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Best Female Scientists

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106
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Neuroscience

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106
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Overview

Annamaria Vezzani is affiliated with the Mario Negri Institute for Pharmacological Research in Italy. Their research primarily focuses on medicine and neuroscience, with extensive contributions in the fields of psychiatry and mental health, cellular and molecular neuroscience, neurology, pediatrics, perinatology, child health, and molecular biology.

The principal topics covered in their work include epilepsy research and treatment, neuroscience and neuropharmacology research, neuroinflammation and neurodegeneration mechanisms, pharmacological effects and toxicity studies, drug transport and resistance mechanisms, neonatal and fetal brain pathology, and infectious encephalopathies and encephalitis.

Key research papers include:

  • "Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment Options," 2020, Pharmacological Reviews
  • "White matter abnormalities across different epilepsy syndromes in adults: an ENIGMA-Epilepsy study," 2020, Brain
  • "Astrocytes in the initiation and progression of epilepsy," 2022, Nature Reviews Neurology
  • "Repurposed molecules for antiepileptogenesis: Missing an opportunity to prevent epilepsy?" 2020, Epilepsia
  • "mTOR and neuroinflammation in epilepsy: implications for disease progression and treatment," 2024, Nature Reviews Neuroscience

Frequent coauthors in their research include Teresa Ravizza, Rossella Di Sapia, Eleonora Aronica, Silvia Balosso, and Sanjay M. Sisodiya. Their collaborative efforts have yielded numerous publications and advanced studies related to epilepsy and neuroinflammation.

The scientist often publishes in venues that include:

  • Epilepsia
  • Neurobiology of Disease
  • Epilepsia Open
  • Zenodo (CERN European Organization for Nuclear Research)
  • Brain

Their research addresses molecular and cellular mechanisms underlying neurological diseases, with a particular focus on epilepsy pathophysiology, disease progression, and therapeutic development. Such contributions involve studying neuroinflammatory pathways and drug resistance phenomena in epilepsy, along with potential treatments to influence disease trajectory and outcomes.

Best Publications

  • The role of inflammation in epilepsy

    Annamaria Vezzani;Jacqueline French;Tamas Bartfai;Tallie Z. Baram

  • The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission

    Ingmar Blümcke;Maria Thom;Eleonora Aronica;Dawna D. Armstrong

  • Brain inflammation in epilepsy: experimental and clinical evidence.

    Annamaria Vezzani;Tiziana Granata

  • Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases

    Barbara Viviani;S. Bartesaghi;F. Gardoni;A. Vezzani

  • Epilepsy

    Unknown

  • Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

    Mattia Maroso;Silvia Balosso;Teresa Ravizza;Jaron Liu

  • Glia and epilepsy: excitability and inflammation

    Orrin Devinsky;Annamaria Vezzani;Souhel Najjar;Nihal C. De Lanerolle

  • Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy.

    Annamaria Vezzani;Silvia Balosso;Teresa Ravizza

  • Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain.

    Anna L. M. Ferri;Maurizio Cavallaro;Daniela Braida;Antonello Di Cristofano

  • Innate and adaptive immunity during epileptogenesis and spontaneous seizures: Evidence from experimental models and human temporal lobe epilepsy

    Teresa Ravizza;Barbara Gagliardi;Francesco Noé;Karin Boer

  • Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment Options.

    Wolfgang Löscher;Heidrun Potschka;Sanjay M. Sisodiya;Annamaria Vezzani

  • Interleukin-1β Immunoreactivity and Microglia Are Enhanced in the Rat Hippocampus by Focal Kainate Application: Functional Evidence for Enhancement of Electrographic Seizures

    Annamaria Vezzani;Mirko Conti;Ada De Luigi;Teresa Ravizza

  • Neuromodulatory properties of inflammatory cytokines and their impact on neuronal excitability.

    Annamaria Vezzani;Barbara Viviani

  • Inflammatory cytokines and related genes are induced in the rat hippocampus by limbic status epilepticus

    Maria Grazia De Simoni;Carlo Perego;Teresa Ravizza;Daniela Moneta

  • Epilepsy and brain inflammation.

    Annamaria Vezzani;Eleonora Aronica;Andrey Mazarati;Quentin J. Pittman

  • The role of cytokines in the pathophysiology of epilepsy.

    Annamaria Vezzani;Silvia Balosso;Teresa Ravizza

  • Infections, inflammation and epilepsy

    Annamaria Vezzani;Robert S. Fujinami;H. Steve White;Pierre Marie Preux

  • Powerful anticonvulsant action of IL-1 receptor antagonist on intracerebral injection and astrocytic overexpression in mice.

    A. Vezzani;D. Moneta;M. Conti;C. Richichi

  • The role of inflammation in epileptogenesis

    Annamaria Vezzani;Alon Friedman;Raymond J. Dingledine

  • Neuropeptide Y: emerging evidence for a functional role in seizure modulation.

    Annamaria Vezzani;Günther Sperk;William F. Colmers

  • Interleukin-1β Contributes to the Generation of Experimental Febrile Seizures

    Celine Dubé;Annamaria Vezzani;Marga Behrens;Tamas Bartfai

Frequent Co-Authors

Teresa Ravizza
Teresa Ravizza Mario Negri Institute for Pharmacological Research
Eleonora Aronica
Eleonora Aronica University of Amsterdam
Rosario Samanin
Rosario Samanin Mario Negri Institute for Pharmacological Research
Günther Sperk
Günther Sperk Innsbruck Medical University
Alon Friedman
Alon Friedman Dalhousie University
Tamas Bartfai
Tamas Bartfai Stockholm University
Nicola Marchi
Nicola Marchi Centre national de la recherche scientifique, CNRS
Matthew J. During
Matthew J. During The Ohio State University
Merab Kokaia
Merab Kokaia Lund University
Khalid Hamandi
Khalid Hamandi Cardiff University

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