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Mathieu J.M. Bertrand

Mathieu J.M. Bertrand

D-Index & Metrics

Molecular Biology

D-Index
49
Citations
18673
World Ranking
2592
National Ranking
32

Overview

Mathieu J.M. Bertrand is affiliated with Ghent University in Belgium and conducts research primarily in biochemistry, genetics, and molecular biology, with additional focus on immunology, microbiology, and medicine. Their work spans several subfields, including immunology, molecular biology, cancer research, epidemiology, and pulmonary and respiratory medicine.

The research topics covered by Bertrand emphasize various aspects of cell death and immune system regulation, including:

  • Cell death mechanisms and regulation
  • Interferon and immune responses
  • NF-κB signaling pathways
  • Immune response and inflammation
  • Autophagy in disease and therapy
  • Phagocytosis and immune regulation
  • Inflammasome and immune disorders

Bertrand's recent publications highlight notable contributions to the understanding of inflammation, cell death, and signaling pathways. These papers include:

  • Death by TNF: a road to inflammation, 2022, Nature Reviews. Immunology
  • Apoptotic cell death in disease-Current understanding of the NCCD 2023, 2023, Cell Death and Differentiation
  • Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation, 2020, Nature Communications
  • RIPK1 Kinase-Dependent Death: A Symphony of Phosphorylation Events, 2020, Trends in Cell Biology
  • A20 and Cell Death-driven Inflammation, 2020, Trends in Immunology

Bertrand frequently collaborates with several co-authors, which include:

  • Dario Priem
  • Tom Delanghe
  • Geert Loo
  • Jon Huyghe
  • Yves Dondelinger

The scientist's work appears consistently in several key publication venues such as:

  • Cell Death and Disease
  • Cell Death and Differentiation
  • Trends in Immunology
  • Cell Reports
  • Autophagy

Best Publications

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

    Lorenzo Galluzzi;Ilio Vitale;Stuart A. Aaronson;John M. Abrams

  • cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

    Mathieu J.M. Bertrand;Snezana Milutinovic;Kathleen M. Dickson;Wai Chi Ho

  • Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

    L. Galluzzi;J. M. Bravo-San Pedro;I. Vitale;S. A. Aaronson

  • MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates

    Yves Dondelinger;Wim Declercq;Sylvie Montessuit;Ria Roelandt

  • An Overview of the MAGE Gene Family with the Identification of All Human Members of the Family

    Patrick Chomez;Olivier De Backer;Mathieu Bertrand;Etienne De Plaen

  • NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling

    Yves Dondelinger;Sandrine Jouan-Lanhouet;Tatyana Divert;Emilie Theatre

  • Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity.

    Tania Løve Aaes;Agnieszka Kaczmarek;Tinneke Delvaeye;Bram De Craene

  • Cellular Inhibitors of Apoptosis cIAP1 and cIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2

    Mathieu J.M. Bertrand;Karine Doiron;Katherine Labbé;Robert G. Korneluk

  • cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

    N Vanlangenakker;T Vanden Berghe;P Bogaert;B Laukens

  • RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis

    Nozomi Takahashi;Lars Vereecke;Mathieu J. M. Bertrand;Linde Duprez

  • RIPK3 contributes to TNFR1-mediated RIPK1 kinase-dependent apoptosis in conditions of cIAP1/2 depletion or TAK1 kinase inhibition.

    Yves Dondelinger;Miguel Aguileta;Vera Goossens;Christel Dubuisson

  • TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members.

    N Vanlangenakker;M J M Bertrand;P Bogaert;P Vandenabeele

  • The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress

    Richard Jäger;Mathieu J.M. Bertrand;Adrienne M. Gorman;Peter Vandenabeele

  • More to Life than NF-κB in TNFR1 Signaling

    Adrian T. Ting;Mathieu J.M. Bertrand

  • NOD-like receptors and the innate immune system: coping with danger, damage and death.

    Kristof Kersse;Mathieu J.M. Bertrand;Mohamed Lamkanfi;Peter Vandenabeele

  • Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

    Q Remijsen;V Goossens;S Grootjans;C Van den Haute

  • Molecular crosstalk between apoptosis, necroptosis, and survival signaling

    Tom Vanden Berghe;William J Kaiser;Mathieu Jm Bertrand;Peter Vandenabeele

  • When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157.

    Diego Rojas-Rivera;Tinneke Delvaeye;Ria Roelandt;Wim Nerinckx

  • MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death.

    Yves Dondelinger;Tom Delanghe;Diego Rojas-Rivera;Dario Priem

  • Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation

    Lucie Laurien;Masahiro Nagata;Hannah Schünke;Tom Delanghe

Frequent Co-Authors

Peter Vandenabeele
Peter Vandenabeele Ghent University
Simone Fulda
Simone Fulda Goethe University Frankfurt
Tom Vanden Berghe
Tom Vanden Berghe University of Antwerp
Wim Declercq
Wim Declercq Ghent University
Geert van Loo
Geert van Loo Ghent University
Sophie Janssens
Sophie Janssens Ghent University
Michel Samson
Michel Samson University of Rennes
Manolis Pasparakis
Manolis Pasparakis University of Cologne
Philip A. Barker
Philip A. Barker University of British Columbia
Muhammad Farooq
Muhammad Farooq Sultan Qaboos University

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