D-Index & Metrics Best Publications
Neuroscience
Ireland
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 65 Citations 12,613 226 World Ranking 1837 National Ranking 3

Research.com Recognitions

Awards & Achievements

2023 - Research.com Neuroscience in Ireland Leader Award

2022 - Research.com Neuroscience in Ireland Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Internal medicine

David C. Henshall focuses on Epilepsy, Neuroscience, Status epilepticus, Hippocampal formation and Neuroprotection. His Epilepsy research is multidisciplinary, incorporating perspectives in Hippocampus, Neurodegeneration, Bioinformatics and Pathology. His Neuroscience research includes elements of Neuroinflammation and Programmed cell death.

His Status epilepticus research incorporates elements of Anticonvulsant, Gene silencing and Neocortex. The concepts of his Hippocampal formation study are interwoven with issues in Kainic acid and microRNA. His research integrates issues of Excitotoxicity, Dendritic spine and Ischemia, Ischemic preconditioning in his study of Neuroprotection.

His most cited work include:

  • Increased hippocampal neurogenesis in Alzheimer's disease (810 citations)
  • Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects (323 citations)
  • To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways (260 citations)

What are the main themes of his work throughout his whole career to date?

David C. Henshall mainly focuses on Epilepsy, Neuroscience, Status epilepticus, microRNA and Epileptogenesis. His Epilepsy research includes elements of Hippocampal formation, Hippocampus and Programmed cell death. His Hippocampal formation course of study focuses on Neurogenesis and Doublecortin.

His Neuroscience research also works with subjects such as

  • Neurodegeneration that intertwine with fields like Cancer research,
  • Epigenetics which is related to area like DNA methylation. His Status epilepticus research is multidisciplinary, relying on both Kainic acid, Neuroprotection, Pharmacology, Anticonvulsant and Gene silencing. His studies in microRNA integrate themes in fields like Biomarker, Gene expression and Bioinformatics.

He most often published in these fields:

  • Epilepsy (49.38%)
  • Neuroscience (39.92%)
  • Status epilepticus (35.39%)

What were the highlights of his more recent work (between 2018-2021)?

  • Epilepsy (49.38%)
  • microRNA (25.10%)
  • Neuroscience (39.92%)

In recent papers he was focusing on the following fields of study:

Epilepsy, microRNA, Neuroscience, Status epilepticus and Epileptogenesis are his primary areas of study. The study incorporates disciplines such as Biomarker, Regulation of gene expression, Hippocampus and Gene expression in addition to Epilepsy. His microRNA research is multidisciplinary, incorporating perspectives in Gene silencing, Downregulation and upregulation, Pathogenesis and Bioinformatics.

His study in the field of Hippocampal formation also crosses realms of Candesartan. His work carried out in the field of Status epilepticus brings together such families of science as Kainic acid, Programmed cell death, Pharmacology and Cell biology. His studies deal with areas such as Hippocampal sclerosis, Non-coding RNA and Gliosis as well as Epileptogenesis.

Between 2018 and 2021, his most popular works were:

  • Elevation in plasma tRNA fragments precede seizures in human epilepsy. (30 citations)
  • Elevated Plasma microRNA-206 Levels Predict Cognitive Decline and Progression to Dementia from Mild Cognitive Impairment. (14 citations)
  • Proteins and microRNAs are differentially expressed in tear fluid from patients with Alzheimer’s disease (14 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Internal medicine

His primary areas of investigation include microRNA, Epilepsy, Neuroscience, Epileptogenesis and Non-coding RNA. David C. Henshall is studying Temporal lobe, which is a component of Epilepsy. His work deals with themes such as Microglia, Neuroinflammation, Hypoxia and Cytokine, which intersect with Neuroscience.

His study looks at the relationship between Epileptogenesis and topics such as Hippocampal sclerosis, which overlap with Dentate gyrus, Brain stimulation and Hippocampus. His Non-coding RNA research integrates issues from Small RNA and Status epilepticus. The various areas that David C. Henshall examines in his Status epilepticus study include Kainic acid, Agonist, Metabotropic receptor and Anticonvulsant.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Increased hippocampal neurogenesis in Alzheimer's disease

Kunlin Jin;Alyson L. Peel;Xiao Ou Mao;Lin Xie.
Proceedings of the National Academy of Sciences of the United States of America (2004)

1192 Citations

Silencing microRNA-134 produces neuroprotective and prolonged seizure-suppressive effects

Eva M Jimenez-Mateos;Tobias Engel;Paula Merino-Serrais;Ross C McKiernan.
Nature Medicine (2012)

440 Citations

To die or not to die for neurons in ischemia, traumatic brain injury and epilepsy: a review on the stress-activated signaling pathways and apoptotic pathways

Anthony K.F Liou;Robert S Clark;David C Henshall;Xiao-Ming Yin.
Progress in Neurobiology (2003)

391 Citations

Activation of Bcl-2-Associated Death Protein and Counter-Response of Akt within Cell Populations during Seizure-Induced Neuronal Death

David C. Henshall;Tomohiro Araki;Clara K. Schindler;Jing-Quan Lan.
The Journal of Neuroscience (2002)

278 Citations

Epilepsy and apoptosis pathways.

David C Henshall;Roger P Simon.
Journal of Cerebral Blood Flow and Metabolism (2005)

266 Citations

Neuroprotective Actions of FK506 in Experimental Stroke: In Vivo Evidence against an Antiexcitotoxic Mechanism

Steven P. Butcher;David C. Henshall;Yoshinori Teramura;Kazuhide Iwasaki.
The Journal of Neuroscience (1997)

265 Citations

Endotoxin Preconditioning Prevents Cellular Inflammatory Response During Ischemic Neuroprotection in Mice

Holly L. Rosenzweig;Nikola S. Lessov;David C. Henshall;Manabu Minami.
Stroke (2004)

253 Citations

CREB-mediated Bcl-2 protein expression after ischemic preconditioning.

Robert Meller;Manabu Minami;Jennifer A. Cameron;Soren Impey.
Journal of Cerebral Blood Flow and Metabolism (2005)

231 Citations

Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures.

David C. Henshall;Jun Chen;Roger P. Simon.
Journal of Neurochemistry (2000)

218 Citations

Alterations in bcl-2 and caspase gene family protein expression in human temporal lobe epilepsy

D.C. Henshall;R.S. B. Clark;P.D. Adelson;M. Chen.
Neurology (2000)

207 Citations

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