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D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
20963
World Ranking
4345
National Ranking
148

Overview

Philip A. Barker is affiliated with the University of British Columbia in Canada. Their research primarily spans the fields of Neuroscience and Biochemistry, Genetics and Molecular Biology, with a specialized focus on Cellular and Molecular Neuroscience, Molecular Biology, Neurology, Developmental Neuroscience, and Physiology.

The main topics covered in their body of work include:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurogenesis and Neuroplasticity Mechanisms
  • Neuroscience and Neuropharmacology Research
  • Nerve Injury and Regeneration
  • Signaling Pathways in Disease
  • Cell Death Mechanisms and Regulation
  • Ion Channels and Receptors

Philip A. Barker has contributed to various peer-reviewed publications, collaborating frequently with researchers such as Julien Gibon, Andrés de León, Teresa Cramer, Raminder Gill, and Zahra S. Thirouin.

Their work has appeared in multiple scientific journals including:

  • eNeuro
  • Science Advances
  • Frontiers in Molecular Neuroscience
  • Journal of Neuroscience
  • Zurich Open Repository and Archive (University of Zurich)

Selected recent papers authored or co-authored by Philip A. Barker include:

  • Cross-talk between GABAergic postsynapse and microglia regulate synapse loss after brain ischemia, 2022, Science Advances
  • NGF-Dependent and BDNF-Dependent DRG Sensory Neurons Deploy Distinct Degenerative Signaling Mechanisms, 2020, eNeuro
  • Collapsin Response Mediator Protein 4 (CRMP4) Facilitates Wallerian Degeneration and Axon Regeneration following Sciatic Nerve Injury, 2020, eNeuro
  • Mitochondrial Reactive Oxygen Species Mediate Activation of TRPV1 and Calcium Entry Following Peripheral Sensory Axotomy, 2022, Frontiers in Molecular Neuroscience
  • APP Genetic Deficiency Alters Intracellular Ca2+ Homeostasis and Delays Axonal Degeneration in Dorsal Root Ganglion Sensory Neurons, 2022, Journal of Neuroscience

Best Publications

  • cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

    Mathieu J.M. Bertrand;Snezana Milutinovic;Kathleen M. Dickson;Wai Chi Ho

  • Neurotrophin signaling through the p75 neurotrophin receptor.

    Philippe P Roux;Philip A Barker

  • Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells.

    Philip A. Barker;Eric M. Shooter

  • Impact of lower atmospheric carbon dioxide on tropical mountain ecosystems

    F. Alayne Street-Perrott;Yongsong Huang;R. Alan Perrott;Geoffrey Eglinton

  • De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia

    Julie Gauthier;Nathalie Champagne;Ronald G. Lafrenière;Lan Xiong

  • Multiple Sclerosis: Fas Signaling in Oligodendrocyte Cell Death

    Sameer D. D'Souza;Bruno Bonetti;Vijayabalan Balasingam;Neil R. Cashman

  • Constitutive Nuclear Factor-κB Activity Is Required for Central Neuron Survival

    Asha L. Bhakar;Laura-Lee Tannis;Christine Zeindler;Maria Pia Russo

  • Vasculature Guides Migrating Neuronal Precursors in the Adult Mammalian Forebrain via Brain-Derived Neurotrophic Factor Signaling

    Marina Snapyan;Morgane Lemasson;Monika S. Brill;Mathieu Blais

  • The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic disease.

    Philip A. Barker;Amir Salehi

  • Detection of brain-derived neurotrophic factor-like activity in fibroblasts and Schwann cells: inhibition by antibodies to NGF.

    Ann Acheson;Philip A. Barker;Ralph F. Alderson;Freda D. Miller

  • Cellular Inhibitors of Apoptosis cIAP1 and cIAP2 Are Required for Innate Immunity Signaling by the Pattern Recognition Receptors NOD1 and NOD2

    Mathieu J.M. Bertrand;Karine Doiron;Katherine Labbé;Robert G. Korneluk

  • NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis.

    Amir H Salehi;Philippe P Roux;Chris J Kubu;Christine Zeindler

  • p75NTR is positively promiscuous: Novel partners and new insights

    Philip A Barker

  • Nuclear factor kB signaling regulates neuronal morphology and cocaine reward

    Scott J. Russo;Matthew B. Wilkinson;Michelle S. Mazei-Robison;David M. Dietz

  • p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure.

    Philippe P. Roux;Michael A. Colicos;Philip A. Barker;Timothy E. Kennedy

  • A high-resolution paleoclimate record spanning the past 25,000 years in southern East Africa.

    Thomas C. Johnson;Erik T. Brown;James McManus;Sylvia Barry

  • Transgenic Mice Expressing the Intracellular Domain of the p75 Neurotrophin Receptor Undergo Neuronal Apoptosis

    Marta Majdan;Christian Lachance;Andrew Gloster;Raquel Aloyz

  • Tissue-specific alternative splicing generates two isoforms of the trkA receptor.

    P.A. Barker;C. Lomen-Hoerth;E.M. Gensch;S.O. Meakin

  • Biogenic silica: a neglected component of the coupled global continental biogeochemical cycles of carbon and silicon

    F. Alayne Street-Perrott;Philip A. Barker

  • Experimental dissolution of diatom silica in concentrated salt solutions and implications for paleoenvironmental reconstruction

    Philip Barker;Jean-Charles Fontes;FranÇoise Gasse

Frequent Co-Authors

Melanie J. Leng
Melanie J. Leng University of Nottingham
F. Alayne Street-Perrott
F. Alayne Street-Perrott Swansea University
Richard J. Telford
Richard J. Telford University of Bergen
Hilary J. Sloane
Hilary J. Sloane British Geological Survey
Neil Roberts
Neil Roberts Plymouth University
Philippe Séguéla
Philippe Séguéla Montreal Neurological Institute and Hospital
Philippe P. Roux
Philippe P. Roux University of Montreal
David Williamson
David Williamson Institut de Recherche pour le Développement
Eric M. Shooter
Eric M. Shooter Stanford University
Françoise Gasse
Françoise Gasse Aix-Marseille University

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