H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Medicine D-index 74 Citations 14,867 185 World Ranking 12484 National Ranking 37

Research.com Recognitions

Awards & Achievements

2009 - Member of the Royal Irish Academy

Overview

What is she best known for?

The fields of study she is best known for:

  • Internal medicine
  • Cytokine
  • Biochemistry

Her primary scientific interests are in Long-term potentiation, Internal medicine, Endocrinology, Hippocampus and Dentate gyrus. Her studies in Long-term potentiation integrate themes in fields like Hippocampal formation, Glutamate receptor, Proinflammatory cytokine and Immunology. The various areas that Marina A. Lynch examines in her Internal medicine study include Kinase and p38 mitogen-activated protein kinases.

She interconnects Caspase 3, Apoptosis and Glutamic acid in the investigation of issues within Endocrinology. Her Hippocampus research is multidisciplinary, incorporating perspectives in Synaptic plasticity and Neuroplasticity. Her work in Dentate gyrus addresses issues such as Entorhinal cortex, which are connected to fields such as Perforant Pathway and Pyramidal cell.

Her most cited work include:

  • Long-Term Potentiation and Memory (1483 citations)
  • Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus. (561 citations)
  • Evidence That Increased Hippocampal Expression of the Cytokine Interleukin-1β Is a Common Trigger for Age- and Stress-Induced Impairments in Long-Term Potentiation (376 citations)

What are the main themes of her work throughout her whole career to date?

Marina A. Lynch mainly investigates Long-term potentiation, Endocrinology, Internal medicine, Hippocampus and Neuroscience. Her Long-term potentiation research includes themes of Dentate gyrus, Glutamate receptor, Immunology and Synaptic plasticity. Her Endocrinology study also includes

  • Receptor, which have a strong connection to Cell biology,
  • Protein kinase A together with Reactive oxygen species.

Internal medicine is often connected to Protein kinase C in her work. Her Hippocampus study deals with Hippocampal formation intersecting with Lipopolysaccharide. Her Neuroscience research integrates issues from NMDA receptor, Neuroinflammation, Microglia and Postsynaptic potential.

She most often published in these fields:

  • Long-term potentiation (41.26%)
  • Endocrinology (41.26%)
  • Internal medicine (41.26%)

What were the highlights of her more recent work (between 2011-2020)?

  • Immunology (24.16%)
  • Microglia (19.70%)
  • Neuroinflammation (13.75%)

In recent papers she was focusing on the following fields of study:

Marina A. Lynch spends much of her time researching Immunology, Microglia, Neuroinflammation, Cell biology and Neuroscience. Her Immunology research is multidisciplinary, incorporating perspectives in Endocrinology and Internal medicine, Disease. Her research in Microglia intersects with topics in Proinflammatory cytokine, Long-term potentiation, Phagocytosis and Neurodegeneration.

Long-term potentiation is a subfield of Biochemistry that Marina A. Lynch investigates. Her Cell biology research includes themes of Receptor, Inflammasome, Oxidative phosphorylation and Neuroglia. In her study, Neuroplasticity is inextricably linked to Hippocampus, which falls within the broad field of Neuroprotection.

Between 2011 and 2020, her most popular works were:

  • Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice. (170 citations)
  • IFN-γ Production by Amyloid β–Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer’s Disease (153 citations)
  • Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP. (116 citations)

In her most recent research, the most cited papers focused on:

  • Internal medicine
  • Cytokine
  • Immune system

Her primary areas of study are Immunology, Microglia, Neuroinflammation, Cell biology and Proinflammatory cytokine. Her Immunology study combines topics in areas such as Long-term potentiation, Endocrinology and Internal medicine. Her biological study focuses on Hippocampus.

Marina A. Lynch interconnects Alzheimer's disease, Disease, Neurodegeneration and Lipopolysaccharide in the investigation of issues within Microglia. Her Neuroinflammation research incorporates themes from Caspase 1, Neuroscience, Janus kinase and Cognitive decline. Her work carried out in the field of Cell biology brings together such families of science as Oxidative phosphorylation and Astrocyte.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Long-Term Potentiation and Memory

M. A. Lynch.
Physiological Reviews (2004)

2189 Citations

Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus.

J. H. Williams;M. L. Errington;M. A. Lynch;T. V. P. Bliss.
Nature (1989)

693 Citations

Evidence That Increased Hippocampal Expression of the Cytokine Interleukin-1β Is a Common Trigger for Age- and Stress-Induced Impairments in Long-Term Potentiation

Ciara A. Murray;Marina A. Lynch.
The Journal of Neuroscience (1998)

467 Citations

Interleukin-1β (IL-1β) and tumour necrosis factor (TNF) inhibit long-term potentiation in the rat dentate gyrus in vitro

A.J. Cunningham;C.A. Murray;L.A.J. O'Neill;M.A. Lynch.
Neuroscience Letters (1996)

460 Citations

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis.

Áine C. Murphy;Stephen J. Lalor;Marina A. Lynch;Kingston H.G. Mills.
Brain Behavior and Immunity (2010)

367 Citations

Correlation between long-term potentiation and release of endogenous amino acids from dentate gyrus of anaesthetized rats.

T V Bliss;R M Douglas;M L Errington;M A Lynch.
The Journal of Physiology (1986)

354 Citations

Long-term potentiation in the dentate gyrus: induction and increased glutamate release are blocked by D(-)aminophosphonovalerate.

M.L. Errington;M.A. Lynch;T.V.P. Bliss.
Neuroscience (1987)

331 Citations

The multifaceted profile of activated microglia.

Marina A. Lynch.
Molecular Neurobiology (2009)

312 Citations

Age-related changes in synaptic function: analysis of the effect of dietary supplementation with ω-3 fatty acids

B.M McGahon;D.S.D Martin;D.F Horrobin;M.A Lynch.
Neuroscience (1999)

272 Citations

The Inhibitory Effect of Interleukin-1β on Long-Term Potentiation Is Coupled with Increased Activity of Stress-Activated Protein Kinases

E. Vereker;E. O'Donnell;M. A. Lynch.
The Journal of Neuroscience (2000)

272 Citations

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