World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
45
Citations
10177
World Ranking
4212
National Ranking
1816

Overview

Philip J. Farabaugh is affiliated with the University of Maryland, Baltimore County in the United States. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with an emphasis on Molecular Biology as a subfield. Their work spans a range of topics related to RNA and protein synthesis mechanisms, RNA modifications and cancer, molecular biology techniques, CRISPR and genetic engineering, peptidase inhibition and analysis, signaling pathways in disease, and natural language processing techniques.

Farabaugh has contributed to several recent scientific publications, including:

  • Guidelines for minimal reporting requirements, design and interpretation of experiments involving the use of eukaryotic dual gene expression reporters (MINDR), 2025, Nature Structural & Molecular Biology
  • Posttranscriptional modification to the core of tRNAs modulates translational misreading errors, 2023, RNA
  • Translon: a single term for translated regions, 2025, Nature Methods
  • An evolutionarily conserved phosphoserine-arginine salt bridge in the interface between ribosomal proteins uS4 and uS5 regulates translational accuracy in Saccharomyces cerevisiae, 2024, Nucleic Acids Research
  • Novel Reporter System to Quantify Missense Errors During Translation in Saccharomyces cerevisiae, 2025, Journal of Science Technology Education Art and Medicine

These publications have appeared in journals such as Nature Structural & Molecular Biology, RNA, Nature Methods, Nucleic Acids Research, and the Journal of Science Technology Education Art and Medicine. The scientist frequently collaborates with several peers, including Gary Loughran, Dmitry E. Andreev, Olivier Namy, Martin Mikl, and C. Joel McManus.

The main fields of study shaping Farabaugh's research are interconnected with their investigations into genetic translation accuracy, RNA biology, and molecular mechanisms underlying cellular processes. Their range of expertise also extends into cancer-related RNA modifications and advanced molecular biology techniques, providing a multidisciplinary approach to their scientific inquiries.

Best Publications

  • Molecular basis of base substitution hotspots in Escherichia coli.

    Christine Coulondre;Jeffrey H. Miller;Philip J. Farabaugh;Walter Gilbert

  • Programmed translational frameshifting.

    Farabaugh Pj

  • Genetic studies of the lac repressor: VII. On the molecular nature of spontaneous hotspots in the lacI gene of Escherichia coli

    Philip J. Farabaugh;Ursula Schmeissner;Murielle Hofer;Jeffrey H. Miller

  • Sequence of the lacI gene.

    Philip J. Farabaugh;Philip J. Farabaugh

  • The frequency of translational misreading errors in E. coli is largely determined by tRNA competition.

    Emily B. Kramer;Philip J. Farabaugh

  • Nucleotide sequence of a yeast Ty element: evidence for an unusual mechanism of gene expression

    Jeffrey Clare;Philip Farabaugh

  • Ribosomal frameshifting in the yeast retrotransposon Ty: tRNAs induce slippage on a 7 nucleotide minimal site

    Michael F. Belcourt;Philip J. Farabaugh

  • Insertion of the eukaryotic transposable element Ty1 creates a 5-base pair duplication.

    Philip J. Farabaugh;Gerald R. Fink

  • Oncogenic role of DDX3 in breast cancer biogenesis

    M Botlagunta;F Vesuna;Y Mironchik;A Raman

  • The nucleotide sequence of the HIS4 region of yeast.

    Thomas F. Donahue;Philip J. Farabaugh;Gerald R. Fink

  • The Origins of Gene Instability in Yeast

    GS Roeder;PJ Farabaugh;DT Chaleff;GR Fink

  • A novel programed frameshift expresses the POL3 gene of retrotransposon Ty3 of yeast: Frameshifting without tRNA slippage

    Philip J. Farabaugh;Hong Zhao;Arunachalam Vimaladithan

  • How translational accuracy influences reading frame maintenance.

    Philip J. Farabaugh;Glenn R. Björk

  • Protein mistranslation: friend or foe?

    Liuís Ribas de Pouplana;Manuel A.S. Santos;Jun-Hao Zhu;Philip J. Farabaugh

  • A rare tRNA-Arg(CCU) that regulates Ty1 element ribosomal frameshifting is essential for Ty1 retrotransposition in Saccharomyces cerevisiae.

    K Kawakami;S Pande;Brenda Faiola;DP Moore

  • A comprehensive analysis of translational missense errors in the yeast Saccharomyces cerevisiae.

    Emily B. Kramer;Haritha Vallabhaneni;Lauren M. Mayer;Philip J. Farabaugh

  • Efficient translational frameshifting occurs within a conserved sequence of the overlap between the two genes of a yeast Ty1 transposon

    J J Clare;M Belcourt;P J Farabaugh

  • A New Model for Phenotypic Suppression of Frameshift Mutations by Mutant tRNAs

    Qiang Qian;Ji-nong Li;Hong Zhao;Tord G. Hagervall

  • Translational frameshifting: implications for the mechanism of translational frame maintenance.

    Philip J. farabaugh

  • New ways of initiating translation in eukaryotes? [2](multiple letters)

    R. Schneider;V. I. Agol;R. Andino;F. Bayard

Frequent Co-Authors

Glenn R. Björk
Glenn R. Björk Umeå University
David J. Garfinkel
David J. Garfinkel University of Georgia
David M. Bedwell
David M. Bedwell University of Alabama at Birmingham
Richard J. Maraia
Richard J. Maraia National Institutes of Health
Fred Winston
Fred Winston Harvard University
Susan W. Liebman
Susan W. Liebman University of Nevada Reno
Walter Gilbert
Walter Gilbert Harvard University
Jef D. Boeke
Jef D. Boeke New York University
Koichi Kawakami
Koichi Kawakami National Institute of Genetics

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