World's Best Scientists 2026 revealed!
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Medicine
Singapore
2026

D-Index & Metrics

Medicine

D-Index
150
Citations
67415
World Ranking
1169
National Ranking
4

Research.com Recognitions

  • 2026 - Research.com Medicine in Singapore Leader Award
  • 2025 - Research.com Medicine in Singapore Leader Award
  • 2023 - Research.com Medicine in Singapore Leader Award
  • 2022 - Research.com Medicine in Singapore Leader Award

Overview

Gautam Sethi is affiliated with the National University of Singapore in Singapore. Their research spans multiple domains primarily within biochemistry, genetics, molecular biology, and medicine.

The scientist's work is notably concentrated in several subfields, including:

  • Molecular Biology
  • Oncology
  • Cancer Research
  • Pharmacology
  • Organic Chemistry

Their main research topics focus on areas such as:

  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Autophagy in Disease and Therapy
  • Cancer Cells and Metastasis
  • Extracellular vesicles in disease
  • Cytokine Signaling Pathways and Interactions

Recent papers authored or co-authored by Gautam Sethi include:

  • PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer, 2023, Molecular Cancer
  • Emerging role of exosomes in cancer progression and tumor microenvironment remodeling, 2022, Journal of Hematology & Oncology
  • The multifaceted role of reactive oxygen species in tumorigenesis, 2020, Cellular and Molecular Life Sciences
  • Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review, 2020, Molecules
  • Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy, 2024, Journal of Hematology & Oncology

The researcher frequently publishes in several specialized venues, which include:

  • Pharmacological Research
  • Cancer Letters
  • Life Sciences
  • Cancers
  • Seminars in Cancer Biology

Collaboration is a significant aspect of their work, with frequent co-authors being:

  • Kwang Seok Ahn
  • Ajaikumar B. Kunnumakkara
  • Alan Prem Kumar
  • Milad Ashrafizadeh
  • Chakrabhavi Dhananjaya Mohan

Gautam Sethi has also contributed to academic literature through books published by World Scientific. Titles include:

  • Non-coding RNA Transcripts in Cancer Therapy (2022)
  • An Introduction to Principles and Practice of Respiratory Medicine (2022)
  • Liver Cancer and Phytomedicine (2024)

Best Publications

  • Inflammation and cancer: How hot is the link?

    Bharat B. Aggarwal;Shishir Shishodia;Santosh K. Sandur;Manoj K. Pandey

  • The Vascular Endothelium and Human Diseases

    Peramaiyan Rajendran;Thamaraiselvan Rengarajan;Jayakumar Thangavel;Yutaka Nishigaki

  • The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges.

    Chin-Yap Loh;Jian Yi Chai;Ting Fang Tang;Won Fen Wong

  • Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements.

    Vaishali Aggarwal;Hardeep Singh Tuli;Ayşegül Varol;Falak Thakral

  • Curcumin: Getting Back to the Roots

    Shishir Shishodia;Gautam Sethi;Bharat B. Aggarwal

  • Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism

    Santosh K. Sandur;Manoj K. Pandey;Bokyung Sung;Kwang Seok Ahn

  • Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.

    Kodappully Sivaraman Siveen;Sakshi Sikka;Rohit Surana;Xiaoyun Dai

  • The Role of Resveratrol in Cancer Therapy

    Jeong-Hyeon Ko;Gautam Sethi;Jae-Young Um;Muthu K Shanmugam

  • Thymoquinone: Potential cure for inflammatory disorders and cancer

    Chern Chiuh Woo;Alan Prem Kumar;Alan Prem Kumar;Gautam Sethi;Kwong Huat Benny Tan

  • Targeting Signal‐Transducer‐and‐Activator‐of‐Transcription‐3 for Prevention and Therapy of Cancer

    Bharat B. Aggarwal;Gautam Sethi;Kwang Seok Ahn;Santosh K. Sandur

  • Nuclear Factor-κB Activation: From Bench to Bedside:

    Gautam Sethi;Bokyung Sung;Bharat B. Aggarwal

  • TNF: a master switch for inflammation to cancer.

    Gautam Sethi;Bokyung Sung;Bharat B Aggarwal

  • The Multifaceted Role of Curcumin in Cancer Prevention and Treatment

    Muthu K. Shanmugam;Grishma Rane;Madhu Mathi Kanchi;Frank Arfuso

  • Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-κB–regulated antiapoptotic and cell survival gene products in human multiple myeloma cells

    Anjana Bhardwaj;Gautam Sethi;Saroj Vadhan-Raj;Carlos Bueso-Ramos

  • Targeting transcription factor NF-kappaB to overcome chemoresistance and radioresistance in cancer therapy.

    Feng Li;Gautam Sethi

  • Natural products as a gold mine for arthritis treatment

    Dinesh Khanna;Gautam Sethi;Kwang Seok Ahn;Manoj K Pandey

  • Dual role of autophagy in hallmarks of cancer.

    Shikha Satendra Singh;Somya Vats;Amelia Yi-Qian Chia;Tuan Zea Tan

  • Exosome-Mediated Metastasis: From Epithelial-Mesenchymal Transition to Escape from Immunosurveillance

    Nicholas Syn;Lingzhi Wang;Gautam Sethi;Jean-Paul Thiery

  • Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Suppresses NF-κB Activation and NF-κB-regulated Gene Products Through Modulation of p65 and IκBα Kinase Activation, Leading to Potentiation of Apoptosis Induced by Cytokine and Chemotherapeutic Agents

    Santosh K. Sandur;Haruyo Ichikawa;Gautam Sethi;Kwang Seok Ahn

  • Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-κB–regulated gene products and TAK1-mediated NF-κB activation

    Gautam Sethi;Kwang Seok Ahn;Manoj K. Pandey;Bharat B. Aggarwal

Frequent Co-Authors

Alan Prem Kumar
Alan Prem Kumar National University of Singapore
Kwang Seok Ahn
Kwang Seok Ahn Kyung Hee University
Muthu K. Shanmugam
Muthu K. Shanmugam National University of Singapore
Frank Arfuso
Frank Arfuso University of Western Australia
Feng Li
Feng Li Shandong University
Ajaikumar B. Kunnumakkara
Ajaikumar B. Kunnumakkara Indian Institute of Technology Guwahati
Kam M. Hui
Kam M. Hui National Cancer Centre Singapore
Kanchugarakoppal S. Rangappa
Kanchugarakoppal S. Rangappa University of Mysore
Bokyung Sung
Bokyung Sung The University of Texas Health Science Center at Houston
Anupam Bishayee
Anupam Bishayee Lake Erie College of Osteopathic Medicine

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