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57
Citations
11188
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4351
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132

Overview

Erwin A. van Vliet is affiliated with the University of Amsterdam in the Netherlands and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research predominantly focuses on neuroscience, epilepsy, and molecular mechanisms related to neurological disorders.

Their work encompasses several subfields of study, including molecular biology, physiology, cellular and molecular neuroscience, psychiatry and mental health, and pediatrics, perinatology, and child health. This diverse expertise reflects a broad approach to understanding neurological conditions at multiple biological levels.

Research topics covered by Erwin A. van Vliet include:

  • Neuroscience and neuropharmacology research
  • Epilepsy research and treatment
  • Pharmacological effects and toxicity studies
  • Tuberous sclerosis complex research
  • Metabolism and genetic disorders
  • Trace elements in health
  • MicroRNA in disease regulation

Among recent publications authored or co-authored by Erwin A. van Vliet, notable works include:

  • Long-lasting blood-brain barrier dysfunction and neuroinflammation after traumatic brain injury, 2020, Neurobiology of Disease
  • Neurovascular unit dysfunction as a mechanism of seizures and epilepsy during aging, 2022, Epilepsia

Frequent co-authors in their body of work include:

  • Eleonora Aronica
  • James D. Mills
  • Diede W. M. Broekaart
  • Jan A. Gorter
  • Jasper J. Anink

They have published regularly in journals with a focus on neurological disorders and molecular science, including:

  • Epilepsia
  • International Journal of Molecular Sciences
  • Neuropathology and Applied Neurobiology
  • Experimental Neurology
  • Epilepsia Open

This scientist's research is concentrated on critical issues such as blood-brain barrier integrity, neuroinflammation following brain injury, and mechanisms contributing to epileptogenesis and seizure pathology. Their work also explores the role of neurovascular dysfunction in aging-related epilepsy, contributing to a detailed understanding of neurobiological disease processes.

Best Publications

  • Blood–brain barrier leakage may lead to progression of temporal lobe epilepsy

    E. A. van Vliet;S. da Costa Araújo;S. Redeker;R. van Schaik

  • Progression of spontaneous seizures after status epilepticus is associated with mossy fibre sprouting and extensive bilateral loss of hilar parvalbumin and somatostatin-immunoreactive neurons.

    J. A. Gorter;E. A. Van Vliet;E. Aronica;F. H. Lopes Da Silva

  • Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy.

    Unknown

  • Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy.

    Eleonora Aronica;Erwin A. Van Vliet;Oleg A. Mayboroda;Dirk Troost

  • Potential New Antiepileptogenic Targets Indicated by Microarray Analysis in a Rat Model for Temporal Lobe Epilepsy

    Jan A Gorter;Erwin A van Vliet;Eleonora Aronica;Timo Breit

  • Expression pattern of miR‐146a, an inflammation‐associated microRNA, in experimental and human temporal lobe epilepsy

    E. Aronica;K. Fluiter;A. Iyer;E. Zurolo

  • Review: Neuroinflammatory pathways as treatment targets and biomarker candidates in epilepsy: emerging evidence from preclinical and clinical studies

    E A van Vliet;E Aronica;A Vezzani;T Ravizza

  • Blood–brain barrier dysfunction, seizures and epilepsy

    E.A. van Vliet;E. Aronica;J.A. Gorter

  • Complement activation in experimental and human temporal lobe epilepsy.

    E. Aronica;K. Boer;E.A. van Vliet;S. Redeker

  • Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation

    Erwin A. van Vliet;Grazia Forte;Linda Holtman;Jeroen C. G. den Burger

  • Inhibition of the Multidrug Transporter P-Glycoprotein Improves Seizure Control in Phenytoin-treated Chronic Epileptic Rats

    Erwin A. Van Vliet;Rosalinde Van Schaik;Peter M. Edelbroek;Sandra Redeker

  • Status epilepticus, blood-brain barrier disruption, inflammation, and epileptogenesis

    Jan A. Gorter;Erwin A. van Vliet;Eleonora Aronica

  • Targeting oxidative stress improves disease outcomes in a rat model of acquired epilepsy

    Alberto Pauletti;Gaetano Terrone;Tawfeeq Shekh-Ahmad;Alessia Salamone

  • Localization of breast cancer resistance protein (BCRP) in microvessel endothelium of human control and epileptic brain

    Eleonora Aronica;Jan A. Gorter;Sandra Redeker;Erwin A. Van Vliet

  • Hippocampal subregion-specific microRNA expression during epileptogenesis in experimental temporal lobe epilepsy

    Jan A. Gorter;Anand Iyer;Ian White;Anna Colzi

  • GABAA currents are decreased by IL-1β in epileptogenic tissue of patients with temporal lobe epilepsy: implications for ictogenesis.

    Cristina Roseti;Erwin A. van Vliet;Pierangelo Cifelli;Gabriele Ruffolo

  • COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats

    Erwin A. van Vliet;Guido Zibell;Anton Pekcec;Juli Schlichtiger

  • Neuronal cell death in a rat model for mesial temporal lobe epilepsy is induced by the initial status epilepticus and not by later repeated spontaneous seizures.

    Jan A. Gorter;Pedro M. Gonçalves Pereira;Erwin A. Van Vliet;Eleonora Aronica

  • Long-lasting blood-brain barrier dysfunction and neuroinflammation after traumatic brain injury

    Erwin A. van Vliet;Xavier Ekolle Ndode-Ekane;Lauri J. Lehto;Jan A. Gorter

  • Progression of temporal lobe epilepsy in the rat is associated with immunocytochemical changes in inhibitory interneurons in specific regions of the hippocampal formation

    Erwin A. van Vliet;Eleonora Aronica;Else A. Tolner;Fernando H. Lopes da Silva

  • Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy.

    Erwin A van Vliet;Eleonora Aronica;Sandra Redeker;Karin Boer

  • Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats.

    Erwin A. van Vliet;Sandra Redeker;Eleonora Aronica;Peter M. Edelbroek

Frequent Co-Authors

Eleonora Aronica
Eleonora Aronica University of Amsterdam
Jan A. Gorter
Jan A. Gorter University of Amsterdam
Wytse J. Wadman
Wytse J. Wadman University of Amsterdam
Annamaria Vezzani
Annamaria Vezzani Mario Negri Institute for Pharmacological Research
Asla Pitkänen
Asla Pitkänen University of Eastern Finland
Floor E. Jansen
Floor E. Jansen Utrecht University
Peter C. van Rijen
Peter C. van Rijen Utrecht University
Maria Thom
Maria Thom University College London Hospitals NHS Foundation Trust
Heidrun Potschka
Heidrun Potschka Ludwig-Maximilians-Universität München
Paul J. Lucassen
Paul J. Lucassen University of Amsterdam

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