Susan M. Kingsman

Overview

Best Publications

• A transient three-plasmid expression system for the production of high titer retroviral vectors

  Yuko Soneoka;Paula M. Cannon;Emma E. Ramsdale;Joanne C. Griffiths

  1053
  Citations

• VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

  Mimoun Azzouz;G. Scott Ralph;Erik Storkebaum;Lucy E. Walmsley

  770
  Citations

• Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

  G Scott Ralph;Pippa A Radcliffe;Denise M Day;Janine M Carthy

  637
  Citations

• Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial

  Stéphane Palfi;Jean Marc Gurruchaga;G Scott Ralph;Helene Lepetit

  514
  Citations

• Conservation of high efficiency promoter sequences in Saccharomyces cerevisiae.

  M.J. Dobson;M.F. Tuite;N.A. Roberts;A.J. Kingsman

  443
  Citations

• Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae.

  J. Mellor;M.J. Dobson;N.A. Roberts;M.F. Tuite

  429
  Citations

• Stable gene transfer to the nervous system using a non-primate lentiviral vector

  K A Mitrophanous;S Yoon;J B Rohll;D Patil

  418
  Citations

• A Rev-Independent Human Immunodeficiency Virus Type 1 (HIV-1)-Based Vector That Exploits a Codon-Optimized HIV-1 gag-pol Gene

  Ekaterini Kotsopoulou;V. Narry Kim;Alan J. Kingsman;Alan J. Kingsman;Susan M. Kingsman;Susan M. Kingsman

  393
  Citations

• Minimal Requirement for a Lentivirus Vector Based on Human Immunodeficiency Virus Type 1

  V N Kim;K Mitrophanous;S M Kingsman;S M Kingsman;A J Kingsman;A J Kingsman

  392
  Citations

• HIV expression strategies: Ribosomal frameshifting is directed by a short sequence in both mammalian and yeast systems

  Wilma Wilson;Martin Braddock;Sally E. Adams;Peter D. Rathjen

  299
  Citations

• The macrophage - a novel system to deliver gene therapy to pathological hypoxia.

  L Griffiths;K Binley;S Iqball;O Kan

  298
  Citations

• Multicistronic Lentiviral Vector-Mediated Striatal Gene Transfer of Aromatic l-Amino Acid Decarboxylase, Tyrosine Hydroxylase, and GTP Cyclohydrolase I Induces Sustained Transgene Expression, Dopamine Production, and Functional Improvement in a Rat Model of Parkinson's Disease.

  Mimoun Azzouz;Enca Martin-Rendon;Robert D. Barber;Kyriacos A. Mitrophanous

  291
  Citations

• Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy.

  Mimoun Azzouz;Thanh Le;G. Scott Ralph;Lucy Walmsley

  257
  Citations

• Lentivirus-Mediated Gene Transfer to the Central Nervous System: Therapeutic and Research Applications

  Liang-Fong Wong;Lucy Goodhead;Christine Prat;Kyriacos A. Mitrophanous

  255
  Citations

• The expression of hybrid HIV:Ty virus-like particles in yeast

  Sally E. Adams;Keith M. Dawson;Keith Gull;Susan M. Kingsman

  255
  Citations

• Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: a phase I/II trial.

  Richard Harrop;Noel B Connolly;Irina Redchenko;Juan W Valle

  235
  Citations

• Dopamine Gene Therapy for Parkinson’s Disease in a Nonhuman Primate Without Associated Dyskinesia

  Béchir Jarraya;Sabrina Boulet;G. Scott Ralph;Caroline Jan

  220
  Citations

• A retrovirus-like strategy for expression of a fusion protein encoded by yeast transposon Ty1.

  Jane Mellor;Sandra M. Fulton;Melanie J. Dobson;Wilma Wilson

  219
  Citations

• Regulated high efficiency expression of human interferon-alpha in Saccharomyces cerevisiae.

  M.F. Tuite;M.J. Dobson;N.A. Roberts;R.M. King

  217
  Citations

• Reverse transcriptase activity and Ty RNA are associated with virus-like particles in yeast

  Jane Mellor;Michael H. Malim;Keith Gull;Mick F. Tuite

  209
  Citations