James E. Vince

Overview

Best Publications

• IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

  James E. Vince;W. Wei-Lynn Wong;Nufail Khan;Rebecca Feltham

  1271
  Citations

• Recruitment of the Linear Ubiquitin Chain Assembly Complex Stabilizes the TNF-R1 Signaling Complex and Is Required for TNF-Mediated Gene Induction

  Tobias L. Haas;Christoph H. Emmerich;Christoph H. Emmerich;Bjã¶rn Gerlach;Bjã¶rn Gerlach;Anna C. Schmukle

  836
  Citations

• Pyroptosis versus necroptosis: similarities, differences, and crosstalk

  Daniel Frank;Daniel Frank;James E. Vince;James E. Vince

  819
  Citations

• RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

  Kate E. Lawlor;Nufail Khan;Alison Mildenhall;Motti Gerlic

  660
  Citations

• RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

  James A Rickard;James A Rickard;Joanne A O'Donnell;Joanne A O'Donnell;Joseph M Evans;Joseph M Evans;Najoua Lalaoui;Najoua Lalaoui

  634
  Citations

• Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

  James E. Vince;W. Wei Lynn Wong;W. Wei Lynn Wong;Ian Gentle;Kate E. Lawlor;Kate E. Lawlor

  561
  Citations

• AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC

  V Sagulenko;S J Thygesen;D P Sester;A Idris

  515
  Citations

• Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.

  Stephanie A. Conos;Stephanie A. Conos;Kaiwen W Chen;Dominic De Nardo;Dominic De Nardo;Hideki Hara

  474
  Citations

• The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

  P Menu;J E Vince

  416
  Citations

• TRAF2 Must Bind to Cellular Inhibitors of Apoptosis for Tumor Necrosis Factor (TNF) to Efficiently Activate NF-κB and to Prevent TNF-induced Apoptosis

  James E. Vince;Delara Pantaki;Rebecca Feltham;Peter D. Mace

  268
  Citations

• TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

  James E. Vince;Diep Chau;Bernard Callus;W. Wei-Lynn Wong

  265
  Citations

• Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming

  Ramanjaneyulu Allam;Kate E Lawlor;Kate E Lawlor;Eric Chi-Wang Yu;Alison L Mildenhall;Alison L Mildenhall

  244
  Citations

• The Pathogen Candida albicans Hijacks Pyroptosis for Escape from Macrophages

  Nathalie Uwamahoro;Jiyoti Verma-Gaur;Hsin-Hui Shen;Yue Qu

  228
  Citations

• Surface determinants of Leishmania parasites and their role in infectivity in the mammalian host.

  Thomas Naderer;James E. Vince;Malcolm J. McConville

  208
  Citations

• EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation

  Jaclyn S. Pearson;Cristina Giogha;Sabrina Mühlen;Ueli Nachbur

  191
  Citations

• The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

  James E. Vince;James E. Vince;Dominic De Nardo;Dominic De Nardo;Wenqing Gao;Angelina J. Vince

  186
  Citations

• cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- And RIPK3-dependent manner

  W. Wei-Lynn Wong;W. Wei-Lynn Wong;W. Wei-Lynn Wong;James E. Vince;James E. Vince;Najoua Lalaoui;Najoua Lalaoui;Kate E. Lawlor;Kate E. Lawlor

  182
  Citations

• The intersection of cell death and inflammasome activation.

  James E. Vince;James E. Vince;John Silke;John Silke

  177
  Citations

• Oxidative Stress and NLRP3-Inflammasome Activity as Significant Drivers of Diabetic Cardiovascular Complications: Therapeutic Implications.

  Arpeeta Sharma;Mitchel Tate;Geetha Mathew;James E Vince;James E Vince

  177
  Citations

• TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1.

  D M Moujalled;W D Cook;T Okamoto;J J Murphy;J J Murphy

  168
  Citations