D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 45 Citations 11,825 108 World Ranking 12808 National Ranking 303

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Amino acid
  • Cytokine

The scientist’s investigation covers issues in Cell biology, Signal transduction, Molecular biology, Suppressor of cytokine signalling and Immunology. The concepts of his Cell biology study are interwoven with issues in Acquired immune system, Spectrin, Ligand, Dendritic cell and Actin cytoskeleton. His study in Signal transduction is interdisciplinary in nature, drawing from both RIPK1, Phosphorylation and Leukemia inhibitory factor.

His research integrates issues of Multiprotein complex, Kinase and Programmed cell death, Necroptosis in his study of Phosphorylation. His Molecular biology study combines topics in areas such as 5-HT5A receptor, Common gamma chain, Interleukin-21 receptor, Interleukin 1 receptor, type I and Glycoprotein 130. His Suppressor of cytokine signalling study combines topics from a wide range of disciplines, such as Suppressor of cytokine signaling 1, Cytokine, Genetically modified mouse and STAT protein.

His most cited work include:

  • SOCS3 negatively regulates IL-6 signaling in vivo. (695 citations)
  • The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism (643 citations)
  • The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism (643 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Cell biology, Signal transduction, Molecular biology, Immunology and Leukemia inhibitory factor. A large part of his Cell biology studies is devoted to Suppressor of cytokine signalling. His Signal transduction research integrates issues from Programmed cell death and Phosphorylation.

His study explores the link between Molecular biology and topics such as Receptor that cross with problems in Stereochemistry. In the subject of general Immunology, his work in Autoimmunity, CD8 and Interferon is often linked to Systemic lupus erythematosus and Lupus erythematosus, thereby combining diverse domains of study. His Leukemia inhibitory factor research is multidisciplinary, incorporating elements of Endocrinology, Glycoprotein 130, Internal medicine and Trophoblast.

He most often published in these fields:

  • Cell biology (53.69%)
  • Signal transduction (21.48%)
  • Molecular biology (20.13%)

What were the highlights of his more recent work (between 2013-2020)?

  • Cell biology (53.69%)
  • Cancer research (16.78%)
  • Immunology (20.81%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Cancer research, Immunology, Leukemia inhibitory factor and CD8. His Cell biology research incorporates elements of Cellular differentiation, Immune system, Antigen, Receptor and Ubiquitin ligase. The Cancer research study combines topics in areas such as Missense mutation, Heterozygote advantage, Compound heterozygosity and Programmed cell death, Necroptosis.

His Leukemia inhibitory factor research is multidisciplinary, relying on both Treatment strategy, Trophoblast, Glycoprotein 130 and Ectopic pregnancy. His research in Signal transduction intersects with topics in Cell migration, Reelin, DAB1, Cerebral cortex and Phosphorylation. Jian-Guo Zhang combines subjects such as Suppressor of cytokine signaling 1, SOCS3, Suppressor of cytokine signalling and Cytokine with his study of Cytotoxic T cell.

Between 2013 and 2020, his most popular works were:

  • CIS is a potent checkpoint in NK cell–mediated tumor immunity (138 citations)
  • CIS is a potent checkpoint in NK cell–mediated tumor immunity (138 citations)
  • Mpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferation. (85 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Amino acid
  • Immune system

Cell biology, Immunology, Cancer research, Cell and Immunotherapy are his primary areas of study. He is interested in Signal transduction, which is a field of Cell biology. His Signal transduction study integrates concerns from other disciplines, such as Transgene, Autoimmunity, Bcl-2 family and Gene knockdown.

His work on T cell as part of general Immunology research is frequently linked to Pregnancy-associated plasma protein A, thereby connecting diverse disciplines of science. His studies deal with areas such as Mutation, Missense mutation, Heterozygote advantage and Programmed cell death, Necroptosis as well as Cancer research. His biological study spans a wide range of topics, including Janus kinase 1, CISH and Interferon gamma.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

SOCS3 negatively regulates IL-6 signaling in vivo.

Ben A Croker;Danielle L Krebs;Jian-Guo Zhang;Sam Wormald.
Nature Immunology (2003)

883 Citations

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

James M. Murphy;Peter E. Czabotar;Peter E. Czabotar;Joanne M. Hildebrand;Joanne M. Hildebrand;Isabelle S. Lucet.
Immunity (2013)

780 Citations

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

Jian Guo Zhang;Alison Farley;Sandra E. Nicholson;Tracy A. Willson.
Proceedings of the National Academy of Sciences of the United States of America (1999)

755 Citations

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

Sandra E. Nicholson;David De Souza;Louis J. Fabri;Jason Corbin.
Proceedings of the National Academy of Sciences of the United States of America (2000)

553 Citations

Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

Douglas J. Hilton;Jian-Guo Zhang;Donald Metcalf;Warren S. Alexander.
Proceedings of the National Academy of Sciences of the United States of America (1996)

521 Citations

Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

Sandra E. Nicholson;Tracy A. Willson;Alison Farley;Robyn Starr.
The EMBO Journal (1999)

517 Citations

Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

Lorraine A. O Reilly;Lin Tai;Lily Lee;Elizabeth A. Kruse;Elizabeth A. Kruse.
Nature (2009)

363 Citations

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity

Jennifer Eve Fenner;Robyn J Starr;Ann L Cornish;Ann L Cornish;Jian-Guo Zhang.
Nature Immunology (2006)

315 Citations

LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

Helmut Butzkueven;Jian Guo Zhang;Merja Soilu-Hanninen;Hubertus Hochrein.
Nature Medicine (2002)

299 Citations

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

Jian Guo Zhang;Jian Guo Zhang;Peter E. Czabotar;Peter E. Czabotar;Antonia N. Policheni;Antonia N. Policheni;Irina Caminschi;Irina Caminschi;Irina Caminschi.
Immunity (2012)

295 Citations

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