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Norihiro Nishimoto

Norihiro Nishimoto

D-Index & Metrics

Immunology

D-Index
75
Citations
29511
World Ranking
1953
National Ranking
77

Overview

Norihiro Nishimoto is a researcher affiliated with Osaka University in Japan, focusing primarily on the field of medicine. Their research spans several subfields including rheumatology, molecular biology, pathology and forensic medicine, orthopedics and sports medicine, and surgery.

Their scientific contributions cover a variety of topics, notably:

  • Lymphoma Diagnosis and Treatment
  • Spondyloarthritis Studies and Treatments
  • Bone and Joint Diseases
  • Hip Disorders and Treatments
  • Protein Purification and Stability
  • Microencapsulation and Drying Processes
  • Analytical Chemistry and Chromatography

Among their recent publications are the following papers:

  • "A nationwide questionnaire survey on the prevalence of ankylosing spondylitis and non-radiographic axial spondyloarthritis in Japan", 2021, published in Modern Rheumatology
  • "Quantitative Analysis of Glassy State Relaxation and Ostwald Ripening during Annealing Using Freeze-Drying Microscopy", 2022, published in Pharmaceutics
  • "Selection of treatment regimens based on shared decision-making in patients with rheumatoid arthritis on remission in the FREE-J study", 2022, published in Lara D. Veeken
  • "WITHDRAWN: Ten-year follow-up of patients with refractory systemic juvenile idiopathic arthritis after the clinical trial of tocilizumab as a first biologic disease-modifying antirheumatic drug", 2025, published in EULAR Rheumatology Open
  • "Effectiveness and safety of tocilizumab, an anti-interleukin-6 receptor antibody, in 342 Japanese patients with multicentric Castleman disease: a 3-year, prospective, observational study", 2025, published in Modern Rheumatology

Frequent co-authors who have collaborated on multiple projects with Nishimoto include:

  • Tatsuya Atsumi
  • Keishi Fujio
  • Atsushi Kawakami
  • Masaaki Mori
  • Yoshiya Tanaka

Their work has been published across various venues, with repeated contributions to:

  • Modern Rheumatology
  • Pharmaceutics
  • Lara D. Veeken
  • EULAR Rheumatology Open

Best Publications

  • Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo.

    R Atreya;J Mudter;S Finotto;J Müllberg

  • Structure and function of a new STAT-induced STAT inhibitor

    Tetsuji Naka;Masashi Narazaki;Moritoshi Hirata;Tomoshige Matsumoto

  • Pathogenic Significance of Interleukin-6 (IL-6/BSF-2) in Castleman's Disease

    K Yoshizaki;T Matsuda;N Nishimoto;T Kuritani

  • Treatment of rheumatoid arthritis with humanized anti–interleukin-6 receptor antibody: A multicenter, double-blind, placebo-controlled trial

    Norihiro Nishimoto;Kazuyuki Yoshizaki;Nobuyuki Miyasaka;Kazuhiko Yamamoto

  • Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial

    Shumpei Yokota;Tomoyuki Imagawa;Masaaki Mori;Takako Miyamae

  • Humanized anti–interleukin-6 receptor antibody treatment of multicentric Castleman disease

    Norihiro Nishimoto;Yuzuru Kanakura;Katsuyuki Aozasa;Takeshi Johkoh

  • Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease.

    Norihiro Nishimoto;Kimio Terao;Toru Mima;Hideko Nakahara

  • Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

    Norihiro Nishimoto;Jun Hashimoto;Nobuyuki Miyasaka;Kazuhiko Yamamoto

  • A pilot randomized Trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease

    Hiroaki Ito;Masakazu Takazoe;Yoshihiro Fukuda;Toshifumi Hibi

  • TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling

    Christoph Becker;Massimo C. Fantini;Christoph Schramm;Hans A. Lehr

  • Interleukin 6: from bench to bedside.

    Norihiro Nishimoto;Tadamitsu Kishimoto

  • Therapeutic benefit of blocking interleukin‐6 activity with an anti–interleukin‐6 receptor monoclonal antibody in rheumatoid arthritis: A randomized, double‐blind, placebo‐controlled, dose‐escalation trial

    Ernest Choy;D A Isenberg;Toby Garrood;S Farrow

  • The paradigm of IL-6: from basic science to medicine

    Tetsuji Naka;Norihiro Nishimoto;Tadamitsu Kishimoto

  • Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy.

    Norihiro Nishimoto;Norihiro Nishimoto;Mitsuko Sasai;Mitsuko Sasai;Yoshihito Shima;Yoshihito Shima;Masashi Nakagawa;Masashi Nakagawa

  • The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis

    Qing Chang;Eirini Bournazou;Pasquale Sansone;Marjan Berishaj

  • Therapeutic efficacy of humanized recombinant anti-interleukin-6 receptor antibody in children with systemic-onset juvenile idiopathic arthritis.

    Shumpei Yokota;Takako Miyamae;Tomoyuki Imagawa;Naomi Iwata

  • Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis.

    Hideko Nakahara;Jian Song;Masamichi Sugimoto;Keisuke Hagihara

  • Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy

    Norihiro Nishimoto;Nobuyuki Miyasaka;Kazuhiko Yamamoto;Shinichi Kawai

  • Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5-year extension study

    Norihiro Nishimoto;Nobuyuki Miyasaka;Kazuhiko Yamamoto;Shinichi Kawai

  • Blockage of interleukin-6 receptor ameliorates joint disease in murine collagen-induced arthritis

    Nobuhiro Takagi;Masahiko Mihara;Yoichiro Moriya;Norihiro Nishimoto

Frequent Co-Authors

Kazuyuki Yoshizaki
Kazuyuki Yoshizaki Osaka University
Tadamitsu Kishimoto
Tadamitsu Kishimoto Osaka University
Tsuneyo Mimori
Tsuneyo Mimori Kyoto University
Yoshiya Tanaka
Yoshiya Tanaka University of Occupational and Environmental Health Japan
Masahiro Iwamoto
Masahiro Iwamoto University of Maryland, Baltimore
Tsutomu Takeuchi
Tsutomu Takeuchi Keio University
Hideki Yoshikawa
Hideki Yoshikawa Osaka University
Takayuki Sumida
Takayuki Sumida University of Tsukuba
David T. Curiel
David T. Curiel Washington University in St. Louis

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