World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
69
Citations
17606
World Ranking
7359
National Ranking
3368

Overview

Jay L. Hess is affiliated with Indiana University in the United States and has contributed to the field of medicine through research focused mainly on medical education, public health, immunology, oncology, and genetics. Their work addresses diverse topics including innovations in medical education, medical education and admissions processes, diversity and career in medicine, immunotherapy and immune responses, cancer immunotherapy and biomarkers, glioma diagnosis and treatment, and the broader impacts of health and medical research.

Several recent publications highlight Jay L. Hess's engagement in these areas. Notable papers include:

  • Medical School Without Walls: 50 Years of Regional Campuses at Indiana University School of Medicine, 2022, published in Academic Medicine
  • O-09.03 Preliminary immunogenicity results from the dose escalation phase of a first-in-human study of the mRNA-based cancer vaccine CVGBM in patients with newly diagnosed MGMT-unmethylated glioblastoma, 2025, presented at Oral Presentations
  • Promoting Regional Campus Excellence: The Scholarly Concentrations Program at Indiana University School of Medicine, 2021, published in Journal of Regional Medical Campuses

Jay L. Hess frequently collaborates with other researchers such as Paul M. Wallach, Deborah R. Birnbaum, Elizabeth Ryan, Brandon T. Pieczko, and Laura de Freitas Chama. These collaborations have resulted in multiple co-authored works, reflecting a multi-disciplinary approach particularly within medical education and oncology fields.

The primary venues for Jay L. Hess's publications include:

  • Academic Medicine
  • Oral Presentations
  • Journal of Regional Medical Campuses

Jay L. Hess's research contributions predominantly fall under the broad field of medicine with specific subfields concentrating on public health, environmental and occupational health, gender studies, immunology, oncology, and genetics.

The main topics covered in their research further underline their focus on medical education innovation, diversity in medicine, cancer-related immunotherapy, and neurological cancer treatment strategies. This multidisciplinary interest supports a comprehensive approach to addressing medical education alongside emerging therapeutic modalities such as mRNA cancer vaccines.

Best Publications

  • MLL targets SET domain methyltransferase activity to Hox gene promoters.

    Thomas A Milne;Scott D Briggs;Hugh W Brock;Mary Ellen Martin

  • Altered Hox expression and segmental identity in Mll -mutant mice

    Benjamin D. Yu;Jay L. Hess;Susan E. Horning;Gary A. J. Brown

  • Physical Association and Coordinate Function of the H3 K4 Methyltransferase MLL1 and the H4 K16 Acetyltransferase MOF

    Yali Dou;Thomas A. Milne;Thomas A. Milne;Alan J. Tackett;Edwin R. Smith

  • Menin Associates with a Trithorax Family Histone Methyltransferase Complex and with the Hoxc8 Locus

    Christina M. Hughes;Orit Rozenblatt-Rosen;Thomas A. Milne;Terry D. Copeland

  • Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

    Thomas A. Milne;Christina M. Hughes;Ricardo Lloyd;Zhaohai Yang

  • MLL: a histone methyltransferase disrupted in leukemia.

    Jay L. Hess

  • A role for the MLL fusion partner ENL in transcriptional elongation and chromatin modification

    Dorothee Mueller;Christian Bach;Deniz Zeisig;Maria Paz Garcia-Cuellar

  • Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia

    Jolanta Grembecka;Shihan He;Aibin Shi;Trupta Purohit

  • Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization.

    Bernd B. Zeisig;Tom Milne;María Paz García-Cuéllar;Silke Schreiner

  • MLL, A MAMMALIAN TRITHORAX-GROUP GENE, FUNCTIONS AS A TRANSCRIPTIONAL MAINTENANCE FACTOR IN MORPHOGENESIS

    Benjamin D. Yu;Robin D. Hanson;Jay L. Hess;Susan E. Horning

  • The pathogenesis of mixed-lineage leukemia.

    Andrew G. Muntean;Jay L. Hess

  • Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo.

    Dmitry Borkin;Shihan He;Hongzhi Miao;Katarzyna Kempinska

  • Targeting MLL1 H3K4 methyltransferase activity in mixed-lineage leukemia.

    Fang Cao;Elizabeth C. Townsend;Hacer Karatas;Jing Xu

  • Mammalian Trithorax and Polycomb-group homologues are antagonistic regulators of homeotic development

    Robin D. Hanson;Jay L. Hess;Benjamin D. Yu;Patricia Ernst;Patricia Ernst

  • Base-Pair Resolution DNA Methylation Sequencing Reveals Profoundly Divergent Epigenetic Landscapes in Acute Myeloid Leukemia

    Altuna Akalin;Francine E. Garrett-Bakelman;Matthias Kormaksson;Jennifer Busuttil

  • Defects in yolk sac hematopoiesis in Mll-null embryos

    Jay L. Hess;Benjamin D. Yu;Bin Li;Rob Hanson

  • MLL associates specifically with a subset of transcriptionally active target genes

    Thomas A. Milne;Yali Dou;Mary Ellen Martin;Hugh W. Brock

  • The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.

    Andrew G. Muntean;Jiaying Tan;Kajal Sitwala;Yongsheng Huang

  • Leukemogenic MLL Fusion Proteins Bind across a Broad Region of the Hox a9 Locus, Promoting Transcription and Multiple Histone Modifications

    Thomas A. Milne;Mary Ellen Martin;Hugh W. Brock;Robert K. Slany

  • Interaction of MLL Amino Terminal Sequences with Menin Is Required for Transformation

    Corrado Caslini;Zhaohai Yang;Mohamad El-Osta;Thomas A. Milne

Frequent Co-Authors

Thomas A. Milne
Thomas A. Milne University of Oxford
Yali Dou
Yali Dou University of Southern California
Ivan Maillard
Ivan Maillard University of Pennsylvania
Ali Shilatifard
Ali Shilatifard Northwestern University
Janice E. Clements
Janice E. Clements Johns Hopkins University School of Medicine
Duxin Sun
Duxin Sun University of Michigan–Ann Arbor
Thomas W. Weickert
Thomas W. Weickert SUNY Upstate Medical University
Robert G. Roeder
Robert G. Roeder Rockefeller University
Stanley J. Korsmeyer
Stanley J. Korsmeyer Harvard University
Ming T. Tsuang
Ming T. Tsuang University of California, San Diego

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Jay L. Hess

Trending Scientists

Recently Published Articles