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Biology and Biochemistry

D-Index
45
Citations
8570
World Ranking
19091
National Ranking
7796

Overview

Paula M. Cannon is affiliated with the University of Southern California in the United States. Their research spans fields primarily within Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to Molecular Biology, Infectious Diseases, Genetics, Oncology, and Epidemiology.

Their work covers several main topics, including:

  • CRISPR and Genetic Engineering
  • Virus-based gene therapy research
  • SARS-CoV-2 and COVID-19 Research
  • CAR-T cell therapy research
  • Viral Infections and Outbreaks Research
  • Cytomegalovirus and herpesvirus research
  • T-cell and B-cell Immunology

Paula M. Cannon has published notably in several scientific venues, with frequent publications appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Therapy
  • Journal of Virology
  • Gene Therapy
  • UNC Libraries

Selected recent papers authored or co-authored by Paula M. Cannon include:

  • Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021, 2021, Nature Medicine
  • Rational Selection of CRISPR-Cas9 Guide RNAs for Homology-Directed Genome Editing, 2020, Molecular Therapy
  • Optimization of AAV6 transduction enhances site-specific genome editing of primary human lymphocytes, 2021, Molecular Therapy - Methods & Clinical Development
  • Cytoplasmic Tail Truncation of SARS-CoV-2 Spike Protein Enhances Titer of Pseudotyped Vectors but Masks the Effect of the D614G Mutation, 2021, Journal of Virology
  • Genome edited B cells: a new frontier in immune cell therapies, 2021, Molecular Therapy

Frequent collaborators in their research include Geoffrey L. Rogers, Hsu-Yu Chen, Chun Huang, George N. Llewellyn, and Hans-Peter Kiem. These co-authors have contributed to multiple joint publications.

Best Publications

  • A transient three-plasmid expression system for the production of high titer retroviral vectors

    Yuko Soneoka;Paula M. Cannon;Emma E. Ramsdale;Joanne C. Griffiths

  • Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

    Nathalia Holt;Jianbin Wang;Kenneth Kim;Geoffrey Friedman

  • International AIDS Society global scientific strategy: towards an HIV cure 2016

    Steven G Deeks;Sharon R Lewin;Anna Laura Ross;Jintanat Ananworanich

  • AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges

    Matthew R. Gardner;Lisa M. Kattenhorn;Hema R. Kondur;Markus von Schaewen

  • Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021.

    Steven G. Deeks;Nancie Archin;Paula Cannon;Simon Collins

  • Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors

    Jianbin Wang;Colin M Exline;Joshua J DeClercq;G Nicholas Llewellyn

  • Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa.

    Mei Chen;Noriyuki Kasahara;Douglas R Keene;Lawrence Chan

  • Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency.

    Marella D Canny;Nathalie Moatti;Leo C K Wan;Leo C K Wan;Amélie Fradet-Turcotte;Amélie Fradet-Turcotte

  • Genomic Editing of the HIV-1 Coreceptor CCR5 in Adult Hematopoietic Stem and Progenitor Cells Using Zinc Finger Nucleases

    Lijing Li;Ludmila Krymskaya;Jianbin Wang;Jill Henley

  • HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment

    Heiko Hauser;Lisa A Lopez;Su Jung Yang;Jill E Oldenburg

  • New World Clade B Arenaviruses Can Use Transferrin Receptor 1 (TfR1)-Dependent and -Independent Entry Pathways, and Glycoproteins from Human Pathogenic Strains Are Associated with the Use of TfR1

    Meg L. Flanagan;Jill Oldenburg;Therese Reignier;Nathalia Holt

  • Sequences in the Cytoplasmic Tail of the Gibbon Ape Leukemia Virus Envelope Protein That Prevent Its Incorporation into Lentivirus Vectors

    Ilias Christodoulopoulos;Paula M. Cannon

  • Human immunodeficiency virus type 1 integrase: effect on viral replication of mutations at highly conserved residues.

    P M Cannon;W Wilson;E Byles;S M Kingsman

  • Ebola virus glycoprotein counteracts BST-2/Tetherin restriction in a sequence-independent manner that does not require tetherin surface removal.

    Lisa A. Lopez;Su Jung Yang;Heiko Hauser;Colin M. Exline

  • Functional analysis of the cytoplasmic tail of Moloney murine leukemia virus envelope protein.

    M M Januszeski;P M Cannon;D Chen;Y Rozenberg

  • Genome editing technologies: defining a path to clinic.

    Jacqueline Corrigan-Curay;Marina O'Reilly;Donald B Kohn;Paula M Cannon

  • Delivery methods and compositions for nuclease-mediated genome engineering

    Paula M. Cannon;Colin Michael Exline;Michael C. Holmes

  • Structure-function studies of the human immunodeficiency virus type 1 matrix protein, p17.

    Paula M. Cannon;Stephen Matthews;Nigel Clark;Elaine D. Byles

  • Chemokine receptor 5 knockout strategies.

    Paula Cannon;Carl June

  • Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells

    David L DiGiusto;Paula M Cannon;Michael C Holmes;Lijing Li

Frequent Co-Authors

Donald B. Kohn
Donald B. Kohn University of California, Los Angeles
Michael C. Holmes
Michael C. Holmes Ambys Medicines
W. French Anderson
W. French Anderson University of Southern California
Philip D. Gregory
Philip D. Gregory Sangamo BioSciences (United States)
Devin Sok
Devin Sok Scripps Research Institute
Ben Murrell
Ben Murrell Karolinska Institute
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Susan M. Kingsman
Susan M. Kingsman Oxford BioMedica (United Kingdom)
Matthew H. Porteus
Matthew H. Porteus Stanford University
Hans Peter Kiem
Hans Peter Kiem Fred Hutchinson Cancer Research Center

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