1983 - Fellow of John Simon Guggenheim Memorial Foundation
His primary scientific interests are in Biochemistry, Cardiolipin, Cell biology, Phosphatidylglycerol and Membrane protein. Phosphatidylethanolamine, Phospholipid, Mutant, Saccharomyces cerevisiae and Escherichia coli are among the areas of Biochemistry where William Dowhan concentrates his study. His Phospholipid study integrates concerns from other disciplines, such as Golgi apparatus, Secretory protein and Liposome.
His research investigates the connection between Escherichia coli and topics such as Biosynthesis that intersect with problems in Acridine orange and Function. The various areas that William Dowhan examines in his Cardiolipin study include Cytochrome c, Mitochondrion, Inner mitochondrial membrane, Cytochrome and ATP synthase. The concepts of his Membrane transport protein study are interwoven with issues in Chaperone and Membrane lipids.
William Dowhan mostly deals with Biochemistry, Cardiolipin, Phosphatidylethanolamine, Cell biology and Phospholipid. His research brings together the fields of Molecular biology and Biochemistry. His Cardiolipin study combines topics in areas such as Coenzyme Q – cytochrome c reductase, Mitochondrion, Inner mitochondrial membrane, Phosphatidylglycerol and ATP synthase.
His Phosphatidylethanolamine research is multidisciplinary, incorporating elements of Cell membrane, Membrane permeability, Lactose permease, Membrane protein and Membrane lipids. His study in Membrane protein is interdisciplinary in nature, drawing from both Biophysics and Transmembrane domain. His work carried out in the field of Phospholipid brings together such families of science as Liposome, Cell division and Yeast.
His primary areas of study are Biochemistry, Membrane protein, Phosphatidylethanolamine, Cardiolipin and Cell biology. His work on Peripheral membrane protein as part of general Membrane protein research is frequently linked to Topology, bridging the gap between disciplines. William Dowhan has included themes like Periplasmic space, Membrane lipids and Lactose permease in his Phosphatidylethanolamine study.
His Cardiolipin research integrates issues from Coenzyme Q – cytochrome c reductase, Mutant, Mitochondrion, Inner membrane and Phosphatidylglycerol. His Cell biology research includes elements of Hypoxia, Glycolysis, Sphingosine, Membrane fluidity and Lipid bilayer. His Phospholipid research incorporates themes from Cytoplasm, Cell envelope and Function.
His main research concerns Biochemistry, Phosphatidylethanolamine, Cardiolipin, Membrane protein and Lactose permease. His biological study spans a wide range of topics, including Hypoxia and Cell biology. His studies deal with areas such as Phosphatidylglycerol, Coenzyme Q – cytochrome c reductase, Mutant and Mitochondrion as well as Cardiolipin.
In his study, which falls under the umbrella issue of Membrane protein, Protein folding, Transmembrane protein and Transport protein is strongly linked to Transmembrane domain. His research in Lactose permease intersects with topics in Protein structure, Biophysics and Membrane lipids. Many of his research projects under Phospholipid are closely connected to Cell wall thickening with Cell wall thickening, tying the diverse disciplines of science together.
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MOLECULAR BASIS FOR MEMBRANE PHOSPHOLIPID DIVERSITY: Why Are There So Many Lipids?
Annual Review of Biochemistry (1997)
An essential role for a phospholipid transfer protein in yeast Golgi function.
Vytas A. Bankaitis;Jacqueline R. Aitken;Ann E. Cleves;William Dowhan.
The ATPase activity of secA is regulated by acidic phospholipids, secY, and the leader and mature domains of precursor proteins
Roland Lill;William Dowhan;William Wickner.
Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane.
Mei Zhang;Eugenia Mileykovskaya;William Dowhan.
Journal of Biological Chemistry (2002)
Visualization of phospholipid domains in Escherichia coli by using the cardiolipin-specific fluorescent dye 10-N-nonyl acridine orange.
Eugenia Mileykovskaya;William Dowhan.
Journal of Bacteriology (2000)
Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein.
Ann E. Cleves;Todd P. McGee;Eric A. Whitters;Kathleen M. Champlon.
Decreased cardiolipin synthesis corresponds with cytochrome c release in palmitate-induced cardiomyocyte apoptosis.
Darin B. Ostrander;Darin B. Ostrander;Genevieve C. Sparagna;Genevieve C. Sparagna;Andrew A. Amoscato;Jeanie B. McMillin;Jeanie B. McMillin.
Journal of Biological Chemistry (2001)
Cardiolipin membrane domains in prokaryotes and eukaryotes.
Eugenia Mileykovskaya;William Dowhan.
Biochimica et Biophysica Acta (2009)
Cardiolipin and apoptosis.
Jeanie B McMillin;William Dowhan.
Biochimica et Biophysica Acta (2002)
Biosynthesis and function of phospholipids in Escherichia coli.
Christian R H Raetz;William Dowhan.
Journal of Biological Chemistry (1990)
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