David L. Boyle

Overview

Best Publications

• Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry.

  Fan Zhang;Kevin Wei;Kamil Slowikowski;Chamith Y Fonseka

  1397
  Citations

• c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis

  Zuoning Han;David L. Boyle;Lufen Chang;Brydon Bennett

  1012
  Citations

• Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist

  Hal M Hoffman;Hal M Hoffman;Sanna Rosengren;David L Boyle;Jae Y Cho

  638
  Citations

• AP-1 and NF-KB Regulation in Rheumatoid Arthritis and Murine Collagen-Induced Arthritis

  Zuoning Han;D. L. Boyle;A. M. Manning;G. S. Firestein

  509
  Citations

• Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity

  Susannah D. Brydges;Susannah D. Brydges;James L. Mueller;James L. Mueller;Matthew D. McGeough;Carla A. Pena

  350
  Citations

• DNA methylome signature in rheumatoid arthritis

  Kazuhisa Nakano;John W Whitaker;David L Boyle;Wei Wang

  344
  Citations

• Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation.

  Paul P. Tak;Paul P. Tak;Danielle M. Gerlag;Danielle M. Gerlag;Karl R. Aupperle;Deliana A. Van De Geest

  301
  Citations

• The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis

  D L Boyle;K Soma;J Hodge;A Kavanaugh

  280
  Citations

• Regional analysis of p53 mutations in rheumatoid arthritis synovium

  Yuji Yamanishi;David L. Boyle;Sanna Rosengren;Douglas R. Green

  276
  Citations

• Fibroblast-Like Synoviocytes of Mesenchymal Origin Express Functional B Cell-Activating Factor of the TNF Family in Response to Proinflammatory Cytokines

  Junko Ohata;Nathan J. Zvaifler;Mitsufumi Nishio;David L. Boyle

  271
  Citations

• Synovial interleukin-1 receptor antagonist and interleukin-1 balance in rheumatoid arthritis.

  Gary S. Firestein;David L. Boyle;Carolyn Yu;Mary M. Paine

  266
  Citations

• Synovial tissue research: a state-of-the-art review

  Carl Orr;Elsa Sousa;David L Boyle;Maya H Buch

  263
  Citations

• Expression and Regulation of Aggrecanase in Arthritis: The Role of TGF-β

  Yuji Yamanishi;David L. Boyle;Melody Clark;Rich A. Maki

  243
  Citations

• Apoptosis in rheumatoid arthritis: p53 overexpression in rheumatoid arthritis synovium.

  G S Firestein;K Nguyen;K R Aupperle;M Yeo

  223
  Citations

• Adenosine inhibits neutrophil degranulation in activated human whole blood: involvement of adenosine A2 and A3 receptors.

  M. G. Bouma;T. M. M. A. Jeunhomme;D. L. Boyle;M. A. Dentener

  217
  Citations

• Assessment of rituximab’s immunomodulatory synovial effects (ARISE trial). 1: clinical and synovial biomarker results

  Arthur Kavanaugh;Sanna Rosengren;Susan J Lee;Deepa Hammaker

  205
  Citations

• A novel spleen tyrosine kinase inhibitor blocks c-Jun N-terminal kinase-mediated gene expression in synoviocytes

  Hoon-Suk Cha;David L. Boyle;Tomoyuki Inoue;Reineke Schoot

  203
  Citations

• Regulation of Joint Destruction and Inflammation by p53 in Collagen-Induced Arthritis

  Yuji Yamanishi;David L. Boyle;Michael J. Pinkoski;Artin Mahboubi

  201
  Citations

• Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study

  Maya H Buch;David L. Boyle;Sanna Rosengren;Benazir Saleem

  198
  Citations

• Jun N-Terminal Kinase in Rheumatoid Arthritis

  Zuoning Han;David L. Boyle;Karlfried R. Aupperle;Brydon Bennett

  195
  Citations