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Medicine

D-Index
85
Citations
39523
World Ranking
14391
National Ranking
7277

Overview

Wolfgang J. Streit is affiliated with the University of Florida in the United States and has contributed extensively to the fields of neuroscience and medicine, with a particular focus on neurology, immunology, and cellular and molecular neuroscience. Their research addresses key topics including neuroinflammation and neurodegeneration mechanisms, Alzheimer's disease research and treatments, nuclear receptors and signaling, as well as immune cell function and interaction.

Among their recent publications are significant papers such as:

  • "Microglia states and nomenclature: A field at its crossroads," 2022, published in Neuron
  • "Beyond Activation: Characterizing Microglial Functional Phenotypes," 2021, published in Cells
  • "Dystrophic microglia in late-onset Alzheimer's disease," 2020, published in Glia
  • "The Role of Microglia in Sporadic Alzheimer's Disease," 2021, published in Journal of Alzheimer s Disease
  • "Microglia senescence occurs in both substantia nigra and ventral tegmental area," 2020, published in Glia

These papers reflect ongoing research interests centered on microglial function and senescence within the context of neurodegenerative diseases such as Alzheimer's disease. Their investigation of microglia aligns with broader studies of neurological disease mechanisms and treatments.

Their frequent co-authors include:

  • Habibeh Khoshbouei
  • Ingo Bechmann
  • Adithya Gopinath
  • Phillip Mackie
  • Adolfo Ramirez-Zamora

Wolfgang J. Streit has published in venues that are prominent within neuroscience and neurodegenerative disease research, including multiple contributions to Glia, Journal of Alzheimer s Disease, and npj Parkinson s Disease. Other publication venues include bioRxiv (Cold Spring Harbor Laboratory) and Neuron.

Their work covers multiple subfields including molecular biology and physiology, which supports a comprehensive approach to understanding cellular and molecular processes underlying neurological conditions.

Best Publications

  • Inflammation and Alzheimer's disease.

    H Akiyama;S Barger;S Barnum;B Bradt

  • Down-Regulation of the Macrophage Lineage Through Interaction with OX2 (CD200)

    Robert M. Hoek;Sigrid R. Ruuls;Craig A. Murphy;Gavin J. Wright

  • Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia

    Jeffrey K. Harrison;Yan Jiang;Shizong Chen;Yiyang Xia

  • Microglia as neuroprotective, immunocompetent cells of the CNS

    Wolfgang J. Streit

  • Functional plasticity of microglia: a review.

    Wolfgang J. Streit;Manuel B. Graeber;Georg W. Kreutzberg

  • Microglia and neuroinflammation: a pathological perspective

    Wolfgang J Streit;Robert E Mrak;W Sue T Griffin

  • Microglia: biology and pathology

    Manuel B. Graeber;Wolfgang J. Streit

  • Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease.

    Wolfgang J. Streit;Heiko Braak;Heiko Braak;Qing-Shan Xue;Ingo Bechmann

  • Dystrophic microglia in the aging human brain.

    Wolfgang J. Streit;Nicole W. Sammons;Amanda J. Kuhns;D. Larry Sparks

  • Lectin binding by resting and reactive microglia.

    Wolfgang J. Streit;Georg W. Kreutzberg

  • Response of endogenous glial cells to motor neuron degeneration induced by toxic ricin.

    Wolfgang J. Streit;Georg W. Kreutzberg

  • An Improved Staining Method for Rat Microglial Cells Using the Lectin from Griffonia simplicifolia (GSA I-B4)

    Wolfgang J. Streit

  • Microglial senescence: does the brain's immune system have an expiration date?

    Wolfgang J. Streit

  • Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells

    M. B. Graeber;W. J. Streit;G. W. Kreutzberg

  • Microglia and Alzheimer's disease pathogenesis.

    Wolfgang J. Streit

  • Microglia in the aging brain.

    Jessica R. Conde;Wolfgang J. Streit

  • The microglial reaction in the rat dorsal hippocampus following transient forebrain ischemia.

    Takato Morioka;Audrey N. Kalehua;Wolfgang J. Streit

  • Cytokine mRNA Profiles in Contused Spinal Cord and Axotomized Facial Nucleus Suggest a Beneficial Role for Inflammation and Gliosis

    Wolfgang J. Streit;Susan L. Semple-Rowland;Sean D. Hurley;Rehae C. Miller

  • Microglial cells but not astrocytes undergo mitosis following rat facial nerve axotomy

    Manuel B. Graeber;Wolfram Tetzlaff;Wolfgang J. Streit;Georg W. Kreutzberg

  • Characterization of microglial reaction after middle cerebral artery occlusion in rat brain

    Takato Morioka;Audrey N. Kalehua;Wolfgang J. Streit

Frequent Co-Authors

Georg W. Kreutzberg
Georg W. Kreutzberg Max Planck Society
Gerry Shaw
Gerry Shaw University of Florida
Toshikazu Nishida
Toshikazu Nishida University of Florida
Alexander G. Rabchevsky
Alexander G. Rabchevsky University of Kentucky
Heiko Braak
Heiko Braak University of Ulm
Ingo Bechmann
Ingo Bechmann Leipzig University
Michael S. Okun
Michael S. Okun University of Florida
Steven N. Roper
Steven N. Roper University of Florida
Phillip G. Popovich
Phillip G. Popovich The Ohio State University

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