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Chemistry

D-Index
43
Citations
6713
World Ranking
17238
National Ranking
4232

Overview

W. David Nes is affiliated with Texas Tech University in the United States. Their research spans multiple fields, primarily focusing on medicine and biochemistry, genetics, and molecular biology. Within these broad areas, their work delves into subfields such as surgery, pulmonary and respiratory medicine, nutrition and dietetics, molecular biology, and public health, environmental, and occupational health.

The scientist's main research topics include neonatal respiratory health research, infant nutrition and health, plant biochemistry and biosynthesis, cholesterol and lipid metabolism, cancer, lipids, and metabolism, intestinal malrotation and obstruction disorders, as well as clinical nutrition and gastroenterology.

W. David Nes has published articles in a variety of scientific venues. Frequent publication venues include:

  • Journal of Pediatric Surgery
  • Journal of Perinatology
  • Journal of Pediatric Gastroenterology and Nutrition
  • bioRxiv (Cold Spring Harbor Laboratory)
  • New Phytologist

Some of the recent papers involving W. David Nes or related research are:

  • "Pollen sterols are associated with phylogeny and environment but not with pollinator guilds," 2021, New Phytologist
  • "Building Communication and Conflict Management Awareness in Surgical Education," 2021, Journal of Surgical Education
  • "Unearthing the Janus-face cholesterogenesis pathways in cancer," 2021, Biochemical Pharmacology
  • "Association between neurodevelopmental outcomes and concomitant presence of NEC and IVH in extremely low birth weight infants," 2023, Journal of Perinatology
  • "Factors Associated With Chronic Intestinal Inflammation Resembling Inflammatory Bowel Disease in Pediatric Intestinal Failure," 2023, Journal of Pediatric Gastroenterology and Nutrition

W. David Nes collaborates frequently with several coauthors, including:

  • Tom Jaksic
  • Biren P. Modi
  • Katherine Culbreath
  • G.P. Keefe
  • Erika M. Edwards

Best Publications

  • Biosynthesis of cholesterol and other sterols.

    W. David Nes

  • STEROL METHYLTRANSFERASE 1 Controls the Level of Cholesterol in Plants

    Andrew C. Diener;Haoxia Li;Wen-xu Zhou;Wendy J. Whoriskey

  • Identification of Natural RORγ Ligands that Regulate the Development of Lymphoid Cells

    Fabio R. Santori;Pengxiang Huang;Serge A. van de Pavert;Eugene F. Douglass

  • The Metabolism, Structure, and Function of Plant Lipids

    P. K. Stumpf;J. Brian Mudd

  • Sterol 14α-demethylase as a potential target for antitrypanosomal therapy: enzyme inhibition and parasite cell growth

    Galina I. Lepesheva;Robert D. Ott;Tatiana Y. Hargrove;Yuliya Y. Kleshchenko

  • CYP51 from Trypanosoma cruzi A PHYLA-SPECIFIC RESIDUE IN THE B′ HELIX DEFINES SUBSTRATE PREFERENCES OF STEROL 14α-DEMETHYLASE

    Galina I. Lepesheva;Natalia G. Zaitseva;W. David Nes;Wenxu Zhou

  • Carbon-13 nmr studies on sitosterol biosynthesized from [13C]mevalonates

    W.David Nes;Robert A. Norton;Mabry Benson

  • Substrate Preferences and Catalytic Parameters Determined by Structural Characteristics of Sterol 14α-Demethylase (CYP51) from Leishmania infantum

    Tatiana Y. Hargrove;Zdzislaw Wawrzak;Jialin Liu;W. David Nes

  • Analysis of Sterols and Other Biologically Significant Steroids

    W. David Nes;Edward J. Parish

  • Crystal Structures of Trypanosoma brucei Sterol 14α-Demethylase and Implications for Selective Treatment of Human Infections

    Galina I. Lepesheva;Hee Won Park;Tatiana Y. Hargrove;Benoit Vanhollebeke

  • Azole Binding Properties of Candida albicans Sterol 14-α Demethylase (CaCYP51)

    Andrew G. S. Warrilow;Claire M. Martel;Josie E. Parker;Nadja Melo

  • CYP51 : A Major Drug Target in the Cytochrome P450 Superfamily

    Galina I. Lepesheva;Tatyana Y. Hargrove;Yuliya Kleshchenko;W. David Nes

  • Identification of the lipophilic factor produced by macrophages that stimulates steroidogenesis.

    W. David Nes;Yevgeniya O. Lukyanenko;Zhong Hua Jia;Stéphane Quideau

  • Expression, Purification, and Characterization of Aspergillus fumigatus Sterol 14-α Demethylase (CYP51) Isoenzymes A and B

    Andrew G. S. Warrilow;Nadja Melo;Claire M. Martel;Josie E. Parker

  • CYP51 from Trypanosoma brucei is obtusifoliol-specific.

    Galina I Lepesheva;W David Nes;Wenxu Zhou;George C Hill

  • A Comparison of Triterpenoids with Steroids as Membrane Components

    W. David Nes;Erich Heftmann

  • Mechanism of Binding of Prothioconazole to Mycosphaerella graminicola CYP51 Differs from That of Other Azole Antifungals

    Josie E. Parker;Andrew G. S. Warrilow;Hans J. Cools;Claire M. Martel

  • Mechanism and structural requirements for transformation of substrates by the (S)-adenosyl-L-methionine:delta 24(25)-sterol methyl transferase from Saccharomyces cerevisiae.

    Mylavarapu Venkatramesh;De An Guo;Zhonghua Jia;W. David Nes

  • Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Δ7-24, 25-dihydrolanosterol

    Tatiana Y. Hargrove;Zdzislaw Wawrzak;Jialin Liu;Michael R. Waterman

  • Biosynthesis of phytosterols: Kinetic mechanism for the enzymatic C-methylation of sterols

    W.David Nes;Zhihong Song;Allen L. Dennis;Wenxu Zhou

Frequent Co-Authors

Steven L. Kelly
Steven L. Kelly Swansea University
Diane E. Kelly
Diane E. Kelly Swansea University
Michael R. Waterman
Michael R. Waterman Vanderbilt University
Philip C. Stevenson
Philip C. Stevenson Royal Botanic Gardens
Henry T. Nguyen
Henry T. Nguyen University of Missouri
F. Peter Guengerich
F. Peter Guengerich Vanderbilt University
David M. Virshup
David M. Virshup Duke NUS Graduate Medical School
Craig W. Lindsley
Craig W. Lindsley Vanderbilt University
Robert A. Moreau
Robert A. Moreau United States Department of Agriculture

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