Alan Prem Kumar

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Singapore Leader Award
• 2025 - Research.com Biology and Biochemistry in Singapore Leader Award

Overview

Best Publications

• Targeting the STAT3 signaling pathway in cancer: role of synthetic and natural inhibitors.

  Kodappully Sivaraman Siveen;Sakshi Sikka;Rohit Surana;Xiaoyun Dai

  743
  Citations

• The Role of Resveratrol in Cancer Therapy

  Jeong-Hyeon Ko;Gautam Sethi;Jae-Young Um;Muthu K Shanmugam

  655
  Citations

• Thymoquinone: Potential cure for inflammatory disorders and cancer

  Chern Chiuh Woo;Alan Prem Kumar;Alan Prem Kumar;Gautam Sethi;Kwong Huat Benny Tan

  617
  Citations

• The Multifaceted Role of Curcumin in Cancer Prevention and Treatment

  Muthu K. Shanmugam;Grishma Rane;Madhu Mathi Kanchi;Frank Arfuso

  544
  Citations

• Dual role of autophagy in hallmarks of cancer.

  Shikha Satendra Singh;Somya Vats;Amelia Yi-Qian Chia;Tuan Zea Tan

  491
  Citations

• Ageing and the telomere connection: An intimate relationship with inflammation.

  Jingwen Zhang;Grishma Rane;Xiaoyun Dai;Muthu K. Shanmugam

  409
  Citations

• Antioxidant response elements: Discovery, classes, regulation and potential applications.

  Azhwar Raghunath;Kiruthika Sundarraj;Raju Nagarajan;Frank Arfuso

  400
  Citations

• Multifaceted link between cancer and inflammation

  Gautam Sethi;Muthu K. Shanmugam;Lalitha Ramachandran;Alan Prem Kumar

  387
  Citations

• Deformability study of breast cancer cells using microfluidics

  H. W. Hou;Q. S. Li;G. Y. H. Lee;A. P. Kumar

  365
  Citations

• Ursolic acid in cancer prevention and treatment: Molecular targets, pharmacokinetics and clinical studies

  Muthu K. Shanmugam;Xiaoyun Dai;Alan Prem Kumar;Benny K.H. Tan

  341
  Citations

• Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma.

  Aruljothi Subramaniam;Muthu K. Shanmugam;Ekambaram Perumal;Feng Li

  338
  Citations

• Targeting autophagy using natural compounds for cancer prevention and therapy

  Shuo Deng;Muthu K. Shanmugam;Alan Prem Kumar;Celestial T. Yap;Celestial T. Yap

  319
  Citations

• Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer

  Deepti Shrimali;Muthu K. Shanmugam;Alan Prem Kumar;Jingwen Zhang

  284
  Citations

• Oleanolic acid and its synthetic derivatives for the prevention and therapy of cancer: Preclinical and clinical evidence

  Muthu K. Shanmugam;Xiaoyun Dai;Alan Prem Kumar;Benny K.H. Tan

  277
  Citations

• Wnt signaling in triple-negative breast cancer.

  S. Pohl;N. Brook;Mark Agostino;Frank Arfuso

  275
  Citations

• Targeting transcription factor STAT3 for cancer prevention and therapy.

  Edna Zhi Pei Chai;Muthu K. Shanmugam;Frank Arfuso;Arunasalam Dharmarajan

  272
  Citations

• Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathway

  Chern Chiuh Woo;Ser Yue Loo;Veronica Gee;Chun Wei Yap

  266
  Citations

• Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: potential role in prevention and therapy of cancer.

  Muthu K. Shanmugam;An H. Nguyen;Alan Prem Kumar;Alan Prem Kumar;Benny K-H Tan

  257
  Citations

• Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS

  Chern Chiuh Woo;Annie Hsu;Alan Prem Kumar;Gautam Sethi

  231
  Citations

• Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds

  Muthu K Shanmugam;Jong Hyun Lee;Edna Zhi Pei Chai;Madhu Mathi Kanchi

  224
  Citations