D-Index & Metrics Best Publications
Medicine
Singapore
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 126 Citations 44,168 437 World Ranking 1691 National Ranking 2

Research.com Recognitions

Awards & Achievements

2023 - Research.com Medicine in Singapore Leader Award

2022 - Research.com Medicine in Singapore Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Enzyme

His scientific interests lie mostly in Cancer research, Cancer, Pharmacology, Transcription factor and Angiogenesis. The various areas that Gautam Sethi examines in his Cancer research study include Cell growth, Apoptosis, STAT3, Signal transduction and Kinase. His Cancer research includes elements of Chemokine, NF-κB and Immunology.

His Pharmacology research is multidisciplinary, relying on both Caspase, Cancer prevention, Drug discovery and Arthritis. Gautam Sethi usually deals with Transcription factor and limits it to topics linked to Carcinogenesis and Intracellular. His Angiogenesis study incorporates themes from Gemcitabine and Honokiol.

His most cited work include:

  • Inflammation and cancer: How hot is the link? (1056 citations)
  • The Vascular Endothelium and Human Diseases (593 citations)
  • Curcumin: Getting Back to the Roots (510 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Cancer research, Cancer, Apoptosis, Kinase and Pharmacology. His Cancer research study deals with STAT3 intersecting with Protein tyrosine phosphatase. His Cancer study combines topics in areas such as Inflammation and Immunology.

His Apoptosis research is multidisciplinary, incorporating elements of Molecular biology, Downregulation and upregulation, Cell growth and Cell biology. His studies in Kinase integrate themes in fields like Cell cycle, IκBα and Death domain. His work is dedicated to discovering how Pharmacology, In vivo are connected with In vitro and other disciplines.

He most often published in these fields:

  • Cancer research (66.32%)
  • Cancer (42.15%)
  • Apoptosis (28.72%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cancer research (66.32%)
  • Cancer (42.15%)
  • Carcinogenesis (15.70%)

In recent papers he was focusing on the following fields of study:

Gautam Sethi mostly deals with Cancer research, Cancer, Carcinogenesis, Apoptosis and Metastasis. The study incorporates disciplines such as STAT3, Protein kinase B, Signal transduction, Cancer cell and Kinase in addition to Cancer research. His research on Protein kinase B also deals with topics like

  • PI3K/AKT/mTOR pathway that connect with fields like Mesenchymal stem cell,
  • Angiogenesis, which have a strong connection to Tumor microenvironment.

Gautam Sethi has researched Cancer in several fields, including Inflammation, Drug and Bioinformatics. Within one scientific family, Gautam Sethi focuses on topics pertaining to Transcription factor under Carcinogenesis, and may sometimes address concerns connected to Cell and microRNA. Gautam Sethi works mostly in the field of Apoptosis, limiting it down to concerns involving Cell growth and, occasionally, Casticin.

Between 2018 and 2021, his most popular works were:

  • Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements (145 citations)
  • The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges. (137 citations)
  • Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication. (86 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Enzyme

His primary areas of investigation include Cancer research, Cancer, Carcinogenesis, Metastasis and Signal transduction. His research integrates issues of Cancer cell, STAT3, Transcription factor and Protein kinase B in his study of Cancer research. Gautam Sethi has included themes like Stat3 Signaling Pathway, Cell, Downregulation and upregulation and Kinase in his Transcription factor study.

His work carried out in the field of Cancer brings together such families of science as Inflammation, Oncology and Cell biology. His work investigates the relationship between Carcinogenesis and topics such as Epithelial–mesenchymal transition that intersect with problems in Transdifferentiation. His biological study deals with issues like Epigenetics, which deal with fields such as Cancer stem cell, RNA and Gene expression.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Inflammation and cancer: How hot is the link?

Bharat B. Aggarwal;Shishir Shishodia;Santosh K. Sandur;Manoj K. Pandey.
Biochemical Pharmacology (2006)

1655 Citations

The Vascular Endothelium and Human Diseases

Peramaiyan Rajendran;Thamaraiselvan Rengarajan;Jayakumar Thangavel;Yutaka Nishigaki.
International Journal of Biological Sciences (2013)

1347 Citations

Curcumin: Getting Back to the Roots

Shishir Shishodia;Gautam Sethi;Bharat B. Aggarwal.
Annals of the New York Academy of Sciences (2005)

842 Citations

Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism

Santosh K. Sandur;Manoj K. Pandey;Bokyung Sung;Kwang Seok Ahn.
Carcinogenesis (2007)

715 Citations

Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.

Kodappully Sivaraman Siveen;Sakshi Sikka;Rohit Surana;Xiaoyun Dai.
Biochimica et Biophysica Acta (2014)

653 Citations

Targeting Signal‐Transducer‐and‐Activator‐of‐Transcription‐3 for Prevention and Therapy of Cancer

Bharat B. Aggarwal;Gautam Sethi;Kwang Seok Ahn;Santosh K. Sandur.
Annals of the New York Academy of Sciences (2006)

585 Citations

Nuclear Factor-κB Activation: From Bench to Bedside:

Gautam Sethi;Bokyung Sung;Bharat B. Aggarwal.
Experimental Biology and Medicine (2008)

582 Citations

Thymoquinone: Potential cure for inflammatory disorders and cancer

Chern Chiuh Woo;Alan Prem Kumar;Alan Prem Kumar;Gautam Sethi;Kwong Huat Benny Tan.
Biochemical Pharmacology (2012)

554 Citations

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-κB–regulated antiapoptotic and cell survival gene products in human multiple myeloma cells

Anjana Bhardwaj;Gautam Sethi;Saroj Vadhan-Raj;Carlos Bueso-Ramos.
Blood (2007)

516 Citations

TNF: a master switch for inflammation to cancer.

Gautam Sethi;Bokyung Sung;Bharat B Aggarwal.
Frontiers in Bioscience (2008)

497 Citations

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