• Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1

  Sang-Moon Yun;Tinoush Moulaei;Dan Lim;Jeong K. Bang

  204
  Citations

• Domain-Swapped Structure of the Potent Antiviral Protein Griffithsin and Its Mode of Carbohydrate Binding

  Natasza E. Ziółkowska;Barry R. O'Keefe;Toshiyuki Mori;Charles Zhu

  201
  Citations