Marina A. Lynch

Research.com Recognitions

• 2026 - Research.com Neuroscience in Ireland Leader Award
• 2025 - Research.com Neuroscience in Ireland Leader Award
• 2009 - Member of the Royal Irish Academy

Overview

Best Publications

• Long-Term Potentiation and Memory

  M. A. Lynch

  2605
  Citations

• Arachidonic acid induces a long-term activity-dependent enhancement of synaptic transmission in the hippocampus.

  J. H. Williams;M. L. Errington;M. A. Lynch;T. V. P. Bliss

  699
  Citations

• Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice.

  C. Dempsey;A. Rubio Araiz;K.J. Bryson;O. Finucane

  557
  Citations

• Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis.

  Áine C. Murphy;Stephen J. Lalor;Marina A. Lynch;Kingston H.G. Mills

  546
  Citations

• Interleukin-1β (IL-1β) and tumour necrosis factor (TNF) inhibit long-term potentiation in the rat dentate gyrus in vitro

  A.J. Cunningham;C.A. Murray;L.A.J. O'Neill;M.A. Lynch

  525
  Citations

• Evidence That Increased Hippocampal Expression of the Cytokine Interleukin-1β Is a Common Trigger for Age- and Stress-Induced Impairments in Long-Term Potentiation

  Ciara A. Murray;Marina A. Lynch

  512
  Citations

• Correlation between long-term potentiation and release of endogenous amino acids from dentate gyrus of anaesthetized rats.

  T V Bliss;R M Douglas;M L Errington;M A Lynch

  385
  Citations

• The multifaceted profile of activated microglia.

  Marina A. Lynch

  379
  Citations

• Long-term potentiation in the dentate gyrus: induction and increased glutamate release are blocked by D(-)aminophosphonovalerate.

  M.L. Errington;M.A. Lynch;T.V.P. Bliss

  353
  Citations

• CD200 Ligand–Receptor Interaction Modulates Microglial Activation In Vivo and In Vitro: A Role for IL-4

  Anthony Lyons;Eric J Downer;Suzanne Crotty;Yvonne M Nolan

  328
  Citations

• IFN-γ Production by Amyloid β–Specific Th1 Cells Promotes Microglial Activation and Increases Plaque Burden in a Mouse Model of Alzheimer’s Disease

  Tara C. Browne;Keith McQuillan;Róisín M. McManus;Julie-Ann O’Reilly

  327
  Citations

• The age-related attenuation in long-term potentiation is associated with microglial activation.

  Rebecca Griffin;Rachel Nally;Yvonne Nolan;Yvonne McCartney

  318
  Citations

• The Inhibitory Effect of Interleukin-1β on Long-Term Potentiation Is Coupled with Increased Activity of Stress-Activated Protein Kinases

  E. Vereker;E. O'Donnell;M. A. Lynch

  299
  Citations

• Age-related changes in synaptic function: analysis of the effect of dietary supplementation with ω-3 fatty acids

  B.M McGahon;D.S.D Martin;D.F Horrobin;M.A Lynch

  298
  Citations

• Modulation of intestinal microbiota by the probiotic VSL#3 resets brain gene expression and ameliorates the age-related deficit in LTP.

  Eleonora Distrutti;Julie-Ann O’Reilly;Claire McDonald;Sabrina Cipriani

  267
  Citations

• Fractalkine-induced activation of the phosphatidylinositol-3 kinase pathway attentuates microglial activation in vivo and in vitro.

  Anthony Lyons;Aileen M. Lynch;Eric J. Downer;Riona Hanley

  266
  Citations

• Role of interleukin-4 in regulation of age-related inflammatory changes in the hippocampus.

  Yvonne Nolan;Frank O. Maher;Darren S. Martin;Rachael M. Clarke

  265
  Citations

• Age-related impairment in long-term potentiation in hippocampus: a role for the cytokine, interleukin-1 beta?

  Marina A Lynch

  238
  Citations

• Lipopolysaccharide Inhibits Long Term Potentiation in the Rat Dentate Gyrus by Activating Caspase-1

  Emily Vereker;Veronica Campbell;Elizabeth Roche;Edel McEntee

  224
  Citations

• Nordihydroguaiaretic acid blocks the synaptic component of long-term potentiation and the associated increases in release of glutamate and arachidonate: an in vivo study in the dentate gyrus of the rat.

  M.A. Lynch;M.L. Errington;T.V.P. Bliss

  224
  Citations