D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 78 Citations 18,420 189 World Ranking 2878 National Ranking 1519

Research.com Recognitions

Awards & Achievements

1983 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • DNA

His primary scientific interests are in Biochemistry, Cardiolipin, Cell biology, Phosphatidylglycerol and Membrane protein. Phosphatidylethanolamine, Phospholipid, Mutant, Saccharomyces cerevisiae and Escherichia coli are among the areas of Biochemistry where William Dowhan concentrates his study. His Phospholipid study integrates concerns from other disciplines, such as Golgi apparatus, Secretory protein and Liposome.

His research investigates the connection between Escherichia coli and topics such as Biosynthesis that intersect with problems in Acridine orange and Function. The various areas that William Dowhan examines in his Cardiolipin study include Cytochrome c, Mitochondrion, Inner mitochondrial membrane, Cytochrome and ATP synthase. The concepts of his Membrane transport protein study are interwoven with issues in Chaperone and Membrane lipids.

His most cited work include:

  • MOLECULAR BASIS FOR MEMBRANE PHOSPHOLIPID DIVERSITY: Why Are There So Many Lipids? (764 citations)
  • Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane. (498 citations)
  • The ATPase activity of secA is regulated by acidic phospholipids, secY, and the leader and mature domains of precursor proteins (486 citations)

What are the main themes of his work throughout his whole career to date?

William Dowhan mostly deals with Biochemistry, Cardiolipin, Phosphatidylethanolamine, Cell biology and Phospholipid. His research brings together the fields of Molecular biology and Biochemistry. His Cardiolipin study combines topics in areas such as Coenzyme Q – cytochrome c reductase, Mitochondrion, Inner mitochondrial membrane, Phosphatidylglycerol and ATP synthase.

His Phosphatidylethanolamine research is multidisciplinary, incorporating elements of Cell membrane, Membrane permeability, Lactose permease, Membrane protein and Membrane lipids. His study in Membrane protein is interdisciplinary in nature, drawing from both Biophysics and Transmembrane domain. His work carried out in the field of Phospholipid brings together such families of science as Liposome, Cell division and Yeast.

He most often published in these fields:

  • Biochemistry (60.51%)
  • Cardiolipin (29.23%)
  • Phosphatidylethanolamine (25.13%)

What were the highlights of his more recent work (between 2009-2021)?

  • Biochemistry (60.51%)
  • Membrane protein (21.03%)
  • Phosphatidylethanolamine (25.13%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Biochemistry, Membrane protein, Phosphatidylethanolamine, Cardiolipin and Cell biology. His work on Peripheral membrane protein as part of general Membrane protein research is frequently linked to Topology, bridging the gap between disciplines. William Dowhan has included themes like Periplasmic space, Membrane lipids and Lactose permease in his Phosphatidylethanolamine study.

His Cardiolipin research integrates issues from Coenzyme Q – cytochrome c reductase, Mutant, Mitochondrion, Inner membrane and Phosphatidylglycerol. His Cell biology research includes elements of Hypoxia, Glycolysis, Sphingosine, Membrane fluidity and Lipid bilayer. His Phospholipid research incorporates themes from Cytoplasm, Cell envelope and Function.

Between 2009 and 2021, his most popular works were:

  • Cardiolipin-dependent formation of mitochondrial respiratory supercomplexes. (159 citations)
  • Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates (148 citations)
  • Mitochondrial Phosphatase PTPMT1 Is Essential for Cardiolipin Biosynthesis (127 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • DNA

His main research concerns Biochemistry, Phosphatidylethanolamine, Cardiolipin, Membrane protein and Lactose permease. His biological study spans a wide range of topics, including Hypoxia and Cell biology. His studies deal with areas such as Phosphatidylglycerol, Coenzyme Q – cytochrome c reductase, Mutant and Mitochondrion as well as Cardiolipin.

In his study, which falls under the umbrella issue of Membrane protein, Protein folding, Transmembrane protein and Transport protein is strongly linked to Transmembrane domain. His research in Lactose permease intersects with topics in Protein structure, Biophysics and Membrane lipids. Many of his research projects under Phospholipid are closely connected to Cell wall thickening with Cell wall thickening, tying the diverse disciplines of science together.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

MOLECULAR BASIS FOR MEMBRANE PHOSPHOLIPID DIVERSITY: Why Are There So Many Lipids?

William Dowhan.
Annual Review of Biochemistry (1997)

1069 Citations

An essential role for a phospholipid transfer protein in yeast Golgi function.

Vytas A. Bankaitis;Jacqueline R. Aitken;Ann E. Cleves;William Dowhan.
Nature (1990)

654 Citations

The ATPase activity of secA is regulated by acidic phospholipids, secY, and the leader and mature domains of precursor proteins

Roland Lill;William Dowhan;William Wickner.
Cell (1990)

651 Citations

Gluing the respiratory chain together. Cardiolipin is required for supercomplex formation in the inner mitochondrial membrane.

Mei Zhang;Eugenia Mileykovskaya;William Dowhan.
Journal of Biological Chemistry (2002)

632 Citations

Visualization of phospholipid domains in Escherichia coli by using the cardiolipin-specific fluorescent dye 10-N-nonyl acridine orange.

Eugenia Mileykovskaya;William Dowhan.
Journal of Bacteriology (2000)

458 Citations

Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein.

Ann E. Cleves;Todd P. McGee;Eric A. Whitters;Kathleen M. Champlon.
Cell (1991)

411 Citations

Decreased cardiolipin synthesis corresponds with cytochrome c release in palmitate-induced cardiomyocyte apoptosis.

Darin B. Ostrander;Darin B. Ostrander;Genevieve C. Sparagna;Genevieve C. Sparagna;Andrew A. Amoscato;Jeanie B. McMillin;Jeanie B. McMillin.
Journal of Biological Chemistry (2001)

373 Citations

Cardiolipin membrane domains in prokaryotes and eukaryotes.

Eugenia Mileykovskaya;William Dowhan.
Biochimica et Biophysica Acta (2009)

346 Citations

Cardiolipin and apoptosis.

Jeanie B McMillin;William Dowhan.
Biochimica et Biophysica Acta (2002)

343 Citations

Biosynthesis and function of phospholipids in Escherichia coli.

Christian R H Raetz;William Dowhan.
Journal of Biological Chemistry (1990)

330 Citations

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