World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
81
Citations
23064
World Ranking
965
National Ranking
513

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Nancy H. Colburn was affiliated with the National Institutes of Health in the United States. Their research contributions spanned several areas within biochemistry, genetics, and molecular biology, with a particular focus on molecular biology, cellular and molecular neuroscience, and biophysics.

Colburn's work covered multiple topics, including:

  • Nerve injury and regeneration
  • Protein degradation and inhibitors
  • Pluripotent stem cells research
  • Cell image analysis techniques
  • Viral infectious diseases and gene expression in insects
  • Bioluminescence and chemiluminescence research

Their recent publications include:

  • "PDCD4 regulates axonal growth by translational repression of neurite growth-related genes and is modulated during nerve injury responses," published in 2020 in RNA
  • "The Untapped Potential of Genetically Engineered Mouse Models in Chemoprevention Research: Opportunities and Challenges," published in 2020 at UNC Libraries

Frequent co-authors with whom Colburn collaborated include:

  • Andrés Di Paolo
  • Guillermo Eastman
  • Raquel Mesquita-Ribeiro
  • Joaquina Farías
  • Andrew Macklin

Colburn's publications appeared mainly in venues such as RNA and UNC Libraries, reflecting the interdisciplinary nature of their work spanning both experimental molecular biology and broader biomedical research.

In 2012, Nancy H. Colburn was recognized as a Fellow of the American Association for the Advancement of Science (AAAS), an acknowledgment related to their contributions to scientific research.

Best Publications

  • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer.

    I. A. Asangani;S. A.K. Rasheed;D. A. Nikolova;J. H. Leupold

  • MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene.

    Z. Lu;M. Liu;V. Stribinskis;C. M. Klinge

  • S6K1- and ßTRCP-Mediated Degradation of PDCD4 Promotes Protein Translation and Cell Growth

    N. Valerio Dorrello;Angelo Peschiaroli;Daniele Guardavaccaro;Nancy H. Colburn

  • The Transformation Suppressor Pdcd4 Is a Novel Eukaryotic Translation Initiation Factor 4A Binding Protein That Inhibits Translation

    Hsin Sheng Yang;Aaron P. Jansen;Anton A. Komar;Xiaojing Zheng

  • Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: A randomized placebo-controlled, double-blind trial

    Frank L. Meyskens;Christine E. McLaren;Daniel Pelot;Sharon Fujikawa-Brooks

  • Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion.

    Matthew R. Young;Jian-Jian Li;Jian-Jian Li;Mercedes Rincón;Richard A. Flavell

  • Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.

    Zigang Dong;Michael J. Birrer;Rebecca G. Watts;Lynn M. Matrisian

  • Tumour promoter induces anchorage independence irreversibly

    Nancy H. Colburn;Brigitte F. Former;Katherine A. Nelson;Stuart H. Yuspa

  • Epidermal expression of the translation inhibitor programmed cell death 4 suppresses tumorigenesis.

    Aaron P. Jansen;Corinne E. Camalier;Nancy H. Colburn

  • Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation

    Joan L. Cmarik;Hongzhong Min;Glenn Hegamyer;Shuning Zhan

  • Activator protein 1 (AP-1)– and nuclear factor κB (NF-κB)–dependent transcriptional events in carcinogenesis

    Tin-Chen Hsu;Matthew R Young;Joan Cmarik;Nancy H Colburn

  • Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures

    Stuart H. Yuspa;Ulrike Lichti;Theresa Ben;Elroy Patterson

  • p130/pRb2 has growth suppressive properties similar to yet distinctive from those of retinoblastoma family members pRb and p107.

    Pp Claudio;Cm Howard;A Baldi;A De Luca

  • AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells

    Lori R. Bernstein;Nancy H. Colburn

  • Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure–activity relationship and molecular mechanisms

    De Xing Hou;Keiko Kai;Jian-Jian Li;Shigang Lin

  • p53 Translocation to Mitochondria Precedes Its Nuclear Translocation and Targets Mitochondrial Oxidative Defense Protein-Manganese Superoxide Dismutase

    Yunfeng Zhao;Luksana Chaiswing;Joyce M. Velez;Ines Batinic-Haberle

  • Loss of programmed cell death 4 expression marks adenoma-carcinoma transition, correlates inversely with phosphorylated protein kinase B, and is an independent prognostic factor in resected colorectal cancer

    Giridhar Mudduluru;Fabian Medved;Rainer Grobholz;Camela Jost

  • A Novel Function of the MA-3 Domains in Transformation and Translation Suppressor Pdcd4 Is Essential for Its Binding to Eukaryotic Translation Initiation Factor 4A

    Hsin-Sheng Yang;Myung-Haing Cho;Halina Zakowicz;Glenn Hegamyer

  • A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-κB or ODC transactivation

    Hsin-Sheng Yang;Aaron P Jansen;Rajalakshmi Nair;Keiichi Shibahara

  • Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion.

    Nancy H. Colburn;Edmund J. Wendel;Gina Abruzzo

Frequent Co-Authors

Yi Sun
Yi Sun Zhejiang University
Zigang Dong
Zigang Dong University of Minnesota
James B. McMahon
James B. McMahon National Institutes of Health
Jian Jian Li
Jian Jian Li University of California, Davis
Paul S. Albert
Paul S. Albert National Institutes of Health
John A. Beutler
John A. Beutler National Institutes of Health
Kirk R. Gustafson
Kirk R. Gustafson National Institutes of Health
Myung-Haing Cho
Myung-Haing Cho Seoul National University
Larry W. Oberley
Larry W. Oberley University of Iowa
Michael I. Lerman
Michael I. Lerman National Institutes of Health

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Best Scientists Citing Nancy H. Colburn