World's Best Scientists 2026 revealed!
Award Badge
Biology and Biochemistry
Australia
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
101
Citations
41751
World Ranking
1428
National Ranking
35

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Australia Leader Award

Overview

Douglas J. Hilton is affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with a notable emphasis on medicine.

The main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

The subfields of study focus on:

  • Molecular Biology
  • Immunology
  • Genetics
  • Hematology
  • Neurology

The primary research topics covered are:

  • Platelet Disorders and Treatments
  • Immune Cell Function and Interaction
  • Genomics and Chromatin Dynamics
  • Nuclear Structure and Function
  • RNA Research and Splicing
  • Neuroblastoma Research and Treatments
  • Signaling Pathways in Disease

Recent papers authored or co-authored by Douglas J. Hilton include:

  • "Membrane budding is a major mechanism of in vivo platelet biogenesis," 2020, The Journal of Experimental Medicine
  • "In vivo clonal tracking reveals evidence of haemangioblast and haematomesoblast contribution to yolk sac haematopoiesis," 2023, Nature Communications
  • "Short-term particulate matter contamination severely compromises insect antennal olfactory perception," 2023, Nature Communications
  • "BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation," 2022, Nature Communications
  • "Chromosomes distribute randomly to, but not within, human neutrophil nuclear lobes," 2021, iScience

Frequent co-authors include:

  • Carolyn A. de Graaf
  • Christine Biben
  • Samir Taoudi
  • Alison Farley
  • Olivia Stonehouse

Common venues for publication are:

  • Nature Communications
  • Experimental Hematology
  • The Journal of Experimental Medicine
  • iScience
  • PROTEOMICS

Best Publications

  • A family of cytokine-inducible inhibitors of signalling

    Robyn Starr;Tracy A. Willson;Elizabeth M. Viney;Leecia J. L. Murray

  • Myeloid leukaemia inhibitory factor maintains the developmental potential of embryonic stem cells

    R L Williams;D J Hilton;S Pease;T A Willson

  • The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

    James M. Murphy;Peter E. Czabotar;Peter E. Czabotar;Joanne M. Hildebrand;Joanne M. Hildebrand;Isabelle S. Lucet

  • SOCS proteins: negative regulators of cytokine signaling.

    Danielle L. Krebs;Douglas J. Hilton

  • The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response.

    Warren S. Alexander;Douglas J. Hilton

  • SOCS3 negatively regulates IL-6 signaling in vivo.

    Ben A Croker;Danielle L Krebs;Jian-Guo Zhang;Sam Wormald

  • Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells.

    Timothy Gainsford;Tracy A. Willson;Donald Metcalf;Emanuela Handman

  • SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine

    Warren S Alexander;Robyn Starr;Robyn Starr;Jennifer E Fenner;Clare L Scott;Clare L Scott

  • Twenty proteins containing a C-terminal SOCS box form five structural classes

    Douglas J. Hilton;Rachael T. Richardson;Warren S. Alexander;Elizabeth M. Viney

  • The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

    Jian Guo Zhang;Alison Farley;Sandra E. Nicholson;Tracy A. Willson

  • Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation

    Ashley Scott Mansell;Rosealee Anne Smith;Sarah L Doyle;Pearl Gray

  • SOCS-3 is an insulin-induced negative regulator of insulin signaling.

    Brice Emanuelli;Pascal Peraldi;Chantal Filloux;Dominique Sawka-Verhelle

  • SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice.

    B Emanuelli;P Peraldi;C Filloux;C Chavey

  • SOCS: physiological suppressors of cytokine signaling.

    D.L. Krebs;D.J. Hilton

  • Inhibitors of cytokine signal transduction.

    Samuel Wormald;Douglas J. Hilton

  • Gigantism in mice lacking suppressor of cytokine signalling-2

    Donald Metcalf;Christopher J. Greenhalgh;Elizabeth Viney;Tracy A. Willson

  • Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

    Sandra E. Nicholson;David De Souza;Louis J. Fabri;Jason Corbin

  • The SOCS box: a tale of destruction and degradation

    Benjamin T Kile;Brenda A Schulman;Warren S Alexander;Nicos A Nicola

  • Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

    Sandra E. Nicholson;Tracy A. Willson;Alison Farley;Robyn Starr

  • Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

    Douglas J. Hilton;Jian-Guo Zhang;Donald Metcalf;Warren S. Alexander

Frequent Co-Authors

Warren S. Alexander
Warren S. Alexander Walter and Eliza Hall Institute of Medical Research
Nicos A. Nicola
Nicos A. Nicola Walter and Eliza Hall Institute of Medical Research
Donald Metcalf
Donald Metcalf Walter and Eliza Hall Institute of Medical Research
Tracy A. Willson
Tracy A. Willson Walter and Eliza Hall Institute of Medical Research
Benjamin T. Kile
Benjamin T. Kile University of Adelaide
Jian-Guo Zhang
Jian-Guo Zhang Beijing Institute for Brain Disorders
Sandra E. Nicholson
Sandra E. Nicholson Walter and Eliza Hall Institute of Medical Research
Richard J. Simpson
Richard J. Simpson La Trobe University
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research
Andrew W. Roberts
Andrew W. Roberts Walter and Eliza Hall Institute of Medical Research

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Douglas J. Hilton

Trending Scientists