D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 88 Citations 25,236 270 World Ranking 1221 National Ranking 734

Research.com Recognitions

Awards & Achievements

2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Michael R. Waterman mainly investigates Biochemistry, Molecular biology, Cytochrome P450, Internal medicine and Gene. His Molecular biology study combines topics from a wide range of disciplines, such as Reductase, Transcription, Regulatory sequence, Peptide sequence and Reporter gene. His research in Cytochrome P450 intersects with topics in Chromosome, Computational biology, Site-directed mutagenesis and Function.

His research integrates issues of Endocrinology, Lyase and 20-Hydroxyeicosatetraenoic acid in his study of Internal medicine. His Gene study necessitates a more in-depth grasp of Genetics. In the subject of general Genetics, his work in Gene family and Pseudogene is often linked to Arabic numerals, thereby combining diverse domains of study.

His most cited work include:

  • P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature (2562 citations)
  • The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature. (958 citations)
  • The P450 gene superfamily: recommended nomenclature. (694 citations)

What are the main themes of his work throughout his whole career to date?

Michael R. Waterman mainly focuses on Biochemistry, Molecular biology, Internal medicine, Endocrinology and Cytochrome P450. His Biochemistry study focuses mostly on Enzyme, Cytochrome, Sterol, Amino acid and Escherichia coli. His work focuses on many connections between Sterol and other disciplines, such as Trypanosoma brucei, that overlap with his field of interest in Stereochemistry.

His work carried out in the field of Molecular biology brings together such families of science as Gene expression, Complementary DNA, Reporter gene, Gene and Transcription. His study with Gene involves better knowledge in Genetics. Michael R. Waterman works mostly in the field of Cytochrome P450, limiting it down to concerns involving Reductase and, occasionally, Cytochrome P450 reductase.

He most often published in these fields:

  • Biochemistry (44.27%)
  • Molecular biology (29.72%)
  • Internal medicine (21.05%)

What were the highlights of his more recent work (between 2005-2021)?

  • Biochemistry (44.27%)
  • Sterol (10.84%)
  • Trypanosoma brucei (4.95%)

In recent papers he was focusing on the following fields of study:

Michael R. Waterman focuses on Biochemistry, Sterol, Trypanosoma brucei, Stereochemistry and Enzyme. His Biochemistry study frequently draws connections between related disciplines such as Pharmacology. The Sterol study combines topics in areas such as Gene and Ergosterol.

In Gene, Michael R. Waterman works on issues like Crustacean, which are connected to Internal medicine and Endocrinology. His Stereochemistry research incorporates themes from Oxidoreductase, Substrate, Binding site and Active site. His Enzyme research is multidisciplinary, incorporating elements of Steroid, Steroid 21-Hydroxylase and Fusion protein.

Between 2005 and 2021, his most popular works were:

  • Sterol 14α-Demethylase Cytochrome P450 (CYP51), a P450 in all Biological Kingdoms (260 citations)
  • Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel (123 citations)
  • Structural Insights into Inhibition of Sterol 14α-Demethylase in the Human Pathogen Trypanosoma cruzi (112 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

The scientist’s investigation covers issues in Biochemistry, Sterol, Sterol 14-Demethylase, 14-alpha Demethylase Inhibitors and Trypanosoma brucei. Michael R. Waterman interconnects Drug development and Stereochemistry in the investigation of issues within Biochemistry. His 14-alpha Demethylase Inhibitors study integrates concerns from other disciplines, such as Antifungal drug, Drug resistance, Microbiology and Trypanosoma.

His Trypanosoma brucei study also includes fields such as

  • Leishmania infantum which intersects with area such as Virology, Lanosterol and Chagas disease,
  • Enzyme activator which connect with Substrate and Substrate analog. His study in Cytochrome P450 is interdisciplinary in nature, drawing from both Peptide sequence, Sequence alignment and Function. His Peptide sequence research is within the category of Gene.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature

David R. Nelson;Luc Koymans;Tetsuya Kamataki;John J. Stegeman.
Pharmacogenetics (1996)

3586 Citations

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature.

D W Nebert;D R Nelson;M J Coon;R W Estabrook.
DNA and Cell Biology (1991)

1392 Citations

The P450 gene superfamily: recommended nomenclature.

Nebert Dw;Adesnik M;Coon Mj;Estabrook Rw.
DNA (Mary Ann Liebert, Inc.) (1987)

1012 Citations

The P450 Superfamily: Updated Listing of All Genes and Recommended Nomenclature for the Chromosomal Loci

Daniel W. Nebert;David R. Nelson;Milton Adesnik;Minor J. Coon.
DNA (Mary Ann Liebert, Inc.) (1989)

816 Citations

Expression and enzymatic activity of recombinant cytochrome P450 17 alpha-hydroxylase in Escherichia coli.

Henry J. Barnes;Michael P. Arlotto;Michael R. Waterman.
Proceedings of the National Academy of Sciences of the United States of America (1991)

749 Citations

Regulation of the Synthesis of Steroidogenic Enzymes in Adrenal Cortical Cells by ACTH

Evan R. Simpson;Michael R. Waterman.
Annual Review of Physiology (1988)

682 Citations

Crystal structure of cytochrome P450 14α-sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors

Larissa M. Podust;Thomas L. Poulos;Michael R. Waterman.
Proceedings of the National Academy of Sciences of the United States of America (2001)

650 Citations

Expression of bovine 17 alpha-hydroxylase cytochrome P-450 cDNA in nonsteroidogenic (COS 1) cells

Mauricio X. Zuber;Evan R. Simpson;Michael R. Waterman.
Science (1986)

563 Citations

Neurosteroids: cytochrome P-450scc in rat brain

C Le Goascogne;P Robel;M Gouezou;N Sananes.
Science (1987)

505 Citations

17α-Hydroxylase/17,20-Lyase Deficiency: From Clinical Investigation to Molecular Definition*

Toshihiko Yanase;Evan R. Simpson;Michael R. Waterman.
Endocrine Reviews (1991)

464 Citations

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