Jian-Guo Zhang

Overview

Best Publications

• The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

  James M. Murphy;Peter E. Czabotar;Peter E. Czabotar;Joanne M. Hildebrand;Joanne M. Hildebrand;Isabelle S. Lucet

  1187
  Citations

• SOCS3 negatively regulates IL-6 signaling in vivo.

  Ben A Croker;Danielle L Krebs;Jian-Guo Zhang;Sam Wormald

  1005
  Citations

• The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

  Jian Guo Zhang;Alison Farley;Sandra E. Nicholson;Tracy A. Willson

  831
  Citations

• Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

  Sandra E. Nicholson;David De Souza;Louis J. Fabri;Jason Corbin

  584
  Citations

• Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction

  Sandra E. Nicholson;Tracy A. Willson;Alison Farley;Robyn Starr

  543
  Citations

• Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

  Douglas J. Hilton;Jian-Guo Zhang;Donald Metcalf;Warren S. Alexander

  539
  Citations

• Membrane-bound Fas ligand only is essential for Fas-induced apoptosis

  Lorraine A. O Reilly;Lin Tai;Lily Lee;Elizabeth A. Kruse;Elizabeth A. Kruse

  466
  Citations

• The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

  Jian Guo Zhang;Jian Guo Zhang;Peter E. Czabotar;Peter E. Czabotar;Antonia N. Policheni;Antonia N. Policheni;Irina Caminschi;Irina Caminschi;Irina Caminschi

  404
  Citations

• CIS is a potent checkpoint in NK cell–mediated tumor immunity

  Rebecca B. Delconte;Tatiana B Kolesnik;Laura F. Dagley;Laura F. Dagley;Jai Rautela;Jai Rautela

  394
  Citations

• Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity

  Jennifer Eve Fenner;Robyn J Starr;Ann L Cornish;Ann L Cornish;Jian-Guo Zhang

  348
  Citations

• LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

  Helmut Butzkueven;Jian Guo Zhang;Merja Soilu-Hanninen;Hubertus Hochrein

  323
  Citations

• SOCS3 Is a Critical Physiological Negative Regulator of G-CSF Signaling and Emergency Granulopoiesis

  Ben A Croker;Donald Metcalf;Lorraine Robb;Wei Wei

  321
  Citations

• C-terminal Extension of Truncated Recombinant Proteins in Escherichia coli with a 10Sa RNA Decapeptide

  Guo-Fen Tu;Gavin E. Reid;Jian-Guo Zhang;Robert L. Moritz

  318
  Citations

• Oncostatin M promotes bone formation independently of resorption when signaling through leukemia inhibitory factor receptor in mice

  Emma C. Walker;Narelle E. McGregor;Ingrid J. Poulton;Melissa Solano;Melissa Solano

  298
  Citations

• Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned Il-13 receptor and Il-4 receptor alpha-chains.

  Jian-Guo Zhang;Douglas J. Hilton;Tracy A. Willson;Clare McFarlane

  274
  Citations

• Biological Evidence That SOCS-2 Can Act Either as an Enhancer or Suppressor of Growth Hormone Signaling

  Christopher J. Greenhalgh;Donald Metcalf;Anne L. Thaus;Jason E. Corbin

  219
  Citations

• DEC-205 is a cell surface receptor for CpG oligonucleotides

  Mireille H Lahoud;Fatma Ahmet;Fatma Ahmet;Jian-Guo Zhang;Simone Meuter;Simone Meuter

  202
  Citations

• The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo.

  Jian-Guo Zhang;Donald Metcalf;Steven Rakar;Maria Asimakis

  201
  Citations

• SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.

  Danielle L. Krebs;Rachel T. Uren;Donald Metcalf;Steven Rakar

  183
  Citations

• Suppressors of cytokine signaling (SOCS): Negative regulators of signal transduction

  Warren S. Alexander;Robyn Starr;Donald Metcalf;Sandra E. Nicholson

  169
  Citations