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Genetics and Molecular Biology
China
2024

D-Index & Metrics

Molecular Biology

D-Index
111
Citations
41600
World Ranking
361
National Ranking
210

Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in China Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in China Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in China Leader Award

Overview

Zigang Dong is affiliated with the University of Minnesota in the United States and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans numerous subfields, focusing mainly on Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Cancer Research, and Surgery.

The research topics covered by Dong include Lung Cancer Treatments and Mutations, Cancer-related Molecular Pathways, RNA modifications and cancer, Cancer Mechanisms and Therapy, PI3K/AKT/mTOR signaling in cancer, Cancer-related molecular mechanisms research, and Epigenetics and DNA Methylation.

Recent publications by Dong's group illustrate areas of investigation and collaboration. These include:

  • Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy, 2021, Molecular Cancer
  • Ubiquitination and deubiquitination in cancer: from mechanisms to novel therapeutic approaches, 2024, Molecular Cancer
  • Unraveling the complexity of STAT3 in cancer: molecular understanding and drug discovery, 2024, Journal of Experimental & Clinical Cancer Research
  • Challenge and countermeasures for EGFR targeted therapy in non-small cell lung cancer, 2021, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
  • Integrins in cancer: Emerging mechanisms and therapeutic opportunities, 2023, Pharmacology & Therapeutics

Frequent coauthors that collaborate with Dong include Kangdong Liu, Kyle Vaughn Laster, Yanan Jiang, Mee-Hyun Lee, and Hanyong Chen.

Dong publishes regularly in several scientific journals, with the most frequent venues including Oncogene, Cancer Research, SSRN Electronic Journal, Molecular Cancer, and Journal of Experimental & Clinical Cancer Research. Their contributions to these journals reflect a significant focus on cancer-related biochemistry and molecular mechanisms.

Best Publications

  • Post-translational modification of p53 in tumorigenesis

    Ann M. Bode;Zigang Dong

  • AKt as a therapeutic target for cancer

    Mengqiu Song;Ann M. Bode;Zigang Dong;Mee Hyun Lee

  • Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase.

    Qing Bai She;Ann M. Bode;Wei-Ya Ma;Nan Yue Chen

  • Resveratrol suppresses cell transformation and induces apoptosis through a p53-dependent pathway.

    Chuanshu Huang;Wei-ya Ma;Angela Goranson;Zigang Dong

  • Molecular targets of phytochemicals for cancer prevention

    Ki Won Lee;Ann M. Bode;Zigang Dong

  • Inhibition of Tumor Promoter-induced Activator Protein 1 Activation and Cell Transformation by Tea Polyphenols, (-)-Epigallocatechin Gallate, and Theaflavins

    Zigang Dong;Wei Ya Ma;Chuanshu Huang;Chung S. Yang

  • Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.

    Zigang Dong;Michael J. Birrer;Rebecca G. Watts;Lynn M. Matrisian

  • ERKs and p38 Kinase Phosphorylate p53 Protein at Serine 15 in Response to UV Radiation

    Qing Bai She;Nanyue Chen;Zigang Dong

  • Cell Apoptosis: Requirement of H2AX in DNA Ladder Formation, but Not for the Activation of Caspase-3

    Chengrong Lu;Feng Zhu;Yong Yeon Cho;Faqing Tang

  • The functional contrariety of JNK.

    Ann M. Bode;Zigang Dong

  • Inhibition of Activator Protein 1 Activity and Cell Growth by Purified Green Tea and Black Tea Polyphenols in H-ras-transformed Cells Structure-Activity Relationship and Mechanisms Involved

    Jee Y. Chung;Chuanshu Huang;Xiaofeng Meng;Zigang Dong

  • Implications of Genetic and Epigenetic Alterations of CDKN2A (p16INK4a) in Cancer

    Ran Zhao;Bu Young Choi;Mee Hyun Lee;Ann M. Bode

  • Mitogen-activated protein kinase activation in UV-induced signal transduction.

    Ann M. Bode;Zigang Dong

  • Targeting AURKA in Cancer: molecular mechanisms and opportunities for Cancer therapy

    Ruijuan Du;Chuntian Huang;Kangdong Liu;Xiang Li

  • p38 Kinase Mediates UV-induced Phosphorylation of p53 Protein at Serine 389

    Chuanshu Huang;Wei Ya Ma;Aaron Maxiner;Yi Sun

  • Molecular mechanism of the chemopreventive effect of resveratrol.

    Zigang Dong

  • (-)-Epigallocatechin gallate overcomes resistance to etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78.

    Svetlana P. Ermakova;Bong Seok Kang;Bu Young Choi;Hong Seok Choi

  • Aspirin Inhibits Serine Phosphorylation of Insulin Receptor Substrate 1 in Tumor Necrosis Factor-treated Cells through Targeting Multiple Serine Kinases

    Zhanguo Gao;Aamir Zuberi;Michael J. Quon;Zigang Dong

  • The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effects

    Ann M. Bode;Zigang Dong

  • Suppression of Skin Tumorigenesis in c-Jun NH2-Terminal Kinase-2-Deficient Mice

    Nanyue Chen;Masaaki Nomura;Qing Bai She;Wei-Ya Ma

Frequent Co-Authors

Ann M. Bode
Ann M. Bode University of Minnesota
Wei-Ya Ma
Wei-Ya Ma University of Minnesota
Feng Zhu
Feng Zhu Zhejiang University
Ki Won Lee
Ki Won Lee Seoul National University
Chuanshu Huang
Chuanshu Huang New York University
Hyong Joo Lee
Hyong Joo Lee Seoul National University
Ya Cao
Ya Cao Central South University
G. Tim Bowden
G. Tim Bowden University of Arizona
Ronald A. Lubet
Ronald A. Lubet National Institutes of Health
David S. Alberts
David S. Alberts University of Arizona

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