David M. Virshup

Research.com Recognitions

• 2026 - Research.com Biology and Biochemistry in Singapore Leader Award
• 2023 - Research.com Biology and Biochemistry in Singapore Leader Award
• 2022 - Research.com Biology and Biochemistry in Singapore Leader Award
• 2013 - Fellow of the American Association for the Advancement of Science (AAAS)
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• An hPer2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome

  Kong L. Toh;Christopher R. Jones;Yan He;Erik J. Eide

  1772
  Citations

• Post-translational modifications regulate the ticking of the circadian clock

  Monica Gallego;David M. Virshup

  982
  Citations

• From Promiscuity to Precision: Protein Phosphatases Get a Makeover

  David M. Virshup;Shirish Shenolikar

  726
  Citations

• Control of Mammalian Circadian Rhythm by CKIε-Regulated Proteasome-Mediated PER2 Degradation

  Erik J. Eide;Margaret F. Woolf;Heeseog Kang;Peter Woolf

  593
  Citations

• Regulation of β-Catenin Signaling by the B56 Subunit of Protein Phosphatase 2A

  Joni M. Seeling;Jeffrey R. Miller;Rosario Gil;Randall T. Moon

  586
  Citations

• The B56 Family of Protein Phosphatase 2A (PP2A) Regulatory Subunits Encodes Differentiation-induced Phosphoproteins That Target PP2A to Both Nucleus and Cytoplasm

  Brent McCright;Ann M. Rivers;Scott Audlin;David M. Virshup

  485
  Citations

• Nuclear Entry of the Circadian Regulator mPER1 Is Controlled by Mammalian Casein Kinase I ɛ

  Erica Vielhaber;Erik Eide;Ann Rivers;Zhong Hua Gao

  428
  Citations

• Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins.

  Qing Jun Meng;Larisa Logunova;Elizabeth S. Maywood;Monica Gallego

  425
  Citations

• Protein phosphatase 2A: a panoply of enzymes.

  David M Virshup

  425
  Citations

• The Circadian Regulatory Proteins BMAL1 and Cryptochromes Are Substrates of Casein Kinase Iε

  Erik J. Eide;Erica L. Vielhaber;William A. Hinz;David M. Virshup

  422
  Citations

• Pharmacological Inhibition of the Wnt Acyltransferase PORCN Prevents Growth of WNT-Driven Mammary Cancer

  Kyle David Proffitt;Babita Madan;Zhiyuan Ke;Vishal Pendharkar

  395
  Citations

• Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts

  Zahra Kabiri;Gediminas Greicius;Babita Madan;Steffen Biechele

  331
  Citations

• Wnt addiction of genetically defined cancers reversed by PORCN inhibition

  B Madan;Z Ke;N Harmston;S Y Ho

  327
  Citations

• Identification of cellular proteins required for simian virus 40 DNA replication.

  M S Wold;D H Weinberg;D M Virshup;J J Li

  311
  Citations

• Casein kinase I phosphorylates and destabilizes the β-catenin degradation complex

  Zhong Hua Gao;Joni M. Seeling;Virginia Hill;April Yochum

  306
  Citations

• Identification of a new family of protein phosphatase 2A regulatory subunits.

  Brent McCright;David M. Virshup

  286
  Citations

• Casein kinase 1: Complexity in the family.

  Jit Kong Cheong;David M. Virshup

  276
  Citations

• A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1.

  Heidi Okamura;Carmen Garcia-Rodriguez;Holly Martinson;Jun Qin

  263
  Citations

• PDGFRα+ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo.

  Gediminas Greicius;Zahra Kabiri;Kristmundur Sigmundsson;Chao Liang

  258
  Citations

• Isolation and Characterization of Human Casein Kinase I (CKI), a Novel Member of the CKI Gene Family

  Kimberly J. Fish;Aleksandra Cegielska;Michael E. Getman;Gregory M. Landes

  256
  Citations