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Biology and Biochemistry

D-Index
81
Citations
21339
World Ranking
3935
National Ranking
1942

Overview

Carole R. Mendelson is affiliated with The University of Texas Southwestern Medical Center in the United States. Their research primarily falls within the field of Medicine, focusing on several specialized subfields including Pulmonary and Respiratory Medicine, Surgery, Immunology, Molecular Biology, and Oncology.

The scientist's recent work addresses complex biological and medical issues, encompassing topics such as Neonatal Respiratory Health Research, Congenital Diaphragmatic Hernia Studies, Reproductive System and Pregnancy, Cancer Immunotherapy and Biomarkers, Estrogen and related hormone effects, Pregnancy and preeclampsia studies, and Epigenetics and DNA Methylation.

Notable recent publications include:

  • Decreased 11β-hydroxysteroid dehydrogenase 1 in lungs of steroid receptor coactivator (Src) -1/-2 double-deficient fetal mice is caused by impaired glucocorticoid and cytokine signaling, 2020, The FASEB Journal
  • NRF2 Serves a Critical Role in Regulation of Immune Checkpoint Proteins (ICPs) During Trophoblast Differentiation, 2022, Endocrinology
  • Role of NRF2 in immune modulator expression in developing lung, 2021, The FASEB Journal
  • IL-1β mediates the induction of immune checkpoint regulators IDO1 and PD-L1 in lung adenocarcinoma cells, 2023, Cell Communication and Signaling
  • Arginase 1 and L-arginine coordinate fetal lung development and the initiation of labor in mice, 2023, EMBO Reports

Frequent co-authors in Mendelson's research collaborations include:

  • Ritu Mishra
  • Afshan F. Nawas
  • Jingfei Chen
  • Lu Gao
  • Yaqin Yu

Mendelson publishes regularly in several journals, with multiple articles appearing in:

  • Journal of the Endocrine Society
  • The FASEB Journal
  • Cell Communication and Signaling
  • Endocrinology
  • EMBO Reports

Best Publications

  • Aromatase Cytochrome P450, The Enzyme Responsible for Estrogen Biosynthesis*

    Evan R. Simpson;Mala S. Mahendroo;Gary D. Means;Michael W. Kilgore

  • Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene.

    Ying Zhao;Veena R. Agarwal;Carole R. Mendelson;Evan R. Simpson

  • Aromatization of androstenedione by human adipose tissue stromal cells in monolayer culture

    Gary E. Ackerman;Margaret E. Smith;Carole R. Mendelson;Paul C. Macdonald

  • Molecular and cellular processing of lung surfactant.

    Seamus A. Rooney;Stephen L. Young;Carole R. Mendelson

  • Aromatase expression in health and disease

    Evan R. Simpson;Ying Zhao;Veena R. Agarwal;M. Dodson Michael

  • Tissue-specific and hormonally controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue.

    Mala S. Mahendroo;Carole R. Mendelson;Evan R. Simpson;Evan R. Simpson

  • Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in nonsteroidogenic cells

    C. J. Corbin;S. Graham-Lorence;M. McPhaul;J. I. Mason

  • Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition

    Jennifer C. Condon;Pancharatnam Jeyasuria;Julie M. Faust;Carole R. Mendelson

  • Up-regulation of the progesterone receptor (PR)-C isoform in laboring myometrium by activation of nuclear factor-κB may contribute to the onset of labor through inhibition of PR function

    Jennifer C. Condon;Daniel B. Hardy;Kelly Kovaric;Carole R. Mendelson

  • A decline in the levels of progesterone receptor coactivators in the pregnant uterus at term may antagonize progesterone receptor function and contribute to the initiation of parturition

    Jennifer C. Condon;Pancharatnam Jeyasuria;Julie M. Faust;James W. Wilson

  • Minireview: fetal-maternal hormonal signaling in pregnancy and labor.

    Carole R. Mendelson

  • Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis.

    G. D. Means;Mala Mahendroo;C. J. Corbin;J. M. Mathis;J. M. Mathis

  • Tissue-Specific Promoters Regulate Aromatase Cytochrome P450 Gene Expression in Human Ovary and Fetal Tissues

    Gary D. Means;Michael W. Kilgore;Mala S. Mahendroo;Carole R. Mendelson

  • miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor

    Nora E. Renthal;Chien Cheng Chen;Koriand'R C. Williams;Robert D. Gerard

  • Aromatase P450 gene expression in human adipose tissue. Role of a Jak/STAT pathway in regulation of the adipose-specific promoter.

    Ying Zhao;John E. Nichols;Serdar E. Bulun;Carole R. Mendelson

  • Progesterone Receptor Plays a Major Antiinflammatory Role in Human Myometrial Cells by Antagonism of Nuclear Factor-κB Activation of Cyclooxygenase 2 Expression

    Daniel B. Hardy;Bethany A. Janowski;David R. Corey;Carole R. Mendelson

  • Effects of aging and obesity on aromatase activity of human adipose cells

    William H. Cleland;Carole R. Mendelson;Evan R. Simpson

  • Mechanisms in tissue-specific regulation of estrogen biosynthesis in humans

    Amrita Kamat;Margaret M Hinshelwood;Barbara A Murry;Carole R Mendelson

  • Role of Transcription Factors in Fetal Lung Development and Surfactant Protein Gene Expression

    Carole R. Mendelson

  • Immunolocalization of aromatase, 17α-hydroxylase and side-chain-cleavage cytochromes P-450 in the human ovary

    H. Sasano;M. Okamoto;J. I. Mason;E. R. Simpson

Frequent Co-Authors

Evan R. Simpson
Evan R. Simpson Hudson Institute of Medical Research
John M. Johnston
John M. Johnston The University of Texas Southwestern Medical Center
Serdar E. Bulun
Serdar E. Bulun Northwestern University
Paul C. MacDonald
Paul C. MacDonald The University of Texas Southwestern Medical Center
Bruce R. Carr
Bruce R. Carr The University of Texas Southwestern Medical Center
John M. Shelton
John M. Shelton The University of Texas Southwestern Medical Center
James A. Richardson
James A. Richardson The University of Texas Southwestern Medical Center
Robert D. Gerard
Robert D. Gerard The University of Texas Southwestern Medical Center
Michael R. Waterman
Michael R. Waterman Vanderbilt University
David R. Corey
David R. Corey The University of Texas Southwestern Medical Center

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